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Q21743 (GST9_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glutathione S-transferase 9

EC=2.5.1.18
Alternative name(s):
GST class-sigma
Gene names
Name:gst-9
ORF Names:R05F9.5
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length206 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles By similarity. UniProtKB P46436

Catalytic activity

RX + glutathione = HX + R-S-glutathione. UniProtKB P46436

Sequence similarities

Belongs to the GST superfamily. Sigma family. UniProtKB P46436

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 206206Probable glutathione S-transferase 9
PRO_0000185932

Regions

Domain2 – 7978GST N-terminal
Domain81 – 206126GST C-terminal
Region50 – 512Glutathione binding By similarity
Region63 – 642Glutathione binding By similarity

Sites

Binding site81Glutathione By similarity
Binding site391Glutathione By similarity
Binding site431Glutathione By similarity

Sequences

Sequence LengthMass (Da)Tools
Q21743 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 3C4B2ADC081970D4

FASTA20623,537
        10         20         30         40         50         60 
MVSYKLIYFQ SRGNGEIARQ VFAFAGQEFI DERISKEQWA EIKNMTPFGQ VPVLEVDGRQ 

        70         80         90        100        110        120 
LAQSITIVRY LSKQFGISGK SSWEEAQVDA LGDQFKDYRV EARPFFRAKM GFSDGDVDQL 

       130        140        150        160        170        180 
YKDLFVPAFN KMYSIFTESL KSSGSGFLVG DSLTWMDLAI AQHSADLLEA DGKILDTFLE 

       190        200 
MKDHQKKIHS IPNVKKWIEK RPVTSR 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FO081120 Genomic DNA. Translation: CCD69273.1.
PIRT16683.
T16685.
RefSeqNP_001022266.1. NM_001027095.1.
UniGeneCel.14654.

3D structure databases

ProteinModelPortalQ21743.
SMRQ21743. Positions 1-204.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6239.R05F9.5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaR05F9.5; R05F9.5; WBGene00001757.
GeneID187615.
KEGGcel:CELE_R05F9.5.
UCSCR05F9.5. c. elegans.

Organism-specific databases

CTD187615.
WormBaseR05F9.5; CE04807; WBGene00001757; gst-9.

Phylogenomic databases

eggNOGNOG276829.
GeneTreeENSGT00670000097856.
HOGENOMHOG000115733.
InParanoidQ21743.
OMALESAWID.
OrthoDBEOG78WKT1.
PhylomeDBQ21743.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio935874.

Entry information

Entry nameGST9_CAEEL
AccessionPrimary (citable) accession number: Q21743
Secondary accession number(s): Q21744
Entry history
Integrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase