Glycosyltransferase-like protein LARGE - Caenorhabditis elegans

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Reviewed, UniProtKB/Swiss-Prot Q21389 (LGE1_CAEEL)

Last modified June 16, 2009. Version 55. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein names

Recommended name:
Glycosyltransferase-like protein LARGE
EC=2.4.-.-

Gene names

Name:	lge-1
ORF Names:	K09C8.4

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	631 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Probable glycosyltransferase By similarity.
Subcellular location	Golgi apparatus membrane; Single-pass type II membrane protein By similarity.
Sequence similarities	Belongs to the glycosyltransferase 8 family.
Sequence caution	The sequence CAA91997.2 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Cellular component	Golgi apparatus Membrane
Domain	Signal-anchor Transmembrane
Molecular function	Glycosyltransferase Transferase
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	Golgi membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

631

Glycosyltransferase-like protein LARGE

PRO_0000226818

Regions

Topological domain

6

Cytoplasmic Potential

Transmembrane

21

Signal-anchor for type II membrane protein Potential

Topological domain

604

Lumenal Potential

Amino acid modifications

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Sequences

Sequence

Length

Mass (Da)

Tools

Q21389-1 [UniParc].

Last modified March 7, 2006. Version 3.
Checksum: F184CCC5C4959C90
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631

74,525

        10         20         30         40         50         60 
MQSNYSISYF LLILFTGTSS YFTIWNFVDH TRVGAFPEED YIRLAYIIGG NFMTRLMFMQ 

        70         80         90        100        110        120 
HFKSVLKYSD HFFRLHLITD ENHRSDIHEL MTSWNISNCE WFFHNLTEFE KRVAWIPNSH 

       130        140        150        160        170        180 
YSKYYGLSKL LIPEIIGNDI GKIMFMDVDI IFQTNIFDLW KQFRNFNNSQ VFGMVENLSD 

       190        200        210        220        230        240 
WYLNKDGKKS VWPALGRGFN TGIIMFDLDK LRKNGWASKW RVVANKYLRI HGKTAMSDQD 

       250        260        270        280        290        300 
IFNAYIHDYP TEIIQIPCAY NYQLGALTKS KELCPETPLA LHFNSQNKTV GKNYAFFDKI 

       310        320        330        340        350        360 
RKAFDEMDGS DLKRRRRSFK GNNQKDICHE YLPLDNFRII PNAIGRMTKP AELCMVTQFS 

       370        380        390        400        410        420 
KDRLNHFLES ANAWRHPIST AVYGKDKDLL DIAKAVTELN RTDITIHLVF EEPTESWMLD 

       430        440        450        460        470        480 
SLYPINFLRN VAIEHANCKY ILMTDVDFVV LGDYGTIIDQ TGNLKQKEVL VIPALEMTYP 

       490        500        510        520        530        540 
QLRLNLSNFL SRKDLVIEHL LNKTIQTFRE TIWPSSHVPT NISKWIKSNR TYMVNYEKNY 

       550        560        570        580        590        600 
EPYFVIKKEE CPFYDQRFGG FGWNKVTHVM QLKMMNYKFL VSPTSFMIHQ NHNASKSLKR 

       610        620        630 
WRRDPHYQKC LHTLKNKFMK KTASRLGIKL R

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

Cross-references

Sequence databases
	Z68006 Genomic DNA. Translation: CAA91997.2. Sequence problems.
PIR	T23541.
UniGene	Cel.695
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT49. Glycosyltransferase Family 49. GT8. Glycosyltransferase Family 8.
Genome annotation databases
Ensembl	K09C8.4. Caenorhabditis elegans. [Contig view]
Organism-specific databases
WormBase	WBGene00010716. lge-1.
WormPep	K09C8.4. CE36552. [WorfDB]
Family and domain databases
InterPro	IPR002495. Glyco_trans_8. [Graphical view]
Pfam	PF01501. Glyco_transf_8. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LGE1_CAEEL

Accession

Primary (citable) accession number: Q21389

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 7, 2006
Last sequence update:	March 7, 2006
Last modified:	June 16, 2009
This is version 55 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormPep

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents