Q218E3 (CAPP_RHOPB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoenolpyruvate carboxylase
Short name=PEPC
Short name=PEPCase
EC=4.1.1.31

Gene names

Name:	ppc
Ordered Locus Names:	RPC_1684

Organism

Rhodopseudomonas palustris (strain BisB18) [Complete proteome] [HAMAP]

Taxonomic identifier

316056 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas › Rhodopseudomonas palustris

Protein attributes

Sequence length	929 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595
Cofactor	Magnesium By similarity. HAMAP-Rule MF_00595
Sequence similarities	Belongs to the PEPCase type 1 family.

Ontologies

Keywords
Biological process	Carbon dioxide fixation
Ligand	Magnesium
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbon fixation Inferred from electronic annotation. Source: HAMAP oxaloacetate metabolic process Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 929	929	Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595		PRO_1000025585
Sites
	Active site	162	1	By similarity
	Active site	591	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q218E3 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: F75692E00EA9B814	FASTA	929	103,875
	10 20 30 40 50 60 MSSKIMPIDP IAQKTPVAED PAAIDEDARL RDDIRLLGRI LGDTVRDQEG EGVFDVVERI 70 80 90 100 110 120 RQTSIRFHRD NDKPARSELE AILDGLSTPD TVRIVRAFSY FSHLANIAED QNNIRQMRAL 130 140 150 160 170 180 SGTPRPGSVV GTLAHARAVG ISAQELRRFF AHALVSPVLT AHPTEVRRKS TMDREMEVAG 190 200 210 220 230 240 LLDRRERLQM TAEEVAQHEE QLRRAVLTLW QTNMLRRTKL TVLDEVKNGL SFYDHSFLRE 250 260 270 280 290 300 VPRLHGLLED RLNDDDGRDE ELASFLRMGS WIGGDRDGNP FVTAEVMRGA LRLQSTRALR 310 320 330 340 350 360 FYLDELHALG SELSIAAHLA DVSDDLRLLA ERSPDTSPHR SGEPYRLAVS GIYARLAATA 370 380 390 400 410 420 HKLKFDDIRA PVGAAEPYAD PQEFKADLDV LHRSLIANQA SVIARGRLRQ LRRAVDCFGF 430 440 450 460 470 480 HLASLDMRQN SAVHERTMTE LIDAAMPGKS YMAMNEEARI ALLAGELRST RPLASPFVKY 490 500 510 520 530 540 GEETLGELAV FRTAAEAHAA FGHTVISQCI ISMCKGVSDM LEVVLLLKEV GLVDHAGRSA 550 560 570 580 590 600 INVVPLFETI EDLQASAGIM DRLLSLHDYR RLVDSRGGVQ EVMLGYSDSN KDGGFVTSGW 610 620 630 640 650 660 ELYKAEIELV KVFEHHGVRL RLFHGRGGSV GRGGGPSYDA ILAQPGGAVN GQIRITEQGE 670 680 690 700 710 720 IITSKYSNAE VGRNNLEILA AATLEASLLM PRQSAPRAEY LDAMEQLSSF AFKAYRGLVY 730 740 750 760 770 780 ETEGFEDYFW ASTVITEIAT LNIGSRPASR KKTHKIEDLR AIPWVFSWAQ CRLMLPGWYG 790 800 810 820 830 840 FGSAVEAFVK EHPDKGMAFL QELYREWPFF RTLLSNMDMV LAKSSIAIAS RYAELVPDEQ 850 860 870 880 890 900 LRQAIFGRIR AEWHGSIQAL LDIMQQDRLL QSNPRLERSI RNRFPYLDPL NHVQVELLKE 910 920 HRSHAIDEKV LRGIQLTING ISAGLRNSG

References

[1]

"Complete sequence of Rhodopseudomonas palustris BisB18." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Pelletier D.A., Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BisB18.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000301 Genomic DNA. Translation: ABD87243.1.
RefSeq	YP_531562.1. NC_007925.1.
3D structure databases
ProteinModelPortal	Q218E3.
ModBase	Search...
Protein-protein interaction databases
STRING	316056.RPC_1684.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABD87243; ABD87243; RPC_1684.
GeneID	3972744.
KEGG	rpc:RPC_1684.
PATRIC	23268062. VBIRhoPal29154_1730.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2352.
HOGENOM	HOG000238647.
KO	K01595.
OMA	AIPWVFG.
ProtClustDB	PRK00009.
Enzyme and pathway databases
BioCyc	RPAL316056:GH3E-1707-MONOMER.
Family and domain databases
HAMAP	MF_00595. PEPcase_type1.
InterPro	IPR021135. PEP_COase. IPR018129. PEP_COase_AS. IPR022805. PEP_COase_bac/pln-type. IPR015813. Pyrv/PenolPyrv_Kinase-like_dom. [Graphical view]
Pfam	PF00311. PEPcase. 1 hit. [Graphical view]
PRINTS	PR00150. PEPCARBXLASE.
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITE	PS00781. PEPCASE_1. 1 hit. PS00393. PEPCASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPP_RHOPB

Accession

Primary (citable) accession number: Q218E3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 18, 2006
Last modified:	May 29, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program