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Protein

Putative calcium-binding mitochondrial carrier F55A11.4

Gene

F55A11.4

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Calcium-dependent mitochondrial solute carrier.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi86 – 971Add BLAST12
Calcium bindingi153 – 1642Add BLAST12

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative calcium-binding mitochondrial carrier F55A11.4
Gene namesi
ORF Names:F55A11.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei252 – 269Helical; Name=1Sequence analysisAdd BLAST18
Transmembranei307 – 326Helical; Name=2Sequence analysisAdd BLAST20
Transmembranei352 – 365Helical; Name=3Sequence analysisAdd BLAST14
Transmembranei403 – 422Helical; Name=4Sequence analysisAdd BLAST20
Transmembranei446 – 463Helical; Name=5Sequence analysisAdd BLAST18
Transmembranei504 – 523Helical; Name=6Sequence analysisAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000906041 – 588Putative calcium-binding mitochondrial carrier F55A11.4Add BLAST588

Proteomic databases

EPDiQ20799.
PaxDbiQ20799.

Expressioni

Gene expression databases

BgeeiWBGene00010077.

Interactioni

Protein-protein interaction databases

STRINGi6239.F55A11.4a.

Structurei

3D structure databases

ProteinModelPortaliQ20799.
SMRiQ20799.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 108EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini109 – 139EF-hand 2PROSITE-ProRule annotationAdd BLAST31
Domaini140 – 175EF-hand 3PROSITE-ProRule annotationAdd BLAST36
Domaini176 – 211EF-hand 4PROSITE-ProRule annotationAdd BLAST36
Repeati246 – 332Solcar 1Add BLAST87
Repeati342 – 428Solcar 2Add BLAST87
Repeati440 – 529Solcar 3Add BLAST90

Sequence similaritiesi

Contains 4 EF-hand domains.PROSITE-ProRule annotation
Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0036. Eukaryota.
ENOG410XQ4P. LUCA.
HOGENOMiHOG000165728.
InParanoidiQ20799.

Family and domain databases

CDDicd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 1 hit.
1.50.40.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR002167. Graves_DC.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 1 hit.
PF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00928. GRAVESDC.
PR00926. MITOCARRIER.
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
SSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.
PS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q20799-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINKNEQTES TSGAAEQKED DEEQYVQLSS LGEYKDEVTP LLSPKHVPLV
60 70 80 90 100
LGKVTKEAAI ATHSALHGGM SEEKERQIRD IYDRLDIDND GTIDIRDLTL
110 120 130 140 150
ALKHETPHIP ANLAPVIMSK MSPDDEGRVD FYSFSSYVLE NEQKLAEMFA
160 170 180 190 200
DMDRNHDGLV DVVEMKNYCK DIGVPLDDHK AQHIVNKMDQ TGSASVDLKE
210 220 230 240 250
FQEFMMLYPS SDLKDIVDFW RHNLIIDIGE DSQIPEDFSQ QEMQEGIWWR
260 270 280 290 300
HLVAGGAAGA VSRTCTAPFD RIKVYLQVNS SKTNRLGVMS CLKLLHAEGG
310 320 330 340 350
IKSFWRGNGI NVIKIAPESA IKFMCYDQLK RLIQKKKGNE EISTFERLCA
360 370 380 390 400
GSAAGAISQS TIYPMEVMKT RLALRKTGQL DRGIIHFAHK MYTKEGIRCF
410 420 430 440 450
YKGYLPNLIG IIPYAGIDLA IYETLKRTYV RYYETNSSEP GVLALLACGT
460 470 480 490 500
CSSTCGQLSS YPFALVRTRL QALSITRYSP QPDTMFGQFK YILQNEGVTG
510 520 530 540 550
FYRGITPNFL KVIPAVSISY VVYEKVRTGL GVPVCSRGGL EDIHQFLPCS
560 570 580
IHSIIQFFFF PRTFLLTISG RSLRVKPVWR SHFSKFNK
Length:588
Mass (Da):66,337
Last modified:November 1, 1996 - v1
Checksum:i68DDF60923D8697D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72511 Genomic DNA. No translation available.
PIRiT22688.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72511 Genomic DNA. No translation available.
PIRiT22688.

3D structure databases

ProteinModelPortaliQ20799.
SMRiQ20799.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F55A11.4a.

Proteomic databases

EPDiQ20799.
PaxDbiQ20799.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0036. Eukaryota.
ENOG410XQ4P. LUCA.
HOGENOMiHOG000165728.
InParanoidiQ20799.

Gene expression databases

BgeeiWBGene00010077.

Family and domain databases

CDDicd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 1 hit.
1.50.40.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR002167. Graves_DC.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 1 hit.
PF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00928. GRAVESDC.
PR00926. MITOCARRIER.
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
SSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.
PS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCMC2_CAEEL
AccessioniPrimary (citable) accession number: Q20799
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.