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Reviewed, UniProtKB/Swiss-Prot Q20848 (P5CR_CAEEL)

Last modified November 25, 2008. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Putative pyrroline-5-carboxylate reductase
      Short name=P5C reductase
      Short name=P5CR
    EC=1.5.1.2
Gene names
ORF Names: F55G1.9
OrganismCaenorhabditis elegans [Complete proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length299 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Catalytic activity

L-proline + NAD(P)(+) = 1-pyrroline-5-carboxylate + NAD(P)H.

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.

Sequence similarities

Belongs to the pyrroline-5-carboxylate reductase family.

Ontologies

Keywords

   Biological processAmino-acid biosynthesis
Proline biosynthesis
   LigandNADP
   Molecular functionOxidoreductase
   Technical termComplete proteome

Gene Ontology (GO)

   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

proline biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionbinding

Inferred from electronic annotation. Source: InterPro

pyrroline-5-carboxylate reductase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 299299Putative pyrroline-5-carboxylate reductase
PRO_0000187321

Sequences

Sequence LengthMass (Da)Tools
Q20848-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 75D2D6D32E0A5670

FASTA29932,057
        10         20         30         40         50         60 
MTIDTELTNG SSESVPFVFI GGGNMAAAII KGCQNKGFTP KSNIVIGVQT EKSAEKWRQL 

        70         80         90        100        110        120 
GYKNVFTNTL EMLERYSTAI YVICVKPQVF EEVVSSWPVN SRPEFIISVM AGVPLKVLNA 

       130        140        150        160        170        180 
KLPFVSGNTT IVRLMPNVAS SIGAGASTMC YEKNEKIMNQ DSHIELAREF AECVGTVELI 

       190        200        210        220        230        240 
PERCFNPAMA IGGSSPAWTF MYIESLADGA VAQGLGRAEA KRLAAQAVLG AAQMVLNSNS 

       250        260        270        280        290 
GFDIETQHFG SLKDMVCSPG GTTIEGVRAL EKNGFRYAVM EAVVAASTKA DEMAKSLAK 

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References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.

Cross-references

Sequence databases

U58750 Genomic DNA. Translation: AAB00645.1.
PIRT29226.
RefSeqNP_501199.1.
UniGeneCel.12859

3D structure databases

ModBaseSearch...

Genome annotation databases

EnsemblF55G1.9. Caenorhabditis elegans. [Contig view]
GeneID177519.
KEGGcel:F55G1.9.
NMPDRfig|6239.3.peg.13938.

Organism-specific databases

WormBaseWBGene00018904. F55G1.9.
WormPepF55G1.9. CE07286. [WorfDB]

Gene expression databases

ArrayExpressQ20848.

Family and domain databases

InterProIPR004455. NADP_OxRdtase_F420.
IPR000304. P5CR.
[Graphical view]
PANTHERPTHR11645. P5CR. 1 hit.
PfamPF03807. F420_oxidored. 1 hit.
[Graphical view]
PIRSFPIRSF000193. Pyrrol-5-carb_rd. 1 hit.
TIGRFAMsTIGR00112. proC. 1 hit.
PROSITEPS00521. P5CR. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio897180.

Entry information

Entry nameP5CR_CAEEL
AccessionPrimary (citable) accession number: Q20848
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: November 25, 2008
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectCaenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormPep

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents