Q21GQ5 (GLSA_SACD2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutaminase
EC=3.5.1.2

Gene names

Name:	glsA
Ordered Locus Names:	Sde_2867

Organism

Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) [Complete proteome] [HAMAP]

Taxonomic identifier

203122 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Saccharophagus › Saccharophagus degradans

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the glutaminase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glutamine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 307	307	Glutaminase HAMAP-Rule MF_00313		PRO_1000048352
Sites
	Binding site	66	1	Substrate By similarity
	Binding site	116	1	Substrate By similarity
	Binding site	160	1	Substrate By similarity
	Binding site	167	1	Substrate By similarity
	Binding site	191	1	Substrate By similarity
	Binding site	243	1	Substrate By similarity
	Binding site	261	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q21GQ5 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 93B71207B3CEC813	FASTA	307	33,379
	10 20 30 40 50 60 MDAIDYKKIF SEIVNELSSE DEKGSVATYI PELANVDPNK LGMHLTTVTN QHFAYGDAEE 70 80 90 100 110 120 AFSIQSIAKV WSLTLALKHL GADTWQRVGV EPSGTAFNSL VQLEYEMGIP RNPFINAGAI 130 140 150 160 170 180 VVCDILVSCL KNPKEDLLDF IRTSSGIPSI EYCPVIAESE VKTGHRNYAL AHMMKGFGNI 190 200 210 220 230 240 HNDVDCVLDL YFSLCSIKLT CKQLAQAFLF LAAGGVNPAT QQQVITPKRT KRINSIMQMC 250 260 270 280 290 300 GFYDEAGEFA FKVGLPGKSG VGGGIVAVHP GKYCIAVFSP RLNASGNSVK AMKVLEALTT KTELSIF

References

[1]

"Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T." Weiner R.M., Taylor L.E. II, Henrissat B., Hauser L., Land M., Coutinho P.M., Rancurel C., Saunders E.H., Longmire A.G., Zhang H., Bayer E.A., Gilbert H.J., Larimer F., Zhulin I.B., Ekborg N.A., Lamed R., Richardson P.M., Borovok I., Hutcheson S. PLoS Genet. 4:E1000087-E1000087(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2-40 / ATCC 43961 / DSM 17024.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000282 Genomic DNA. Translation: ABD82124.1.
RefSeq	YP_528336.1. NC_007912.1.
3D structure databases
ProteinModelPortal	Q21GQ5.
ModBase	Search...
Protein-protein interaction databases
STRING	203122.Sde_2867.
Proteomic databases
PRIDE	Q21GQ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABD82124; ABD82124; Sde_2867.
GeneID	3968132.
KEGG	sde:Sde_2867.
PATRIC	23404830. VBISacDeg56404_3078.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2066.
HOGENOM	HOG000216890.
KO	K01425.
OMA	EPSGNPF.
ProtClustDB	PRK00971.
Enzyme and pathway databases
BioCyc	SDEG203122:GI2M-2917-MONOMER.
Family and domain databases
Gene3D	3.40.710.10. 1 hit.
HAMAP	MF_00313. Glutaminase.
InterPro	IPR012338. Beta-lactam/transpept-like. IPR015868. Glutaminase. [Graphical view]
PANTHER	PTHR12544. PTHR12544. 1 hit.
Pfam	PF04960. Glutaminase. 1 hit. [Graphical view]
SUPFAM	SSF56601. PBP_transp_fold. 1 hit.
TIGRFAMs	TIGR03814. Gln_ase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLSA_SACD2

Accession

Primary (citable) accession number: Q21GQ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 18, 2006
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program