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Q21DB5 (Q21DB5_RHOPB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase HAMAP MF_01123
Acyl-activating enzyme HAMAP MF_01123
Gene names
Name:acsA HAMAP MF_01123
Ordered Locus Names:RPC_0042
OrganismRhodopseudomonas palustris (strain BisB18) [Complete proteome] [HAMAP]
Taxonomic identifier316056 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length647 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5141 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6061N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
Q21DB5 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 31005F99ED1382AD

FASTA64772,131
        10         20         30         40         50         60 
MSEKIYDVSP EWAARAFIDD AKYQEMYARS VSDPNGFWGE QAQRIGWIKP FTKVEDTSFA 

        70         80         90        100        110        120 
PGHVSIKWFE DGVLNVAWNC IDRHLPDRAE QTAIIWEGDD PSESREISYR ELHDEVCKFA 

       130        140        150        160        170        180 
NILRSRNVQK GDRVTIYLPM IPEAAFAMLA CARIGAIHSV VFAGFSPDSL AQRITDCQSK 

       190        200        210        220        230        240 
IVITADEGLR GGRKVPLKAN VDAALKKCEG VDWVVVVKRT GADVFMDDVR DFWYAEAAEM 

       250        260        270        280        290        300 
VTTECPCEPM HAEDPLFILY TSGSTGQPKG VLHTSGGYLV FAAMTHQYVF DYHDGDIYWC 

       310        320        330        340        350        360 
TADVGWVTGH SYILYGPLAN GATTLMFEGV PNYPTNSRFW EVIDKHKVNI FYTAPTAIRA 

       370        380        390        400        410        420 
LMQGGDEPVK KTSRKSLRLL GSVGEPINPE AWEWYHRVIG EDRCPIVDTW WQTETGGILI 

       430        440        450        460        470        480 
TPLPGATKLK PGSATRPFFG VVPQILDAEA NVLEGECQGN LCLARSWPGQ MRTVYGDHAR 

       490        500        510        520        530        540 
FESTYFSAYP GKYFTGDGCR RDADGYYWIT GRVDDVINVS GHRMGTAEVE SSLVAHAKVS 

       550        560        570        580        590        600 
EAAVVGYPHD IKGQGIYAYV TLMDGTEPTE ELRKELVAWV RKDIGPIASP DLIQFAPSLP 

       610        620        630        640 
KTRSGKIMRR ILRKIAEDEP STLGDTSTLA DPAVVEDLVE HRQNKRV

« Hide

References

[1]"Complete sequence of Rhodopseudomonas palustris BisB18."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Pelletier D.A., Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BisB18.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000301 Genomic DNA. Translation: ABD85621.1.
RefSeqYP_529940.1. NC_007925.1.

3D structure databases

ProteinModelPortalQ21DB5.
SMRQ21DB5. Positions 13-643.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ21DB5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3971429.
GenomeReviewsGene locus RPC_0042 in contig CP000301_GR.
KEGGrpc:RPC_0042.
PATRIC23264655. VBIRhoPal29154_0045.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0365.
HOGENOMHBG547964.
OMATRGTEES.
PhylomeDBQ21DB5.
ProtClustDBPRK00174.

Enzyme and pathway databases

BioCycRPAL316056:RPC_0042-MONOMER.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ21DB5_RHOPB
AccessionPrimary (citable) accession number: Q21DB5
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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