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Q21743

- GST9_CAEEL

UniProt

Q21743 - GST9_CAEEL

Protein

Probable glutathione S-transferase 9

Gene

gst-9

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.By similarity

    Catalytic activityi

    RX + glutathione = HX + R-S-glutathione.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei8 – 81GlutathioneBy similarity
    Binding sitei39 – 391GlutathioneBy similarity
    Binding sitei43 – 431GlutathioneBy similarity

    GO - Molecular functioni

    1. glutathione transferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glutathione S-transferase 9 (EC:2.5.1.18)
    Alternative name(s):
    GST class-sigma
    Gene namesi
    Name:gst-9
    ORF Names:R05F9.5
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome II

    Organism-specific databases

    WormBaseiR05F9.5; CE04807; WBGene00001757; gst-9.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 206206Probable glutathione S-transferase 9PRO_0000185932Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.R05F9.5.

    Structurei

    3D structure databases

    ProteinModelPortaliQ21743.
    SMRiQ21743. Positions 1-204.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 7978GST N-terminalAdd
    BLAST
    Domaini81 – 206126GST C-terminalAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni50 – 512Glutathione bindingBy similarity
    Regioni63 – 642Glutathione bindingBy similarity

    Sequence similaritiesi

    Belongs to the GST superfamily. Sigma family.Curated
    Contains 1 GST C-terminal domain.Curated
    Contains 1 GST N-terminal domain.Curated

    Phylogenomic databases

    eggNOGiNOG276829.
    GeneTreeiENSGT00670000097856.
    HOGENOMiHOG000115733.
    InParanoidiQ21743.
    OMAiLESAWID.
    OrthoDBiEOG78WKT1.
    PhylomeDBiQ21743.

    Family and domain databases

    Gene3Di1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProiIPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view]
    PfamiPF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEiPS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q21743-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVSYKLIYFQ SRGNGEIARQ VFAFAGQEFI DERISKEQWA EIKNMTPFGQ    50
    VPVLEVDGRQ LAQSITIVRY LSKQFGISGK SSWEEAQVDA LGDQFKDYRV 100
    EARPFFRAKM GFSDGDVDQL YKDLFVPAFN KMYSIFTESL KSSGSGFLVG 150
    DSLTWMDLAI AQHSADLLEA DGKILDTFLE MKDHQKKIHS IPNVKKWIEK 200
    RPVTSR 206
    Length:206
    Mass (Da):23,537
    Last modified:November 1, 1996 - v1
    Checksum:i3C4B2ADC081970D4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FO081120 Genomic DNA. Translation: CCD69273.1.
    PIRiT16683.
    T16685.
    RefSeqiNP_001022266.1. NM_001027095.1.
    UniGeneiCel.14654.

    Genome annotation databases

    EnsemblMetazoaiR05F9.5; R05F9.5; WBGene00001757.
    GeneIDi187615.
    KEGGicel:CELE_R05F9.5.
    UCSCiR05F9.5. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FO081120 Genomic DNA. Translation: CCD69273.1 .
    PIRi T16683.
    T16685.
    RefSeqi NP_001022266.1. NM_001027095.1.
    UniGenei Cel.14654.

    3D structure databases

    ProteinModelPortali Q21743.
    SMRi Q21743. Positions 1-204.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.R05F9.5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai R05F9.5 ; R05F9.5 ; WBGene00001757 .
    GeneIDi 187615.
    KEGGi cel:CELE_R05F9.5.
    UCSCi R05F9.5. c. elegans.

    Organism-specific databases

    CTDi 187615.
    WormBasei R05F9.5 ; CE04807 ; WBGene00001757 ; gst-9.

    Phylogenomic databases

    eggNOGi NOG276829.
    GeneTreei ENSGT00670000097856.
    HOGENOMi HOG000115733.
    InParanoidi Q21743.
    OMAi LESAWID.
    OrthoDBi EOG78WKT1.
    PhylomeDBi Q21743.

    Miscellaneous databases

    NextBioi 935874.

    Family and domain databases

    Gene3Di 1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProi IPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view ]
    Pfami PF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEi PS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiGST9_CAEEL
    AccessioniPrimary (citable) accession number: Q21743
    Secondary accession number(s): Q21744
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 28, 2003
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3