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Q20WX2 (Q20WX2_RHOPB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607

EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:RPC_4842
OrganismRhodopseudomonas palustris (strain BisB18) [Complete proteome] [HAMAP]
Taxonomic identifier316056 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2401Iron By similarity HAMAP MF_00323
Metal binding3211Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
Q20WX2 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: F711EC441A74C329

FASTA37041,627
        10         20         30         40         50         60 
MSKARFRRML PYLDNIMPTR EANRLMTVIV PIHGPEAVAD QAPERVGVLL VNLGTPDSAD 

        70         80         90        100        110        120 
TKGVRDYLRE FLSDPRVIEN QGIVWKLALN GLILRTRPAR KARDYQKIWN NEANESPLKT 

       130        140        150        160        170        180 
ITRAQADKLA ATLTAHDHIV VDWAMRYGNP SMRSRIDALV AQGCNRLLVV PLYPQYSAAT 

       190        200        210        220        230        240 
SATVCDQAFR VLSEMRAQPT LRVTPPYYRD AAYIDALANS ISSHLATLPF EPERIVASFH 

       250        260        270        280        290        300 
GMPQAYINKG DPYQSHCIAT VDALRERMGL DEKRLMLTFQ SRFGFDQWLQ PYTDKTIEQL 

       310        320        330        340        350        360 
GKDGVRRLAV VMPGFASDCL ETLEEIAQEN AEIFMHNGGE KFAAVPCLND SDDGIAVIRQ 

       370 
LVLRELEGWL 

« Hide

References

[1]"Complete sequence of Rhodopseudomonas palustris BisB18."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Pelletier D.A., Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BisB18.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000301 Genomic DNA. Translation: ABD90364.1.
RefSeqYP_534683.1. NC_007925.1.

3D structure databases

ProteinModelPortalQ20WX2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ20WX2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3973546.
GenomeReviewsGene locus RPC_4842 in contig CP000301_GR.
KEGGrpc:RPC_4842.
PATRIC23274590. VBIRhoPal29154_4958.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMATIEEIGM.
PhylomeDBQ20WX2.
ProtClustDBPRK00035.

Enzyme and pathway databases

BioCycRPAL316056:RPC_4842-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ20WX2_RHOPB
AccessionPrimary (citable) accession number: Q20WX2
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)