Probable cation-transporting ATPase K07E3.7

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Q21286 (YBF7_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 101. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Probable cation-transporting ATPase K07E3.7
EC=3.6.3.-

Gene names

ORF Names:

K07E3.7/K07E3.6

Organism

Caenorhabditis elegans [Reference proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	1203 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + H₂O = ADP + phosphate.
Subcellular location	Membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. [View classification]

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Alternative splicing
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Magnesium Metal-binding Nucleotide-binding
Molecular function	Hydrolase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cation-transporting ATPase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform b (identifier: Q21286-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Note: No experimental confirmation available.

Isoform a (identifier: Q21286-2) The sequence of this isoform differs from the canonical sequence as follows: 1-29: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 1203

1203

Probable cation-transporting ATPase K07E3.7

PRO_0000046356

Regions

Topological domain

1 – 68

Cytoplasmic Potential

Transmembrane

69 – 89

Helical; Potential

Topological domain

90 – 209

120

Extracellular Potential

Transmembrane

210 – 230

Helical; Potential

Topological domain

231 – 242

Cytoplasmic Potential

Transmembrane

243 – 263

Helical; Potential

Topological domain

264 – 297

Extracellular Potential

Transmembrane

298 – 318

Helical; Potential

Topological domain

319 – 414

Cytoplasmic Potential

Transmembrane

415 – 435

Helical; Potential

Topological domain

436 – 451

Extracellular Potential

Transmembrane

452 – 472

Helical; Potential

Topological domain

473 – 935

463

Cytoplasmic Potential

Transmembrane

936 – 956

Helical; Potential

Topological domain

957 – 962

Extracellular Potential

Transmembrane

963 – 983

Helical; Potential

Topological domain

984 – 1007

Cytoplasmic Potential

Transmembrane

1008 – 1028

Helical; Potential

Topological domain

1029 – 1046

Extracellular Potential

Transmembrane

1047 – 1067

Helical; Potential

Topological domain

1068 – 1085

Cytoplasmic Potential

Transmembrane

1086 – 1106

Helical; Potential

Topological domain

1107 – 1120

Extracellular Potential

Transmembrane

1121 – 1141

Helical; Potential

Topological domain

1142 – 1203

Cytoplasmic Potential

Sites

Active site

503

4-aspartylphosphate intermediate By similarity

Metal binding

883

Magnesium By similarity

Metal binding

887

Magnesium By similarity

Natural variations

Alternative sequence

1 – 29

Missing in isoform a.

VSP_012458

Sequences

Sequence		Length	Mass (Da)
Isoform b [UniParc]. Last modified January 4, 2005. Version 4. Checksum: 474DAF607FF8BFA0 Show »	FASTA	1,203	134,704
10 20 30 40 50 60 MNTSEREPLL DTTTRNRVYD TTDNPSTKIM KREKDNPKAK TTSFNQGKLN IGEETCDLYA 70 80 90 100 110 120 YKETIGRQIL FWLLTIVTLG FYQLLAYWVK SLFVKVRFQP TSHDECEYVM VEDIHGTQTI 130 140 150 160 170 180 KEVFKAESDV GLARPTRSGK QEKVKVMRFF TYRKIKYIWY EKDQEWLNPA DMDSAAPFNI 190 200 210 220 230 240 YQKLTLDVIG LKEQDVIASR KIYNMNALAL ALTPILVILF KEVLGPFYLF QCFSVALWYS 250 260 270 280 290 300 DNYAYYASVI VIITVGSAAV AVYQMRAQEK RIRNMVGDTI SVIVRRDGHD ITIDASEIVP 310 320 330 340 350 360 MDILILPSNT FILPCDCLLM NGTVIVNEAM LTGESVPVTK ASLKEADECG PEIRLSSEHN 370 380 390 400 410 420 RHTLFSGTTV LQTRNYKGQP VMARVIRTGF STLKGQLVRS IMYPKPQEKE ALKDVMVFIL 430 440 450 460 470 480 VLGFIALIGF IYTVIEMVSR GESLKHIIIR SLDIITIVVP PALPAAMSVG IINANSRLKK 490 500 510 520 530 540 KKIFCTSPTT VNVCGLINVA CFDKTGTLTE DGLDFNCLKA IRKNEDGKPE FTSEFEELDP 550 560 570 580 590 600 VKLSAENANL NIVVAAASCH SLTRIDGTLH GDPLELILVE KSKWIIEEAV NSDEETQDFD 610 620 630 640 650 660 TVQPTVLRPP PEQATYHPEN NEYSVIKQHP FNSALQRMSV IISTPSEHSA HDMMVFTKGS 670 680 690 700 710 720 PEMIASLCIP DTIPEDYMEV VDEYAQRGFR LIAVASKAVH LNFAKALKTP RDIMESELEF 730 740 750 760 770 780 LGLIVMENRL KDVTLSVINE LSVANIRCVM VTGDNLLTAM SVARECGIIR PTKKAFLITH 790 800 810 820 830 840 SKTEKDPLGR TKLFIKESVS SSENDIDTDS EVRAFDRKAV LRTATYQMAI AGPTYSVITH 850 860 870 880 890 900 EYPELVDRIT AMCDVYARMA PDQKAQLIGA LQEIGAKVSM CGDGANDCAA LKAAHAGISL 910 920 930 940 950 960 SQAEASIAAP FTSNVPDIRC VPTVIKEGRC ALVTSYAVSK YMAAYSLNEF LSVMLLYNDG 970 980 990 1000 1010 1020 TNISDGQFLY IDLVLITLVA LFLGNTEASR KLSGIPPPRR LATSAFYFSV FGQMFFNIIT 1030 1040 1050 1060 1070 1080 QTTGYLLVRG QSWYVPNPEE LDNTTTMIGT TVFFTSCCMY LGYAFVYSKG HPYRRSVFTN 1090 1100 1110 1120 1130 1140 WLLCGIIFVI GAINMVMIFT NMGFLMNLMG FVYVPSTSMR FILLAISLAG VFLSLLYEHF 1150 1160 1170 1180 1190 1200 FVEKVVAIHF ESYLRQRRLR NGDPSLSAYE KILAAIGSSP RWFEDEINLS KSIDRKETIE SKC « Hide
Isoform a [UniParc]. Checksum: 136A66790C63D166 Show »	FASTA	1,174	131,352
10 20 30 40 50 60 MKREKDNPKA KTTSFNQGKL NIGEETCDLY AYKETIGRQI LFWLLTIVTL GFYQLLAYWV 70 80 90 100 110 120 KSLFVKVRFQ PTSHDECEYV MVEDIHGTQT IKEVFKAESD VGLARPTRSG KQEKVKVMRF 130 140 150 160 170 180 FTYRKIKYIW YEKDQEWLNP ADMDSAAPFN IYQKLTLDVI GLKEQDVIAS RKIYNMNALA 190 200 210 220 230 240 LALTPILVIL FKEVLGPFYL FQCFSVALWY SDNYAYYASV IVIITVGSAA VAVYQMRAQE 250 260 270 280 290 300 KRIRNMVGDT ISVIVRRDGH DITIDASEIV PMDILILPSN TFILPCDCLL MNGTVIVNEA 310 320 330 340 350 360 MLTGESVPVT KASLKEADEC GPEIRLSSEH NRHTLFSGTT VLQTRNYKGQ PVMARVIRTG 370 380 390 400 410 420 FSTLKGQLVR SIMYPKPQEK EALKDVMVFI LVLGFIALIG FIYTVIEMVS RGESLKHIII 430 440 450 460 470 480 RSLDIITIVV PPALPAAMSV GIINANSRLK KKKIFCTSPT TVNVCGLINV ACFDKTGTLT 490 500 510 520 530 540 EDGLDFNCLK AIRKNEDGKP EFTSEFEELD PVKLSAENAN LNIVVAAASC HSLTRIDGTL 550 560 570 580 590 600 HGDPLELILV EKSKWIIEEA VNSDEETQDF DTVQPTVLRP PPEQATYHPE NNEYSVIKQH 610 620 630 640 650 660 PFNSALQRMS VIISTPSEHS AHDMMVFTKG SPEMIASLCI PDTIPEDYME VVDEYAQRGF 670 680 690 700 710 720 RLIAVASKAV HLNFAKALKT PRDIMESELE FLGLIVMENR LKDVTLSVIN ELSVANIRCV 730 740 750 760 770 780 MVTGDNLLTA MSVARECGII RPTKKAFLIT HSKTEKDPLG RTKLFIKESV SSSENDIDTD 790 800 810 820 830 840 SEVRAFDRKA VLRTATYQMA IAGPTYSVIT HEYPELVDRI TAMCDVYARM APDQKAQLIG 850 860 870 880 890 900 ALQEIGAKVS MCGDGANDCA ALKAAHAGIS LSQAEASIAA PFTSNVPDIR CVPTVIKEGR 910 920 930 940 950 960 CALVTSYAVS KYMAAYSLNE FLSVMLLYND GTNISDGQFL YIDLVLITLV ALFLGNTEAS 970 980 990 1000 1010 1020 RKLSGIPPPR RLATSAFYFS VFGQMFFNII TQTTGYLLVR GQSWYVPNPE ELDNTTTMIG 1030 1040 1050 1060 1070 1080 TTVFFTSCCM YLGYAFVYSK GHPYRRSVFT NWLLCGIIFV IGAINMVMIF TNMGFLMNLM 1090 1100 1110 1120 1130 1140 GFVYVPSTSM RFILLAISLA GVFLSLLYEH FFVEKVVAIH FESYLRQRRL RNGDPSLSAY 1150 1160 1170 EKILAAIGSS PRWFEDEINL SKSIDRKETI ESKC « Hide

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING. Strain: Bristol N2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FO080274 Genomic DNA. Translation: CCD62517.1. FO080274 Genomic DNA. Translation: CCD62518.1.
PIR	A89583.
RefSeq	NP_001024767.1. NM_001029596.2. NP_001024768.1. NM_001029597.1.
UniGene	Cel.718.
3D structure databases
ProteinModelPortal	Q21286.
SMR	Q21286. Positions 218-1008.
ModBase	Search...
Proteomic databases
PaxDb	Q21286.
PRIDE	Q21286.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	K07E3.7b; K07E3.7b; K07E3.7.
GeneID	181067.
KEGG	cel:CELE_K07E3.7.
Organism-specific databases
CTD	181067.
WormBase	K07E3.7a; CE37253; WBGene00019493; catp-5. K07E3.7b; CE37254; WBGene00019493; catp-5.
Phylogenomic databases
eggNOG	COG0474.
GeneTree	ENSGT00530000063001.
HOGENOM	HOG000171813.
InParanoid	Q21286.
KO	K14951.
OMA	MSVAREC.
Family and domain databases
Gene3D	2.70.150.10. 1 hit. 3.40.1110.10. 2 hits. 3.40.50.1000. 2 hits.
InterPro	IPR006544. ATPase_P-typ_Cation_typ_V. IPR023299. ATPase_P-typ_cyto_domN. IPR018303. ATPase_P-typ_P_site. IPR008250. ATPase_P-typ_transduc_dom_A. IPR001757. Cation_transp_P_typ_ATPase. IPR023214. HAD-like_dom. [Graphical view]
PANTHER	PTHR24093. PTHR24093. 1 hit.
Pfam	PF00122. E1-E2_ATPase. 1 hit. PF12409. P5-ATPase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01494. ATPase_P-type. 3 hits. TIGR01657. P-ATPase-V. 1 hit.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	912258.

Entry information

Entry name

YBF7_CAEEL

Accession

Primary (citable) accession number: Q21286
Secondary accession number(s): Q10461, Q65ZI7, Q65ZI8

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 4, 2005
Last modified:	May 1, 2013
This is version 101 of the entry and version 4 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Caenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Alternative products

Sequence annotation (Features)

Molecule processing

Regions

Sites

Natural variations

Sequences

References

Cross-references

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Other

Entry information

Relevant documents