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Q21743

- GST9_CAEEL

UniProt

Q21743 - GST9_CAEEL

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Protein

Probable glutathione S-transferase 9

Gene
gst-9, R05F9.5
Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles By similarity.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei8 – 81Glutathione By similarity
Binding sitei39 – 391Glutathione By similarity
Binding sitei43 – 431Glutathione By similarity

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutathione S-transferase 9 (EC:2.5.1.18)
Alternative name(s):
GST class-sigma
Gene namesi
Name:gst-9
ORF Names:R05F9.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome II

Organism-specific databases

WormBaseiR05F9.5; CE04807; WBGene00001757; gst-9.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 206206Probable glutathione S-transferase 9PRO_0000185932Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi6239.R05F9.5.

Structurei

3D structure databases

ProteinModelPortaliQ21743.
SMRiQ21743. Positions 1-204.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 7978GST N-terminalAdd
BLAST
Domaini81 – 206126GST C-terminalAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni50 – 512Glutathione binding By similarity
Regioni63 – 642Glutathione binding By similarity

Sequence similaritiesi

Belongs to the GST superfamily. Sigma family.By similarity

Phylogenomic databases

eggNOGiNOG276829.
GeneTreeiENSGT00670000097856.
HOGENOMiHOG000115733.
InParanoidiQ21743.
OMAiLESAWID.
OrthoDBiEOG78WKT1.
PhylomeDBiQ21743.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q21743-1 [UniParc]FASTAAdd to Basket

« Hide

MVSYKLIYFQ SRGNGEIARQ VFAFAGQEFI DERISKEQWA EIKNMTPFGQ    50
VPVLEVDGRQ LAQSITIVRY LSKQFGISGK SSWEEAQVDA LGDQFKDYRV 100
EARPFFRAKM GFSDGDVDQL YKDLFVPAFN KMYSIFTESL KSSGSGFLVG 150
DSLTWMDLAI AQHSADLLEA DGKILDTFLE MKDHQKKIHS IPNVKKWIEK 200
RPVTSR 206
Length:206
Mass (Da):23,537
Last modified:November 1, 1996 - v1
Checksum:i3C4B2ADC081970D4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO081120 Genomic DNA. Translation: CCD69273.1.
PIRiT16683.
T16685.
RefSeqiNP_001022266.1. NM_001027095.1.
UniGeneiCel.14654.

Genome annotation databases

EnsemblMetazoaiR05F9.5; R05F9.5; WBGene00001757.
GeneIDi187615.
KEGGicel:CELE_R05F9.5.
UCSCiR05F9.5. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO081120 Genomic DNA. Translation: CCD69273.1 .
PIRi T16683.
T16685.
RefSeqi NP_001022266.1. NM_001027095.1.
UniGenei Cel.14654.

3D structure databases

ProteinModelPortali Q21743.
SMRi Q21743. Positions 1-204.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6239.R05F9.5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai R05F9.5 ; R05F9.5 ; WBGene00001757 .
GeneIDi 187615.
KEGGi cel:CELE_R05F9.5.
UCSCi R05F9.5. c. elegans.

Organism-specific databases

CTDi 187615.
WormBasei R05F9.5 ; CE04807 ; WBGene00001757 ; gst-9.

Phylogenomic databases

eggNOGi NOG276829.
GeneTreei ENSGT00670000097856.
HOGENOMi HOG000115733.
InParanoidi Q21743.
OMAi LESAWID.
OrthoDBi EOG78WKT1.
PhylomeDBi Q21743.

Miscellaneous databases

NextBioi 935874.

Family and domain databases

Gene3Di 1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProi IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view ]
SUPFAMi SSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEi PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiGST9_CAEEL
AccessioniPrimary (citable) accession number: Q21743
Secondary accession number(s): Q21744
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi