ID   Q21592_CAEEL            Unreviewed;       516 AA.
AC   Q21592;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 2.
DT   27-MAR-2024, entry version 178.
DE   RecName: Full=Kinesin light chain {ECO:0000256|RuleBase:RU367020};
GN   Name=klc-1 {ECO:0000313|EMBL:CAA92746.2, ECO:0000313|WormBase:M7.2a};
GN   ORFNames=CELE_M7.2 {ECO:0000313|EMBL:CAA92746.2}, M7.2
GN   {ECO:0000313|WormBase:M7.2a};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239 {ECO:0000313|EMBL:CAA92746.2, ECO:0000313|Proteomes:UP000001940};
RN   [1] {ECO:0000313|EMBL:CAA92746.2, ECO:0000313|Proteomes:UP000001940}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2 {ECO:0000313|EMBL:CAA92746.2,
RC   ECO:0000313|Proteomes:UP000001940};
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RA   Sulson J.E., Waterston R.;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Kinesin is a microtubule-associated force-producing protein
CC       that play a role in organelle transport.
CC       {ECO:0000256|RuleBase:RU367020}.
CC   -!- SUBUNIT: Oligomeric complex composed of two heavy chains and two light
CC       chains. {ECO:0000256|RuleBase:RU367020}.
CC   -!- INTERACTION:
CC       Q21592; Q9TZK8: meg-4; NbExp=3; IntAct=EBI-316831, EBI-314126;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU367020}.
CC   -!- SIMILARITY: Belongs to the kinesin light chain family.
CC       {ECO:0000256|ARBA:ARBA00009622, ECO:0000256|RuleBase:RU367020}.
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DR   EMBL; BX284604; CAA92746.2; -; Genomic_DNA.
DR   PIR; C88827; C88827.
DR   PIR; T23827; T23827.
DR   RefSeq; NP_001255535.1; NM_001268606.1.
DR   AlphaFoldDB; Q21592; -.
DR   SMR; Q21592; -.
DR   DIP; DIP-26939N; -.
DR   IntAct; Q21592; 3.
DR   EPD; Q21592; -.
DR   PeptideAtlas; Q21592; -.
DR   EnsemblMetazoa; M7.2a.1; M7.2a.1; WBGene00002214.
DR   GeneID; 178007; -.
DR   AGR; WB:WBGene00002214; -.
DR   WormBase; M7.2a; CE23882; WBGene00002214; klc-1.
DR   GeneTree; ENSGT00940000155555; -.
DR   HOGENOM; CLU_019953_0_0_1; -.
DR   OrthoDB; 5392083at2759; -.
DR   PhylomeDB; Q21592; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00002214; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR   ExpressionAtlas; Q21592; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005871; C:kinesin complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR   GO; GO:0019894; F:kinesin binding; IBA:GO_Central.
DR   GO; GO:0051295; P:establishment of meiotic spindle localization; IMP:WormBase.
DR   GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR   GO; GO:0040038; P:polar body extrusion after meiotic divisions; IMP:WormBase.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR002151; Kinesin_light.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR45783; KINESIN LIGHT CHAIN; 1.
DR   PANTHER; PTHR45783:SF3; KINESIN LIGHT CHAIN; 1.
DR   Pfam; PF13424; TPR_12; 2.
DR   Pfam; PF13176; TPR_7; 1.
DR   PRINTS; PR00381; KINESINLIGHT.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50005; TPR; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|RuleBase:RU367020};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW   ECO:0000256|RuleBase:RU367020};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU367020};
KW   Motor protein {ECO:0000256|ARBA:ARBA00023175,
KW   ECO:0000256|RuleBase:RU367020};
KW   Proteomics identification {ECO:0007829|EPD:Q21592,
KW   ECO:0007829|PeptideAtlas:Q21592};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}.
FT   REPEAT          327..360
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          474..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          108..135
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        477..494
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   516 AA;  58070 MW;  2636215BD9CA344D CRC64;
     MVISLGDDIT TVLKTVQQTL FALRDEHEAA TRILEANLIN SDSSEPSLPS EKMGLIDESL
     GKVMDGGDEA SLLIMMDKLM QSYDVQLSKN HESIRLLRQE NTWLLDELTT TQRKLQESER
     TVAHLEEERD HYKFQDSMNY LNSDFQHTTS VDATPMMVDT LQELGFGPEE EDQNNNQADQ
     GCRSSSFSNP ISNDYQLPTR LQTLQNLVIQ YMEQGRFEVA IPLCKQALED VVKVHGNVHL
     DVATMLNVLA IVYRNQENFK DAAIYLEKAL SIRVQCCGEN HHSVAATLNN LAIAYGKRGK
     YKESEPLCKR ALEIRKNLLG PNHPDVAKQL TNLGIVTQQL EKYEETENYF KQALSIYNRA
     FPENHQNVIK TKNQLASVFL KQGKYQEAEE MYKNILSKVA ITGNKPIWRI AEDREERQRN
     GIPKVDDESF NVNPTTVMDS NVMSTIKNLA AVYRKQGKEE AAGTLEEALG AKKQINGGAD
     HTNSTASSVE TSSAVAINPA QSGIKKRIMH FVGLNF
//