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Protein
Submitted name:

AMPHiphysin homolog

Gene

amph-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • lipid tube assembly involved in organelle fission Source: WormBase
  • nucleus localization Source: WormBase
  • nucleus organization Source: WormBase

Enzyme and pathway databases

ReactomeiR-CEL-8856828. Clathrin-mediated endocytosis.
SignaLinkiQ21004.

Names & Taxonomyi

Protein namesi
Submitted name:
AMPHiphysin homologImported
Gene namesi
Name:amph-1Imported
ORF Names:CELE_F58G6.1Imported, F58G6.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiF58G6.1; CE03428; WBGene00010272; amph-1.

Subcellular locationi

GO - Cellular componenti

  • nuclear envelope Source: WormBase
  • perinuclear region of cytoplasm Source: WormBase
  • recycling endosome Source: WormBase

PTM / Processingi

Proteomic databases

EPDiQ21004.
PaxDbiQ21004.
PeptideAtlasiQ21004.

Expressioni

Gene expression databases

BgeeiWBGene00010272.

Interactioni

Protein-protein interaction databases

IntActiQ21004. 2 interactors.
STRINGi6239.F58G6.1.2.

Structurei

3D structure databases

ProteinModelPortaliQ21004.
SMRiQ21004.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 237BARInterPro annotationAdd BLAST218
Domaini398 – 461SH3InterPro annotationAdd BLAST64

Keywords - Domaini

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3771. Eukaryota.
ENOG410ZBW1. LUCA.
GeneTreeiENSGT00390000017588.
HOGENOMiHOG000021793.
InParanoidiQ21004.
KOiK12562.
OMAiECYSIFE.
OrthoDBiEOG091G0JRY.
PhylomeDBiQ21004.

Family and domain databases

InterProiView protein in InterPro
IPR027267. AH/BAR-dom.
IPR003005. Amphiphysin.
IPR004148. BAR_dom.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF03114. BAR. 1 hit.
PF14604. SH3_9. 1 hit.
PRINTSiPR01251. AMPHIPHYSIN.
SMARTiView protein in SMART
SM00721. BAR. 1 hit.
SM00326. SH3. 1 hit.
SUPFAMiSSF103657. SSF103657. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiView protein in PROSITE
PS51021. BAR. 1 hit.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q21004-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADLFNKHLK KATNRTKEKL LEGIGKAKAT QDEVFDQHAA NLNKQSKSCE
60 70 80 90 100
KLHKDVKNYS SALRTLLSAE KQLRDTIRDA YEPEWPDREH LTAIFDNLDI
110 120 130 140 150
QTNELEKTVC DDLPQTVTQY VNQFPDLKKK IEKRGRKLVD YDSAKNSFNS
160 170 180 190 200
VKASSKKDND PKLAKATMEL QAAEQMYTEM NNELLEILPA VFDSRITFFV
210 220 230 240 250
DTLQTLFNAN SVYQTDASKF HKQIVMQLDK LGESMDYLRV ARPEARALTP
260 270 280 290 300
IDTTSLASSD APATPDQNKS DNSSLRQTPS PSVLPSPVPA PMAKPRESVV
310 320 330 340 350
SMANSTNPFD DDDAEHDKEA TPTDVEEKFE AKVYPKLNAQ QTAAAEQAIA
360 370 380 390 400
AAKREKKEAS NPFDDEDDES TEVEEAPKKK DPEPTPKPLD GITNEKRKTL
410 420 430 440 450
YFVTSTHNYK AVDTDELSFE QGVQIKVIEA NEDDQLDDGW RLGELEDGKR
460
GVFPENFTKK V
Length:461
Mass (Da):51,911
Last modified:November 1, 1996 - v1
Checksum:i771C89E21EF7BEC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92465.1.
PIRiT22946.
RefSeqiNP_501711.1. NM_069310.3.
UniGeneiCel.8039.

Genome annotation databases

EnsemblMetazoaiF58G6.1.1; F58G6.1.1; WBGene00010272.
F58G6.1.2; F58G6.1.2; WBGene00010272.
GeneIDi177797.
KEGGicel:CELE_F58G6.1.
UCSCiF58G6.1.1. c. elegans.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ21004_CAEEL
AccessioniPrimary (citable) accession number: Q21004
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 7, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported