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Protein
Submitted name:

Kinesin Light Chain

Gene

klc-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • establishment of meiotic spindle localization Source: WormBase
  • polar body extrusion after meiotic divisions Source: WormBase

Enzyme and pathway databases

ReactomeiR-CEL-5624138. Trafficking of myristoylated proteins to the cilium.
R-CEL-983189. Kinesins.

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin Light ChainImported
Gene namesi
Name:klc-1Imported
ORF Names:CELE_M7.2Imported, M7.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiM7.2a; CE23882; WBGene00002214; klc-1.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

EPDiQ21592.
PaxDbiQ21592.
PeptideAtlasiQ21592.

Expressioni

Gene expression databases

BgeeiWBGene00002214.
ExpressionAtlasiQ21592. baseline and differential.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
meg-4Q9TZK83EBI-316831,EBI-314126

Protein-protein interaction databases

DIPiDIP-26939N.
IntActiQ21592. 3 interactors.
MINTiMINT-251335.
STRINGi6239.M7.2.

Structurei

3D structure databases

ProteinModelPortaliQ21592.
SMRiQ21592.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini243 – 402TPR_REGIONInterPro annotationAdd BLAST160
Repeati243 – 276TPRPROSITE-ProRule annotationAdd BLAST34
Repeati285 – 318TPRPROSITE-ProRule annotationAdd BLAST34
Repeati327 – 360TPRPROSITE-ProRule annotationAdd BLAST34
Repeati369 – 402TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili108 – 135Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1840. Eukaryota.
COG0457. LUCA.
GeneTreeiENSGT00390000006393.
HOGENOMiHOG000261663.
PhylomeDBiQ21592.

Family and domain databases

Gene3Di1.10.10.10. 4 hits.
InterProiView protein in InterPro
IPR002151. Kinesin_light.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
IPR011991. WHTH_DNA-bd_dom.
PRINTSiPR00381. KINESINLIGHT.
SMARTiView protein in SMART
SM00028. TPR. 4 hits.
SUPFAMiSSF48452. SSF48452. 3 hits.
PROSITEiView protein in PROSITE
PS50005. TPR. 4 hits.
PS50293. TPR_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

Q21592-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVISLGDDIT TVLKTVQQTL FALRDEHEAA TRILEANLIN SDSSEPSLPS
60 70 80 90 100
EKMGLIDESL GKVMDGGDEA SLLIMMDKLM QSYDVQLSKN HESIRLLRQE
110 120 130 140 150
NTWLLDELTT TQRKLQESER TVAHLEEERD HYKFQDSMNY LNSDFQHTTS
160 170 180 190 200
VDATPMMVDT LQELGFGPEE EDQNNNQADQ GCRSSSFSNP ISNDYQLPTR
210 220 230 240 250
LQTLQNLVIQ YMEQGRFEVA IPLCKQALED VVKVHGNVHL DVATMLNVLA
260 270 280 290 300
IVYRNQENFK DAAIYLEKAL SIRVQCCGEN HHSVAATLNN LAIAYGKRGK
310 320 330 340 350
YKESEPLCKR ALEIRKNLLG PNHPDVAKQL TNLGIVTQQL EKYEETENYF
360 370 380 390 400
KQALSIYNRA FPENHQNVIK TKNQLASVFL KQGKYQEAEE MYKNILSKVA
410 420 430 440 450
ITGNKPIWRI AEDREERQRN GIPKVDDESF NVNPTTVMDS NVMSTIKNLA
460 470 480 490 500
AVYRKQGKEE AAGTLEEALG AKKQINGGAD HTNSTASSVE TSSAVAINPA
510
QSGIKKRIMH FVGLNF
Length:516
Mass (Da):58,070
Last modified:May 1, 2000 - v2
Checksum:i2636215BD9CA344D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92746.2.
PIRiC88827.
T23827.
RefSeqiNP_001255535.1. NM_001268606.1.
UniGeneiCel.12595.

Genome annotation databases

EnsemblMetazoaiM7.2a; M7.2a; WBGene00002214.
GeneIDi178007.

Similar proteinsi

Entry informationi

Entry nameiQ21592_CAEEL
AccessioniPrimary (citable) accession number: Q21592
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: May 1, 2000
Last modified: August 30, 2017
This is version 139 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported