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Protein
Submitted name:

DeHydrogenases, Short chain

Gene

dhs-28

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • acyl-CoA metabolic process Source: UniProtKB
  • ascaroside biosynthetic process Source: UniProtKB
  • dauer entry Source: UniProtKB
  • negative regulation of lipid storage Source: UniProtKB
  • pheromone biosynthetic process Source: UniProtKB
  • positive regulation of developmental growth Source: UniProtKB
  • positive regulation of nematode larval development Source: UniProtKB
  • response to pheromone Source: UniProtKB
  • very long-chain fatty acid metabolic process Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
DeHydrogenases, Short chainImported
Gene namesi
Name:dhs-28Imported
ORF Names:CELE_M03A8.1Imported, M03A8.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiM03A8.1; CE04770; WBGene00000991; dhs-28.

Subcellular locationi

GO - Cellular componenti

  • peroxisome Source: WormBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiQ21481.
PaxDbiQ21481.
PRIDEiQ21481.

Expressioni

Gene expression databases

BgeeiWBGene00000991.

Interactioni

Protein-protein interaction databases

STRINGi6239.M03A8.1.

Structurei

3D structure databases

ProteinModelPortaliQ21481.
SMRiQ21481. Positions 3-295, 319-433.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini334 – 42895SCP2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1206. Eukaryota.
COG2030. LUCA.
GeneTreeiENSGT00530000062928.
InParanoidiQ21481.
OMAiHFRENGF.
OrthoDBiEOG091G02S9.
PhylomeDBiQ21481.

Family and domain databases

Gene3Di3.30.1050.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR003033. SCP2_sterol-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 3 hits.
PfamiPF00106. adh_short. 1 hit.
PF02036. SCP2. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF55718. SSF55718. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q21481-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLRFDGKVA IVTGAGGGLG KTYALELAKR GCKVVVNDLG GDRHGTSSSS
60 70 80 90 100
SMADKVVQEI KSAGGQAVAN YDSVEFGDKI VKTAIDNFGR IDIVINNAGI
110 120 130 140 150
LRDVSFLKMT ELDWDLIFKV HVKGAYAVTK AAWPYMRDQK YGRIVVTSSN
160 170 180 190 200
AGVHGNFGQA NYAAAKSALI GLSNSLAQEG AKYNILANTL VPTAGSRLTE
210 220 230 240 250
TVMPQNLVDA LKPDYVTPLV TYMVHDSFEE SGKVFEAGAG WYGTIQYYKS
260 270 280 290 300
KGKVISHASA DDIAKNWSTI TNMNGAEYIG TITEQSARLV SILEEHEASS
310 320 330 340 350
GSSSASSGAS SGGAFPSNIR SSALFQEMAD GVKADPTAVK TLKSIVLYII
360 370 380 390 400
TDGKNELGKF TLDFKSASPS VYLGDVKNGE KANATVTVAD SDFVDIAAGK
410 420 430
LNAQKAFMSG KLKVKGNVML LQKLQTVLEK AKKSKL
Length:436
Mass (Da):46,263
Last modified:November 1, 1996 - v1
Checksum:i2DBD94562A09BE55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CCD70982.1.
PIRiT16638.
RefSeqiNP_509146.1. NM_076745.5.
UniGeneiCel.9031.

Genome annotation databases

EnsemblMetazoaiM03A8.1; M03A8.1; WBGene00000991.
GeneIDi180950.
KEGGicel:CELE_M03A8.1.
UCSCiM03A8.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CCD70982.1.
PIRiT16638.
RefSeqiNP_509146.1. NM_076745.5.
UniGeneiCel.9031.

3D structure databases

ProteinModelPortaliQ21481.
SMRiQ21481. Positions 3-295, 319-433.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.M03A8.1.

Proteomic databases

EPDiQ21481.
PaxDbiQ21481.
PRIDEiQ21481.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiM03A8.1; M03A8.1; WBGene00000991.
GeneIDi180950.
KEGGicel:CELE_M03A8.1.
UCSCiM03A8.1. c. elegans.

Organism-specific databases

CTDi180950.
WormBaseiM03A8.1; CE04770; WBGene00000991; dhs-28.

Phylogenomic databases

eggNOGiKOG1206. Eukaryota.
COG2030. LUCA.
GeneTreeiENSGT00530000062928.
InParanoidiQ21481.
OMAiHFRENGF.
OrthoDBiEOG091G02S9.
PhylomeDBiQ21481.

Miscellaneous databases

PROiQ21481.

Gene expression databases

BgeeiWBGene00000991.

Family and domain databases

Gene3Di3.30.1050.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR003033. SCP2_sterol-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 3 hits.
PfamiPF00106. adh_short. 1 hit.
PF02036. SCP2. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF55718. SSF55718. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ21481_CAEEL
AccessioniPrimary (citable) accession number: Q21481
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.