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Q215B4 (TPIS_RHOPB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Triosephosphate isomerase
Short name=TIM
EC=5.3.1.1
Alternative name(s):
Triose-phosphate isomerase
Gene names
Name:tpiA
Ordered Locus Names:RPC_2471
OrganismRhodopseudomonas palustris (strain BisB18) [Complete proteome] [HAMAP]
Taxonomic identifier316056 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glyceraldehyde 3-phosphate = glycerone phosphate. HAMAP MF_00147_B

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00147_B

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1. HAMAP MF_00147_B

Subunit structure

Homodimer By similarity. HAMAP MF_00147_B

Subcellular location

Cytoplasm By similarity HAMAP MF_00147_B.

Sequence similarities

Belongs to the triosephosphate isomerase family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
Pentose shunt
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiontriose-phosphate isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 257257Triosephosphate isomerase HAMAP MF_00147_B
PRO_0000307547

Sites

Active site1041Electrophile By similarity
Active site1741Proton acceptor By similarity
Binding site121Substrate By similarity
Binding site141Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q215B4 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: DD7345663943631B

FASTA25726,113
        10         20         30         40         50         60 
MSAAIRPLIA GNWKMNGLRA SLSELKLMLE GAGKLSATAD LLICPPATLV AAFAQKLAAD 

        70         80         90        100        110        120 
TGSRSNSFAI GAQDCHPRAS GAHTGDISAE MLADAGASAV IVGHSERRAD HGESDALVRE 

       130        140        150        160        170        180 
KAEAAWRAGL VAIICVGETQ GQRDAGQTLD VVGTQLAGSL PDGATAANTV VAYEPVWAIG 

       190        200        210        220        230        240 
TGRTPTVADV EQVHGFIRKS LTQRMSGEGS KVRILYGGSV KPSNAQELMA VADVNGALVG 

       250 
GASLKAGDFL AIAAGCP

« Hide

References

[1]"Complete sequence of Rhodopseudomonas palustris BisB18."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Pelletier D.A., Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BisB18.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000301 Genomic DNA. Translation: ABD88022.1.
RefSeqYP_532341.1. NC_007925.1.

3D structure databases

ProteinModelPortalQ215B4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ215B4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3971362.
GenomeReviewsGene locus RPC_2471 in contig CP000301_GR.
KEGGrpc:RPC_2471.
PATRIC23269682. VBIRhoPal29154_2537.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0149.
HOGENOMHBG708281.
OMAVCVGETQ.
PhylomeDBQ215B4.
ProtClustDBPRK00042.

Enzyme and pathway databases

BioCycRPAL316056:RPC_2471-MONOMER.

Family and domain databases

HAMAPMF_00147_B. TIM_B.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR022896. TrioseP_Isoase_bac/euk.
IPR000652. Triosephosphate_isomerase.
IPR020861. Triosephosphate_isomerase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01803.
PANTHERPTHR21139. Triophos_ismrse. 1 hit.
PfamPF00121. TIM. 1 hit.
[Graphical view]
SUPFAMSSF51351. Triophos_ismrse. 1 hit.
TIGRFAMsTIGR00419. Tim. 1 hit.
PROSITEPS00171. TIM_1. 1 hit.
PS51440. TIM_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTPIS_RHOPB
AccessionPrimary (citable) accession number: Q215B4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: April 18, 2006
Last modified: January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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