Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Catalase-peroxidase

Gene

katG

Organism
Rhodopseudomonas palustris (strain BisB18)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.UniRule annotation

Catalytic activityi

Donor + H2O2 = oxidized donor + 2 H2O.UniRule annotation
2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

heme bUniRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei92Transition state stabilizerUniRule annotation1
Active sitei96Proton acceptorUniRule annotation1
Metal bindingi258Iron (heme axial ligand)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Protein family/group databases

PeroxiBasei3655. RpCP01_BisB18.

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-peroxidaseUniRule annotation (EC:1.11.1.21UniRule annotation)
Short name:
CPUniRule annotation
Alternative name(s):
Peroxidase/catalaseUniRule annotation
Gene namesi
Name:katGUniRule annotation
Ordered Locus Names:RPC_0361
OrganismiRhodopseudomonas palustris (strain BisB18)
Taxonomic identifieri316056 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001948 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003548941 – 732Catalase-peroxidaseAdd BLAST732

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki95 ↔ 217Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-243)UniRule annotation
Cross-linki217 ↔ 243Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-95)UniRule annotation

Post-translational modificationi

The covalent Trp-Tyr-Met adduct is important for the catalase, but not the peroxidase activity of the enzyme.UniRule annotation

Interactioni

Subunit structurei

Homodimer or homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi316056.RPC_0361.

Structurei

3D structure databases

ProteinModelPortaliQ21CF0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Peroxidase/catalase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
HOGENOMiHOG000218110.
KOiK03782.
OMAiYGATTMG.
OrthoDBiPOG091H05R1.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q21CF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAKTDDKAG KCPVAHGPAP RGNRDWWPEQ LNLSMLHQRS PSADPLGKDF
60 70 80 90 100
HYAEQFKTLD LKALKQDLTA LMTESQDWWP ADFGHYGGLF IRMAWHSAGT
110 120 130 140 150
YRTTDGRGGA GAGQQRFAPL NSWPDNANLD KARRLLWPIK QKYGQKISWA
160 170 180 190 200
DLYVLAGNVA LESMGFQTFG FAGGRADTWE PEELFWGPEG TWLGDERYSG
210 220 230 240 250
ERQLADPLGA VQMGLIYVNP EGPNGNPDPL GSAKDIRETF ARMAMNDEET
260 270 280 290 300
VALIAGGHTF GKTHGAGDPS LLGPEPEGGD VEDQGLGWKS KYGTGFGADA
310 320 330 340 350
ITGGPEVIWS QEPTKWSNHF FDNLFKFEWE LTKSPAGAQQ WVAKNAEPSV
360 370 380 390 400
PDPFDPSKKR LPTMLTSDLA LRFDPIYEKI SRRFYENPDE FADAFARAWF
410 420 430 440 450
KLTHRDMGPV ARYLGPEVPK ETLLWQDPIP PVDHELINDA DVEALKAKIL
460 470 480 490 500
GSGLSVADLV STAWNSASTF RGSDKRGGAN GARIRLAPQK DWEVNQPEQL
510 520 530 540 550
ATVLQKLEAI GKEFGKKVSL ADLIVLGGVA AIEKAAKDAG VAVKVPFSPG
560 570 580 590 600
RMDASQEQTD APSFAPLEPR ADGFRNYINS KKHQFMKPEE ALVDRAQLLT
610 620 630 640 650
LTAPEMTVLV GGLRVLGANA GDSKHGVFTT KPGTLSNDFF VNLLTMATSW
660 670 680 690 700
QPSGTEGIYE GRDRKSGEVK WTATRVDLIF GSHSQLRALA EVYAQADSKE
710 720 730
KFVNDFVAAW TKVMNADRFD LIAEPVLLEA AE
Length:732
Mass (Da):80,438
Last modified:April 18, 2006 - v1
Checksum:iF68B6F0CE5FE536C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000301 Genomic DNA. Translation: ABD85936.1.
RefSeqiWP_011470844.1. NC_007925.1.

Genome annotation databases

EnsemblBacteriaiABD85936; ABD85936; RPC_0361.
KEGGirpc:RPC_0361.
PATRICi23265314. VBIRhoPal29154_0370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000301 Genomic DNA. Translation: ABD85936.1.
RefSeqiWP_011470844.1. NC_007925.1.

3D structure databases

ProteinModelPortaliQ21CF0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi316056.RPC_0361.

Protein family/group databases

PeroxiBasei3655. RpCP01_BisB18.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD85936; ABD85936; RPC_0361.
KEGGirpc:RPC_0361.
PATRICi23265314. VBIRhoPal29154_0370.

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
HOGENOMiHOG000218110.
KOiK03782.
OMAiYGATTMG.
OrthoDBiPOG091H05R1.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKATG_RHOPB
AccessioniPrimary (citable) accession number: Q21CF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: April 18, 2006
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.