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Protein

Pre-mRNA-splicing factor SLU7

Gene

K07C5.6

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri113 – 130CCHC-typePROSITE-ProRule annotationAdd BLAST18

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

mRNA processing, mRNA splicing

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-CEL-109688. Cleavage of Growing Transcript in the Termination Region.
R-CEL-159236. Transport of Mature mRNA derived from an Intron-Containing Transcript.
R-CEL-72187. mRNA 3'-end processing.

Names & Taxonomyi

Protein namesi
Recommended name:
Pre-mRNA-splicing factor SLU7
Gene namesi
ORF Names:K07C5.6
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiK07C5.6; CE06116; WBGene00010629.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002892011 – 647Pre-mRNA-splicing factor SLU7Add BLAST647

Proteomic databases

EPDiQ21278.
PaxDbiQ21278.
PeptideAtlasiQ21278.
PRIDEiQ21278.

PTM databases

iPTMnetiQ21278.

Expressioni

Gene expression databases

BgeeiWBGene00010629.

Interactioni

Protein-protein interaction databases

BioGridi44473. 1 interactor.
STRINGi6239.K07C5.6.1.

Structurei

3D structure databases

ProteinModelPortaliQ21278.
SMRiQ21278.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SLU7 family.Curated
Contains 1 CCHC-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri113 – 130CCHC-typePROSITE-ProRule annotationAdd BLAST18

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG2560. Eukaryota.
ENOG410XPPP. LUCA.
GeneTreeiENSGT00390000002292.
HOGENOMiHOG000194391.
InParanoidiQ21278.
KOiK12819.
OMAiVIEDYEH.
OrthoDBiEOG091G05PK.
PhylomeDBiQ21278.

Family and domain databases

Gene3Di4.10.60.10. 1 hit.
InterProiIPR021715. Slu7.
IPR001878. Znf_CCHC.
[Graphical view]
PfamiPF11708. Slu7. 1 hit.
PF00098. zf-CCHC. 1 hit.
[Graphical view]
SUPFAMiSSF57756. SSF57756. 1 hit.
PROSITEiPS50158. ZF_CCHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q21278-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASYKQNLPP SALIKQQVNV ADKKSKAEVQ RDRQLEEDRK AGTAPAMVDV
60 70 80 90 100
QTGRDINPHI PMFISQNPWY VPSEGPTLKH QRPHEEREKK MTQIHEWYQK
110 120 130 140 150
GTTGKSATKF RKGACENCGA MGHQKRDCFD RPRKSNAKET NDNIAEDDYV
160 170 180 190 200
QPNLTLGFDA KRDRWNGYDP STHKQVIEDY EHLEEARKVV REHEMKEGEV
210 220 230 240 250
EPATTEDGAP KDEDMYAEDA DMAGVSVDMD SRTRITVRNL RIREDTAKYL
260 270 280 290 300
YNLAENSPYY DPKSRSMREN PFAGVAGKEL EAARFSGDNF VRYSGEVTAA
310 320 330 340 350
NEAQVFAWQA TRGGVYAHSI AEPTKLEALK KEYEKEKSTL KNETQKELLD
360 370 380 390 400
KYGGGEHMER PADELLLAQT ESYIEYNRKG KVIKGKEKVA ISSRFKEDIY
410 420 430 440 450
PQNHTSVFGS FWREGRWGYK CCHQFVKNSY CTGKQGIEAE TSAAKGTTTS
460 470 480 490 500
NEEIFKVPKL VEKTEVKEEK EKEDSIKDEV AEENSDNDND EEKEKVSEKS
510 520 530 540 550
ISPSPPSDDE EKEKEREKER LIEKERRERD QRRRDKKREK RERKKAKLGK
560 570 580 590 600
RKRRHRDSDD ESDPSSGSGS ESDSDEEMRK AMKKAKREKA EGMKAAREGD
610 620 630 640
RGRKYNTDYS NTAPNEKEME AYRVTSVHSA DPMAAYMNSK FEKKHTK
Length:647
Mass (Da):74,461
Last modified:November 1, 1996 - v1
Checksum:iC506C0E13ACAF1CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71181 Genomic DNA. Translation: CAA94899.1.
PIRiT23407.
RefSeqiNP_505661.1. NM_073260.4.
UniGeneiCel.7080.

Genome annotation databases

EnsemblMetazoaiK07C5.6; K07C5.6; WBGene00010629.
GeneIDi179443.
KEGGicel:CELE_K07C5.6.
UCSCiK07C5.6.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71181 Genomic DNA. Translation: CAA94899.1.
PIRiT23407.
RefSeqiNP_505661.1. NM_073260.4.
UniGeneiCel.7080.

3D structure databases

ProteinModelPortaliQ21278.
SMRiQ21278.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi44473. 1 interactor.
STRINGi6239.K07C5.6.1.

PTM databases

iPTMnetiQ21278.

Proteomic databases

EPDiQ21278.
PaxDbiQ21278.
PeptideAtlasiQ21278.
PRIDEiQ21278.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiK07C5.6; K07C5.6; WBGene00010629.
GeneIDi179443.
KEGGicel:CELE_K07C5.6.
UCSCiK07C5.6.1. c. elegans.

Organism-specific databases

CTDi179443.
WormBaseiK07C5.6; CE06116; WBGene00010629.

Phylogenomic databases

eggNOGiKOG2560. Eukaryota.
ENOG410XPPP. LUCA.
GeneTreeiENSGT00390000002292.
HOGENOMiHOG000194391.
InParanoidiQ21278.
KOiK12819.
OMAiVIEDYEH.
OrthoDBiEOG091G05PK.
PhylomeDBiQ21278.

Enzyme and pathway databases

ReactomeiR-CEL-109688. Cleavage of Growing Transcript in the Termination Region.
R-CEL-159236. Transport of Mature mRNA derived from an Intron-Containing Transcript.
R-CEL-72187. mRNA 3'-end processing.

Miscellaneous databases

PROiQ21278.

Gene expression databases

BgeeiWBGene00010629.

Family and domain databases

Gene3Di4.10.60.10. 1 hit.
InterProiIPR021715. Slu7.
IPR001878. Znf_CCHC.
[Graphical view]
PfamiPF11708. Slu7. 1 hit.
PF00098. zf-CCHC. 1 hit.
[Graphical view]
SUPFAMiSSF57756. SSF57756. 1 hit.
PROSITEiPS50158. ZF_CCHC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSLU7_CAEEL
AccessioniPrimary (citable) accession number: Q21278
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.