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Protein

Chemotaxis response regulator protein-glutamate methylesterase 1

Gene

cheB1

Organism
Rhodopseudomonas palustris (strain BisB18)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR.UniRule annotation

Catalytic activityi

Protein L-glutamate O5-methyl ester + H2O = protein L-glutamate + methanol.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei205UniRule annotation1
Active sitei233UniRule annotation1
Active sitei329UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processChemotaxis

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis response regulator protein-glutamate methylesterase 1UniRule annotation (EC:3.1.1.61UniRule annotation)
Gene namesi
Name:cheB1UniRule annotation
Ordered Locus Names:RPC_4244
OrganismiRhodopseudomonas palustris (strain BisB18)
Taxonomic identifieri316056 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001948 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002643061 – 389Chemotaxis response regulator protein-glutamate methylesterase 1Add BLAST389

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei714-aspartylphosphateUniRule annotation1

Post-translational modificationi

Phosphorylated by CheA. Phosphorylation suppresses the inhibitory activity of the N-terminal domain.UniRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi316056.RPC_4244.

Structurei

3D structure databases

ProteinModelPortaliQ20YL8.
SMRiQ20YL8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 138Response regulatoryPROSITE-ProRule annotationAdd BLAST119
Domaini193 – 387CheB-type methylesteraseUniRule annotationAdd BLAST195

Domaini

The N-terminal regulatory domain inhibits the activity of the C-terminal effector domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMP. Bacteria.
COG2201. LUCA.
HOGENOMiHOG000151424.
KOiK03412.
OMAiVITIDYE.
OrthoDBiPOG091H045J.

Family and domain databases

CDDicd16432. CheB_Rec. 1 hit.
cd00156. REC. 1 hit.
Gene3Di3.40.50.180. 1 hit.
HAMAPiMF_00099. CheB_methylest. 1 hit.
InterProiView protein in InterPro
IPR035909. CheB_C.
IPR011006. CheY-like_superfamily.
IPR008248. Sig_transdc_resp-reg_CheB.
IPR000673. Sig_transdc_resp-reg_Me-estase.
IPR001789. Sig_transdc_resp-reg_receiver.
PfamiView protein in Pfam
PF01339. CheB_methylest. 1 hit.
PF00072. Response_reg. 1 hit.
PIRSFiPIRSF000876. RR_chemtxs_CheB. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF52738. SSF52738. 1 hit.
PROSITEiView protein in PROSITE
PS50122. CHEB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q20YL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIAVASASI PEPVRYEPLR VMVVDDSVVI RGLISRWIEA EPDMVVAASL
60 70 80 90 100
RTGLDAVNQV ERVKPDVALL DIEMPELDGI SALPQLLAKQ RNLIIIMAST
110 120 130 140 150
LTRRNAEISF KALSLGAADY IPKPESTREA SAAEIFRHDL LQKVRSLGAR
160 170 180 190 200
VRRKVQTGPG AVAAPAIVRA REPAPVPAAG HAPAVPLLRR ALSLTAPRVL
210 220 230 240 250
LIGSSTGGPQ ALMTLVADIG AVIDRFPVLI TQHMPPTFTT ILAEHLARAS
260 270 280 290 300
RRPAHEGIDG EIIKPGQIYL APGGKHMRVA RQGGNTVIAL DDGPAVNFCK
310 320 330 340 350
PAVDPLFISA IEVWQSAIMA VVLTGMGSDG MRGGKDVVAA GGSVIAQDEA
360 370 380
SSVVWGMPGA AANAGICAAI LPLNQIGQKL VRVFAGDRS
Length:389
Mass (Da):40,920
Last modified:April 18, 2006 - v1
Checksum:iA5EF7884284DD7D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000301 Genomic DNA. Translation: ABD89768.1.
RefSeqiWP_011474649.1. NC_007925.1.

Genome annotation databases

EnsemblBacteriaiABD89768; ABD89768; RPC_4244.
KEGGirpc:RPC_4244.

Similar proteinsi

Entry informationi

Entry nameiCHEB1_RHOPB
AccessioniPrimary (citable) accession number: Q20YL8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: April 18, 2006
Last modified: November 22, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome