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Protein

Probable glutathione S-transferase 9

Gene

gst-9

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei8GlutathioneBy similarity1
Binding sitei39GlutathioneBy similarity1
Binding sitei43GlutathioneBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionTransferase

Enzyme and pathway databases

ReactomeiR-CEL-156590 Glutathione conjugation
R-CEL-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX)

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutathione S-transferase 9 (EC:2.5.1.18)
Alternative name(s):
GST class-sigma
Gene namesi
Name:gst-9
ORF Names:R05F9.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiR05F9.5 ; CE04807 ; WBGene00001757 ; gst-9

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001859321 – 206Probable glutathione S-transferase 9Add BLAST206

Proteomic databases

PaxDbiQ21743
PeptideAtlasiQ21743
PRIDEiQ21743

Expressioni

Gene expression databases

BgeeiWBGene00001757

Interactioni

Protein-protein interaction databases

STRINGi6239.R05F9.5

Structurei

3D structure databases

ProteinModelPortaliQ21743
SMRiQ21743
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 79GST N-terminalAdd BLAST78
Domaini81 – 206GST C-terminalAdd BLAST126

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni49 – 51Glutathione bindingBy similarity3
Regioni63 – 64Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Sigma family.Curated

Phylogenomic databases

eggNOGiKOG1695 Eukaryota
ENOG4111VAU LUCA
GeneTreeiENSGT00670000097856
HOGENOMiHOG000115733
InParanoidiQ21743
KOiK04097
OMAiRIHDIPN
OrthoDBiEOG091G0MBB
PhylomeDBiQ21743

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF14497 GST_C_3, 1 hit
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q21743-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSYKLIYFQ SRGNGEIARQ VFAFAGQEFI DERISKEQWA EIKNMTPFGQ
60 70 80 90 100
VPVLEVDGRQ LAQSITIVRY LSKQFGISGK SSWEEAQVDA LGDQFKDYRV
110 120 130 140 150
EARPFFRAKM GFSDGDVDQL YKDLFVPAFN KMYSIFTESL KSSGSGFLVG
160 170 180 190 200
DSLTWMDLAI AQHSADLLEA DGKILDTFLE MKDHQKKIHS IPNVKKWIEK

RPVTSR
Length:206
Mass (Da):23,537
Last modified:November 1, 1996 - v1
Checksum:i3C4B2ADC081970D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081120 Genomic DNA Translation: CCD69273.1
PIRiT16683
T16685
RefSeqiNP_001022266.1, NM_001027095.1
UniGeneiCel.14654

Genome annotation databases

EnsemblMetazoaiR05F9.5; R05F9.5; WBGene00001757
GeneIDi187615
KEGGicel:CELE_R05F9.5
UCSCiR05F9.5 c. elegans

Similar proteinsi

Entry informationi

Entry nameiGST9_CAEEL
AccessioniPrimary (citable) accession number: Q21743
Secondary accession number(s): Q21744
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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