Q20WM3 (Q20WM3_RHOPB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 2 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 2 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 2 HAMAP MF_01401

Gene names

Name:	msrA2 HAMAP MF_01401
Ordered Locus Names:	RPC_4941

Organism

Rhodopseudomonas palustris (strain BisB18) [Complete proteome] [HAMAP]

Taxonomic identifier

316056 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Domain	Signal EMBL ABD90463.1
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL ABD90463.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential EMBL ABD90463.1
	Chain	25 – 218	194	Potential EMBL ABD90463.1		PRO_5000114182
Sites
	Active site	54	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q20WM3 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 796D2E9313BD4823	FASTA	218	23,106
	10 20 30 40 50 60 MFFMRKTTAL PSAAEALPGR ATALPTASTH FVNGHRLQPP YPAGLQQAVF GLGCFWGAER 70 80 90 100 110 120 KFWALGDGVY VTAVGYAGGH TPNPTYEEVC SGRTGHTEAV LVVFDPARLS FEALLKVFWE 130 140 150 160 170 180 SHNPTQGMRQ GNDVGTQYRS AIYTFGDAQD KAAESSKAAY GRALAAKGLG AITTEIAPAD 190 200 210 IFYFAEDYHQ QYLAKNPAGY CGLGGTGVSC PIGAGVNA

References

[1]

"Complete sequence of Rhodopseudomonas palustris BisB18." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Pelletier D.A., Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BisB18.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000301 Genomic DNA. Translation: ABD90463.1.
RefSeq	YP_534782.1. NC_007925.1.
3D structure databases
ProteinModelPortal	Q20WM3.
SMR	Q20WM3. Positions 12-211.
ModBase	Search...
Protein-protein interaction databases
STRING	Q20WM3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3973858.
GenomeReviews	Gene locus RPC_4941 in contig CP000301_GR.
KEGG	rpc:RPC_4941.
PATRIC	23274796. VBIRhoPal29154_5060.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HBG748152.
OMA	SAIYCTT.
PhylomeDB	Q20WM3.
ProtClustDB	PRK00058.
Enzyme and pathway databases
BioCyc	RPAL316056:RPC_4941-MONOMER.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q20WM3_RHOPB

Accession

Primary (citable) accession number: Q20WM3

Entry history

Integrated into UniProtKB/TrEMBL:	April 18, 2006
Last sequence update:	April 18, 2006
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)