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Protein

Probable cytochrome c oxidase subunit 6A, mitochondrial

Gene

tag-174

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.By similarity

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cytochrome c oxidase subunit 6A, mitochondrial
Alternative name(s):
Cytochrome c oxidase polypeptide VIa
Gene namesi
Name:tag-174
ORF Names:F54D8.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF54D8.2; CE01308; WBGene00006519; tag-174.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial respiratory chain complex IV Source: InterPro
  • mitochondrion Source: WormBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 128Probable cytochrome c oxidase subunit 6A, mitochondrialPRO_0000006125
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

EPDiQ20779.
PaxDbiQ20779.

Interactioni

Protein-protein interaction databases

IntActiQ20779. 1 interaction.
MINTiMINT-3386538.
STRINGi6239.F54D8.2.5.

Structurei

3D structure databases

ProteinModelPortaliQ20779.
SMRiQ20779. Positions 47-122.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3469. Eukaryota.
ENOG411253X. LUCA.
GeneTreeiENSGT00390000002756.
HOGENOMiHOG000193965.
InParanoidiQ20779.
KOiK02266.
OMAiCLALTMY.
PhylomeDBiQ20779.

Family and domain databases

Gene3Di4.10.95.10. 1 hit.
InterProiIPR001349. Cyt_c_oxidase_su6a.
IPR018507. Cyt_c_oxidase_su6a_CS.
[Graphical view]
PANTHERiPTHR11504. PTHR11504. 1 hit.
PfamiPF02046. COX6A. 1 hit.
[Graphical view]
ProDomiPD006036. Cyt_c_oxidase_su6a. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF81411. SSF81411. 1 hit.
PROSITEiPS01329. COX6A. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q20779-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRLAQPATR SVVKTFQRKS SGSFYGSNNV EGFKESYVTP LKQAHNASET
60 70 80 90 100
WKKIFFIASI PCLALTMYAA FKDHKKHMSH ERPEHVEYAF LNVRNKPFPW
110 120
SDGNHSLFHN KAEQFVPGVG FEADREKH
Length:128
Mass (Da):14,743
Last modified:November 1, 1996 - v1
Checksum:iEF4EA56A1CE6A233
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080874 Genomic DNA. Translation: CCD67407.1.
PIRiE88449.
RefSeqiNP_498082.1. NM_065681.5.
UniGeneiCel.18117.

Genome annotation databases

EnsemblMetazoaiF54D8.2.1; F54D8.2.1; WBGene00006519.
F54D8.2.2; F54D8.2.2; WBGene00006519.
F54D8.2.3; F54D8.2.3; WBGene00006519.
F54D8.2.4; F54D8.2.4; WBGene00006519.
F54D8.2.5; F54D8.2.5; WBGene00006519.
GeneIDi175693.
KEGGicel:CELE_F54D8.2.
UCSCiF54D8.2.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080874 Genomic DNA. Translation: CCD67407.1.
PIRiE88449.
RefSeqiNP_498082.1. NM_065681.5.
UniGeneiCel.18117.

3D structure databases

ProteinModelPortaliQ20779.
SMRiQ20779. Positions 47-122.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ20779. 1 interaction.
MINTiMINT-3386538.
STRINGi6239.F54D8.2.5.

Proteomic databases

EPDiQ20779.
PaxDbiQ20779.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF54D8.2.1; F54D8.2.1; WBGene00006519.
F54D8.2.2; F54D8.2.2; WBGene00006519.
F54D8.2.3; F54D8.2.3; WBGene00006519.
F54D8.2.4; F54D8.2.4; WBGene00006519.
F54D8.2.5; F54D8.2.5; WBGene00006519.
GeneIDi175693.
KEGGicel:CELE_F54D8.2.
UCSCiF54D8.2.1. c. elegans.

Organism-specific databases

CTDi175693.
WormBaseiF54D8.2; CE01308; WBGene00006519; tag-174.

Phylogenomic databases

eggNOGiKOG3469. Eukaryota.
ENOG411253X. LUCA.
GeneTreeiENSGT00390000002756.
HOGENOMiHOG000193965.
InParanoidiQ20779.
KOiK02266.
OMAiCLALTMY.
PhylomeDBiQ20779.

Miscellaneous databases

NextBioi889244.
PROiQ20779.

Family and domain databases

Gene3Di4.10.95.10. 1 hit.
InterProiIPR001349. Cyt_c_oxidase_su6a.
IPR018507. Cyt_c_oxidase_su6a_CS.
[Graphical view]
PANTHERiPTHR11504. PTHR11504. 1 hit.
PfamiPF02046. COX6A. 1 hit.
[Graphical view]
ProDomiPD006036. Cyt_c_oxidase_su6a. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF81411. SSF81411. 1 hit.
PROSITEiPS01329. COX6A. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiCOX6A_CAEEL
AccessioniPrimary (citable) accession number: Q20779
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: March 16, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.