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Q21592

- Q21592_CAEEL

UniProt

Q21592 - Q21592_CAEEL

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Protein
Submitted name:

Protein KLC-1, isoform a

Gene

klc-1

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. microtubule motor activity Source: InterPro

GO - Biological processi

  1. establishment of meiotic spindle localization Source: WormBase
  2. polar body extrusion after meiotic divisions Source: WormBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein KLC-1, isoform aImported
Gene namesi
Name:klc-1Imported
ORF Names:CELE_M7.2Imported, M7.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome IV

Organism-specific databases

WormBaseiM7.2a; CE23882; WBGene00002214; klc-1.

Subcellular locationi

GO - Cellular componenti

  1. kinesin complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ21592.
PRIDEiQ21592.

Expressioni

Gene expression databases

ExpressionAtlasiQ21592. baseline.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CELE_C36C9.1Q9TZK83EBI-316831,EBI-314126

Protein-protein interaction databases

DIPiDIP-26939N.
IntActiQ21592. 3 interactions.
MINTiMINT-251335.
STRINGi6239.M7.2.

Structurei

3D structure databases

ProteinModelPortaliQ21592.
SMRiQ21592. Positions 195-458.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

RepeatUniRule annotation, TPR repeatUniRule annotation

Phylogenomic databases

eggNOGiCOG0457.
GeneTreeiENSGT00390000006393.
HOGENOMiHOG000261663.
PhylomeDBiQ21592.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR002151. Kinesin_light.
IPR015390. Rabaptin_Rab5-bd_dom.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR013105. TPR_2.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF09311. Rab5-bind. 1 hit.
PF00515. TPR_1. 1 hit.
PF07719. TPR_2. 1 hit.
[Graphical view]
PRINTSiPR00381. KINESINLIGHT.
SMARTiSM00028. TPR. 4 hits.
[Graphical view]
PROSITEiPS50005. TPR. 4 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q21592-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVISLGDDIT TVLKTVQQTL FALRDEHEAA TRILEANLIN SDSSEPSLPS
60 70 80 90 100
EKMGLIDESL GKVMDGGDEA SLLIMMDKLM QSYDVQLSKN HESIRLLRQE
110 120 130 140 150
NTWLLDELTT TQRKLQESER TVAHLEEERD HYKFQDSMNY LNSDFQHTTS
160 170 180 190 200
VDATPMMVDT LQELGFGPEE EDQNNNQADQ GCRSSSFSNP ISNDYQLPTR
210 220 230 240 250
LQTLQNLVIQ YMEQGRFEVA IPLCKQALED VVKVHGNVHL DVATMLNVLA
260 270 280 290 300
IVYRNQENFK DAAIYLEKAL SIRVQCCGEN HHSVAATLNN LAIAYGKRGK
310 320 330 340 350
YKESEPLCKR ALEIRKNLLG PNHPDVAKQL TNLGIVTQQL EKYEETENYF
360 370 380 390 400
KQALSIYNRA FPENHQNVIK TKNQLASVFL KQGKYQEAEE MYKNILSKVA
410 420 430 440 450
ITGNKPIWRI AEDREERQRN GIPKVDDESF NVNPTTVMDS NVMSTIKNLA
460 470 480 490 500
AVYRKQGKEE AAGTLEEALG AKKQINGGAD HTNSTASSVE TSSAVAINPA
510
QSGIKKRIMH FVGLNF
Length:516
Mass (Da):58,070
Last modified:May 1, 2000 - v2
Checksum:i2636215BD9CA344D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68337 Genomic DNA. Translation: CAA92746.2.
PIRiC88827.
T23827.
RefSeqiNP_001255535.1. NM_001268606.1.
UniGeneiCel.12595.

Genome annotation databases

EnsemblMetazoaiM7.2a; M7.2a; WBGene00002214.
GeneIDi178007.
KEGGicel:CELE_M7.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68337 Genomic DNA. Translation: CAA92746.2 .
PIRi C88827.
T23827.
RefSeqi NP_001255535.1. NM_001268606.1.
UniGenei Cel.12595.

3D structure databases

ProteinModelPortali Q21592.
SMRi Q21592. Positions 195-458.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-26939N.
IntActi Q21592. 3 interactions.
MINTi MINT-251335.
STRINGi 6239.M7.2.

Proteomic databases

PaxDbi Q21592.
PRIDEi Q21592.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai M7.2a ; M7.2a ; WBGene00002214 .
GeneIDi 178007.
KEGGi cel:CELE_M7.2.

Organism-specific databases

CTDi 178007.
WormBasei M7.2a ; CE23882 ; WBGene00002214 ; klc-1.

Phylogenomic databases

eggNOGi COG0457.
GeneTreei ENSGT00390000006393.
HOGENOMi HOG000261663.
PhylomeDBi Q21592.

Miscellaneous databases

NextBioi 899338.

Gene expression databases

ExpressionAtlasi Q21592. baseline.

Family and domain databases

Gene3Di 1.25.40.10. 1 hit.
InterProi IPR002151. Kinesin_light.
IPR015390. Rabaptin_Rab5-bd_dom.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR013105. TPR_2.
IPR019734. TPR_repeat.
[Graphical view ]
Pfami PF09311. Rab5-bind. 1 hit.
PF00515. TPR_1. 1 hit.
PF07719. TPR_2. 1 hit.
[Graphical view ]
PRINTSi PR00381. KINESINLIGHT.
SMARTi SM00028. TPR. 4 hits.
[Graphical view ]
PROSITEi PS50005. TPR. 4 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ21592_CAEEL
AccessioniPrimary (citable) accession number: Q21592
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3