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Q21706 (UGT47_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative UDP-glucuronosyltransferase ugt-47

Short name=UDPGT 47
EC=2.4.1.17
Gene names
Name:ugt-47
ORF Names:R04B5.9
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length536 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. UniProtKB Q9BY64

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the UDP-glycosyltransferase family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal
Transmembrane
Transmembrane helix
   Molecular functionGlycosyltransferase
Transferase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionglucuronosyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 536515Putative UDP-glucuronosyltransferase ugt-47
PRO_0000396643

Regions

Transmembrane497 – 51721Helical; Potential

Amino acid modifications

Glycosylation521N-linked (GlcNAc...) Ref.2
Glycosylation3081N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q21706 [UniParc].

Last modified March 1, 2005. Version 2.
Checksum: F83E5FCD6A3690EE

FASTA53661,449
        10         20         30         40         50         60 
MFRYHSILLL AILYFFEYGL AYKILVFSPA TSKSHLISNG RIADELAKAG HNVTLLEIDF 

        70         80         90        100        110        120 
LGIVDSTKSA KLVKKTIVRV PKKMQGFKNV IQSFSEGVME DEGLFELLKG NIAYQTVYND 

       130        140        150        160        170        180 
LCEEFLENEV MFNKLKDENF DAFFAEQLNI CGFGYAKALG IQRKFLISSC PFFSHVYDYT 

       190        200        210        220        230        240 
SHPAPYASVP FISDMSPEPT YLERTNNLLR GITINTFFYF SHNRLTSIFR KKFGDDFPAI 

       250        260        270        280        290        300 
TEIVRNVDII FLATDEIIDF SSPTLPNLVH VGGLGVDDDT TEMGPVFEAE MKKGDKGVIY 

       310        320        330        340        350        360 
FSLGTIANTS TIDKKVMESF LEIVKKFPDY HFLIRADKND KNTKDKATEI SNVFVSDWLP 

       370        380        390        400        410        420 
QPAILHHPRL RTFITHAGYN GLMEAALAGV PLITIPFMFD QNLNSRAIEK KGWGIRRDKK 

       430        440        450        460        470        480 
QFLTEPNAIE EAIREMLTNP SYTKQAHRVR DLMRNKPMGA RDRFIKTTEW VIQNGGVHEL 

       490        500        510        520        530 
LTEGRDLSII KYYNLDIIVP CFFVAFYFII FPFFKLFGGF YYYSCFGHIE SKYKKD 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
[2]"Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis elegans and suggests an atypical translocation mechanism for integral membrane proteins."
Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T., Taoka M., Takahashi N., Isobe T.
Mol. Cell. Proteomics 6:2100-2109(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-52, IDENTIFICATION BY MASS SPECTROMETRY.
Strain: Bristol N2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z70782 Genomic DNA. Translation: CAA94845.2.
PIRT23893.
RefSeqNP_505595.2. NM_073194.4.
UniGeneCel.25018.

3D structure databases

ProteinModelPortalQ21706.
SMRQ21706. Positions 33-59, 176-453.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6239.R04B5.9.

Protein family/group databases

CAZyGT1. Glycosyltransferase Family 1.

Proteomic databases

PaxDbQ21706.
PRIDEQ21706.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaR04B5.9; R04B5.9; R04B5.9.
GeneID187570.
KEGGcel:CELE_R04B5.9.
UCSCR04B5.9. c. elegans.

Organism-specific databases

CTD187570.
WormBaseR04B5.9; CE37984; WBGene00011006; ugt-47.

Phylogenomic databases

eggNOGNOG326467.
HOGENOMHOG000018977.
InParanoidQ21706.
OMANSRAIEK.
OrthoDBEOG78H3T2.
PhylomeDBQ21706.

Family and domain databases

InterProIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERPTHR11926. PTHR11926. 1 hit.
PfamPF00201. UDPGT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio935730.

Entry information

Entry nameUGT47_CAEEL
AccessionPrimary (citable) accession number: Q21706
Entry history
Integrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: March 1, 2005
Last modified: April 16, 2014
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase