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Protein

Glutaminase

Gene

glsA

Organism
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei66SubstrateUniRule annotation1
Binding sitei116SubstrateUniRule annotation1
Binding sitei160SubstrateUniRule annotation1
Binding sitei167SubstrateUniRule annotation1
Binding sitei191SubstrateUniRule annotation1
Binding sitei243SubstrateUniRule annotation1
Binding sitei261Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:Sde_2867
OrganismiSaccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Taxonomic identifieri203122 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCellvibrionalesCellvibrionaceaeSaccharophagus
Proteomesi
  • UP000001947 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000483521 – 307GlutaminaseAdd BLAST307

Proteomic databases

PRIDEiQ21GQ5.

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi203122.Sde_2867.

Structurei

3D structure databases

ProteinModelPortaliQ21GQ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q21GQ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAIDYKKIF SEIVNELSSE DEKGSVATYI PELANVDPNK LGMHLTTVTN
60 70 80 90 100
QHFAYGDAEE AFSIQSIAKV WSLTLALKHL GADTWQRVGV EPSGTAFNSL
110 120 130 140 150
VQLEYEMGIP RNPFINAGAI VVCDILVSCL KNPKEDLLDF IRTSSGIPSI
160 170 180 190 200
EYCPVIAESE VKTGHRNYAL AHMMKGFGNI HNDVDCVLDL YFSLCSIKLT
210 220 230 240 250
CKQLAQAFLF LAAGGVNPAT QQQVITPKRT KRINSIMQMC GFYDEAGEFA
260 270 280 290 300
FKVGLPGKSG VGGGIVAVHP GKYCIAVFSP RLNASGNSVK AMKVLEALTT

KTELSIF
Length:307
Mass (Da):33,379
Last modified:April 18, 2006 - v1
Checksum:i93B71207B3CEC813
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000282 Genomic DNA. Translation: ABD82124.1.

Genome annotation databases

EnsemblBacteriaiABD82124; ABD82124; Sde_2867.
KEGGisde:Sde_2867.
PATRICi23404830. VBISacDeg56404_3078.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000282 Genomic DNA. Translation: ABD82124.1.

3D structure databases

ProteinModelPortaliQ21GQ5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203122.Sde_2867.

Proteomic databases

PRIDEiQ21GQ5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD82124; ABD82124; Sde_2867.
KEGGisde:Sde_2867.
PATRICi23404830. VBISacDeg56404_3078.

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_SACD2
AccessioniPrimary (citable) accession number: Q21GQ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 18, 2006
Last modified: November 2, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.