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Q21GQ5

- GLSA_SACD2

UniProt

Q21GQ5 - GLSA_SACD2

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Protein
Glutaminase
Gene
glsA, Sde_2867
Organism
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei66 – 661Substrate By similarity
Binding sitei116 – 1161Substrate By similarity
Binding sitei160 – 1601Substrate By similarity
Binding sitei167 – 1671Substrate By similarity
Binding sitei191 – 1911Substrate By similarity
Binding sitei243 – 2431Substrate By similarity
Binding sitei261 – 2611Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSDEG203122:GI2M-2915-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Sde_2867
OrganismiSaccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Taxonomic identifieri203122 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeSaccharophagus
ProteomesiUP000001947: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307GlutaminaseUniRule annotation
PRO_1000048352Add
BLAST

Proteomic databases

PRIDEiQ21GQ5.

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi203122.Sde_2867.

Structurei

3D structure databases

ProteinModelPortaliQ21GQ5.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q21GQ5-1 [UniParc]FASTAAdd to Basket

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MDAIDYKKIF SEIVNELSSE DEKGSVATYI PELANVDPNK LGMHLTTVTN    50
QHFAYGDAEE AFSIQSIAKV WSLTLALKHL GADTWQRVGV EPSGTAFNSL 100
VQLEYEMGIP RNPFINAGAI VVCDILVSCL KNPKEDLLDF IRTSSGIPSI 150
EYCPVIAESE VKTGHRNYAL AHMMKGFGNI HNDVDCVLDL YFSLCSIKLT 200
CKQLAQAFLF LAAGGVNPAT QQQVITPKRT KRINSIMQMC GFYDEAGEFA 250
FKVGLPGKSG VGGGIVAVHP GKYCIAVFSP RLNASGNSVK AMKVLEALTT 300
KTELSIF 307
Length:307
Mass (Da):33,379
Last modified:April 18, 2006 - v1
Checksum:i93B71207B3CEC813
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000282 Genomic DNA. Translation: ABD82124.1.
RefSeqiYP_528336.1. NC_007912.1.

Genome annotation databases

EnsemblBacteriaiABD82124; ABD82124; Sde_2867.
GeneIDi3968132.
KEGGisde:Sde_2867.
PATRICi23404830. VBISacDeg56404_3078.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000282 Genomic DNA. Translation: ABD82124.1 .
RefSeqi YP_528336.1. NC_007912.1.

3D structure databases

ProteinModelPortali Q21GQ5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 203122.Sde_2867.

Proteomic databases

PRIDEi Q21GQ5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD82124 ; ABD82124 ; Sde_2867 .
GeneIDi 3968132.
KEGGi sde:Sde_2867.
PATRICi 23404830. VBISacDeg56404_3078.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci SDEG203122:GI2M-2915-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2-40 / ATCC 43961 / DSM 17024.

Entry informationi

Entry nameiGLSA_SACD2
AccessioniPrimary (citable) accession number: Q21GQ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 18, 2006
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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