Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q218A1 (Q218A1_RHOPB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1 HAMAP MF_00191
EC=1.17.1.2 HAMAP MF_00191
Gene names
Name:ispH1 HAMAP MF_00191
Ordered Locus Names:RPC_1726
OrganismRhodopseudomonas palustris (strain BisB18) [Complete proteome] [HAMAP]
Taxonomic identifier316056 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00191 SAAS SAAS003451

Catalytic activity

Dimethylallyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Cofactor

Binds 1 3Fe-4S cluster By similarity. HAMAP MF_00191

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. HAMAP MF_00191 SAAS SAAS003451

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6. HAMAP MF_00191 SAAS SAAS003451

Sequence similarities

Belongs to the IspH family. HAMAP MF_00191

Sequences

Sequence LengthMass (Da)Tools
Q218A1 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: CABB254AACAE0F22

FASTA31433,642
        10         20         30         40         50         60 
MYNVRPLEVF LAQPRGFCAG VVRAIEIVER ALEKYGPPVY VRHEIVHNKY VVESLKAKGA 

        70         80         90        100        110        120 
IFVEDLSEVP PQAVTVFSAH GVARSVEEEA AARGLPVLNA TCPLVTKVHN QGKRYMSKGR 

       130        140        150        160        170        180 
ALILIGHAGH PEVVGTMGQV PGPVLLVQNV EDVAALTLPA DTPVAYITQT TLSVDDTKDI 

       190        200        210        220        230        240 
IAALAQRFSD IQGPDIRDIC YATQNRQSAV RDLSKLVDLI LVVGATNSSN SNRLREIGTE 

       250        260        270        280        290        300 
VGIPSYLIAD GSELNPDWLK GVKAVGITAG ASAPEVLVDD VIEALRRIGP VVVSVLPGRE 

       310 
ENIEFLLPAE LAPA

« Hide

References

[1]"Complete sequence of Rhodopseudomonas palustris BisB18."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Pelletier D.A., Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BisB18.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000301 Genomic DNA. Translation: ABD87285.1.
RefSeqYP_531604.1. NC_007925.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ218A1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3972379.
GenomeReviewsGene locus RPC_1726 in contig CP000301_GR.
KEGGrpc:RPC_1726.
PATRIC23268148. VBIRhoPal29154_1773.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0761.
HOGENOMHBG335228.
OMAHNQGKRY.
PhylomeDBQ218A1.
ProtClustDBPRK01045.

Enzyme and pathway databases

BioCycRPAL316056:RPC_1726-MONOMER.

Family and domain databases

HAMAPMF_00191. IspH.
[Tree]
InterProIPR003451. LytB.
[Graphical view]
KOK03527.
PfamPF02401. LYTB. 1 hit.
[Graphical view]
TIGRFAMsTIGR00216. IspH_lytB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ218A1_RHOPB
AccessionPrimary (citable) accession number: Q218A1
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info