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Q21H90 (PSD_SACD2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:Sde_2679
OrganismSaccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) [Complete proteome] [HAMAP]
Taxonomic identifier203122 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Saccharophagus

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 249249Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000262147
Chain250 – 28637Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000262148

Sites

Site249 – 2502Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2501Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q21H90 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: A0E3C533E8C4FD55

FASTA28631,844
        10         20         30         40         50         60 
MKDDLFIALQ RIIPHHAFSR LVGWFAATKI RWIKHLFITK FINAYNVNMA EALEPNPENY 

        70         80         90        100        110        120 
ANFNDFFVRA LKPDARPIAS EANAIVSPAD GAVSQLGEIS GDKIFQAKNH WFSIKELLAC 

       130        140        150        160        170        180 
DDELAEQFMG GSFATIYLSP SDYHRVHMPA AGLLTQMNYI PGDLFSVNPV TTENVAGLFA 

       190        200        210        220        230        240 
RNERIAAIFD TEFGPMAVVM VGAMIVASIE TVWDGQITPA SREVKRNVYS KPREIKLGKG 

       250        260        270        280 
DEMGRFKLGS TAVLLFPKGA IKWKEDIKAE TTLRMGEMIA ELQTQA

« Hide

References

[1]"Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T."
Weiner R.M., Taylor L.E. II, Henrissat B., Hauser L., Land M., Coutinho P.M., Rancurel C., Saunders E.H., Longmire A.G., Zhang H., Bayer E.A., Gilbert H.J., Larimer F., Zhulin I.B., Ekborg N.A., Lamed R., Richardson P.M., Borovok I., Hutcheson S.
PLoS Genet. 4:E1000087-E1000087(2008) [PubMed: 18516288] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2-40 / ATCC 43961 / DSM 17024.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000282 Genomic DNA. Translation: ABD81939.1.
RefSeqYP_528151.1. NC_007912.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ21H90.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3968459.
GenomeReviewsGene locus Sde_2679 in contig CP000282_GR.
KEGGsde:Sde_2679.
NMPDRfig|203122.1.peg.3316.
PATRIC23404442. VBISacDeg56404_2886.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG302256.
OMASMATVWH.
PhylomeDBQ21H90.
ProtClustDBCLSK2528773.

Enzyme and pathway databases

BioCycSDEG203122:SDE_2679-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_SACD2
AccessionPrimary (citable) accession number: Q21H90
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: April 18, 2006
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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