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Protein
Submitted name:

M7.2a

Gene

klc-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • establishment of meiotic spindle localization Source: WormBase
  • polar body extrusion after meiotic divisions Source: WormBase
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_304171. Kinesins.

Names & Taxonomyi

Protein namesi
Submitted name:
M7.2aImported
Gene namesi
Name:klc-1Imported
ORF Names:CELE_M7.2Imported, M7.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiM7.2a; CE23882; WBGene00002214; klc-1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ21592.
PRIDEiQ21592.

Expressioni

Gene expression databases

ExpressionAtlasiQ21592. baseline.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
meg-4Q9TZK83EBI-316831,EBI-314126

Protein-protein interaction databases

DIPiDIP-26939N.
IntActiQ21592. 3 interactions.
MINTiMINT-251335.
STRINGi6239.M7.2.

Structurei

3D structure databases

ProteinModelPortaliQ21592.
SMRiQ21592. Positions 195-458.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

RepeatUniRule annotation, TPR repeatUniRule annotation

Phylogenomic databases

eggNOGiCOG0457.
GeneTreeiENSGT00390000006393.
HOGENOMiHOG000261663.
PhylomeDBiQ21592.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR002151. Kinesin_light.
IPR015390. Rabaptin_Rab5-bd_dom.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR013105. TPR_2.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF09311. Rab5-bind. 1 hit.
PF00515. TPR_1. 1 hit.
PF07719. TPR_2. 1 hit.
[Graphical view]
PRINTSiPR00381. KINESINLIGHT.
SMARTiSM00028. TPR. 4 hits.
[Graphical view]
PROSITEiPS50005. TPR. 4 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q21592-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVISLGDDIT TVLKTVQQTL FALRDEHEAA TRILEANLIN SDSSEPSLPS
60 70 80 90 100
EKMGLIDESL GKVMDGGDEA SLLIMMDKLM QSYDVQLSKN HESIRLLRQE
110 120 130 140 150
NTWLLDELTT TQRKLQESER TVAHLEEERD HYKFQDSMNY LNSDFQHTTS
160 170 180 190 200
VDATPMMVDT LQELGFGPEE EDQNNNQADQ GCRSSSFSNP ISNDYQLPTR
210 220 230 240 250
LQTLQNLVIQ YMEQGRFEVA IPLCKQALED VVKVHGNVHL DVATMLNVLA
260 270 280 290 300
IVYRNQENFK DAAIYLEKAL SIRVQCCGEN HHSVAATLNN LAIAYGKRGK
310 320 330 340 350
YKESEPLCKR ALEIRKNLLG PNHPDVAKQL TNLGIVTQQL EKYEETENYF
360 370 380 390 400
KQALSIYNRA FPENHQNVIK TKNQLASVFL KQGKYQEAEE MYKNILSKVA
410 420 430 440 450
ITGNKPIWRI AEDREERQRN GIPKVDDESF NVNPTTVMDS NVMSTIKNLA
460 470 480 490 500
AVYRKQGKEE AAGTLEEALG AKKQINGGAD HTNSTASSVE TSSAVAINPA
510
QSGIKKRIMH FVGLNF
Length:516
Mass (Da):58,070
Last modified:May 1, 2000 - v2
Checksum:i2636215BD9CA344D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92746.2.
PIRiC88827.
T23827.
RefSeqiNP_001255535.1. NM_001268606.1.
UniGeneiCel.12595.

Genome annotation databases

EnsemblMetazoaiM7.2a; M7.2a; WBGene00002214.
GeneIDi178007.
KEGGicel:CELE_M7.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92746.2.
PIRiC88827.
T23827.
RefSeqiNP_001255535.1. NM_001268606.1.
UniGeneiCel.12595.

3D structure databases

ProteinModelPortaliQ21592.
SMRiQ21592. Positions 195-458.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-26939N.
IntActiQ21592. 3 interactions.
MINTiMINT-251335.
STRINGi6239.M7.2.

Proteomic databases

PaxDbiQ21592.
PRIDEiQ21592.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiM7.2a; M7.2a; WBGene00002214.
GeneIDi178007.
KEGGicel:CELE_M7.2.

Organism-specific databases

CTDi178007.
WormBaseiM7.2a; CE23882; WBGene00002214; klc-1.

Phylogenomic databases

eggNOGiCOG0457.
GeneTreeiENSGT00390000006393.
HOGENOMiHOG000261663.
PhylomeDBiQ21592.

Enzyme and pathway databases

ReactomeiREACT_304171. Kinesins.

Miscellaneous databases

NextBioi899338.

Gene expression databases

ExpressionAtlasiQ21592. baseline.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR002151. Kinesin_light.
IPR015390. Rabaptin_Rab5-bd_dom.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR013105. TPR_2.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF09311. Rab5-bind. 1 hit.
PF00515. TPR_1. 1 hit.
PF07719. TPR_2. 1 hit.
[Graphical view]
PRINTSiPR00381. KINESINLIGHT.
SMARTiSM00028. TPR. 4 hits.
[Graphical view]
PROSITEiPS50005. TPR. 4 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ21592_CAEEL
AccessioniPrimary (citable) accession number: Q21592
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: May 1, 2000
Last modified: May 27, 2015
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.