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Protein
Submitted name:

Uncharacterized protein

Gene

CELE_F53H8.3

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

TransportSAAS annotation

Enzyme and pathway databases

ReactomeiR-CEL-189200. Hexose transport.
R-CEL-196836. Vitamin C (ascorbate) metabolism.
R-CEL-422356. Regulation of insulin secretion.
R-CEL-428790. Facilitative Na+-independent glucose transporters.
R-CEL-5653890. Lactose synthesis.
R-CEL-6798695. Neutrophil degranulation.
R-CEL-70153. Glucose transport.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:CELE_F53H8.3Imported, F53H8.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiF53H8.3; CE04656; WBGene00018779.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei57 – 79HelicalSequence analysisAdd BLAST23
Transmembranei91 – 111HelicalSequence analysisAdd BLAST21
Transmembranei117 – 138HelicalSequence analysisAdd BLAST22
Transmembranei150 – 170HelicalSequence analysisAdd BLAST21
Transmembranei182 – 201HelicalSequence analysisAdd BLAST20
Transmembranei322 – 346HelicalSequence analysisAdd BLAST25
Transmembranei358 – 382HelicalSequence analysisAdd BLAST25
Transmembranei389 – 411HelicalSequence analysisAdd BLAST23
Transmembranei423 – 446HelicalSequence analysisAdd BLAST24
Transmembranei458 – 478HelicalSequence analysisAdd BLAST21
Transmembranei490 – 508HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiQ20734.
PaxDbiQ20734.
PeptideAtlasiQ20734.

Expressioni

Gene expression databases

BgeeiWBGene00018779.

Interactioni

Protein-protein interaction databases

STRINGi6239.F53H8.3.

Structurei

3D structure databases

ProteinModelPortaliQ20734.
SMRiQ20734.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 512MFSInterPro annotationAdd BLAST504

Sequence similaritiesi

Belongs to the major facilitator superfamily.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0569. Eukaryota.
COG0477. LUCA.
GeneTreeiENSGT00760000119022.
HOGENOMiHOG000018458.
InParanoidiQ20734.
OMAiGILNVFA.
OrthoDBiEOG091G05QZ.
PhylomeDBiQ20734.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 2 hits.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q20734-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTSRYLITV TTVVLGGSAQ FYSYGVVNPA QVVITDWINQ TYIDRYKAPL
60 70 80 90 100
SLTVSNVIWS FVVSSIAIGA ILGASFTRII GEKYGRRNGM FFNGILNVFA
110 120 130 140 150
ALFELVAKRF SSPELLIFGR FVYGINMGLS SGLVPMYLME ITPYKYRGPA
160 170 180 190 200
GTLHQIAVAF SDWFSLLIGL PEVLGDQNNW PLAFALPGLP ALALVCILPF
210 220 230 240 250
CPESPKYTLG TKHDRDKALK DVELLIGKEQ APHMFESIVR EVALDEVSFF
260 270 280 290 300
CVYLYTRISL LGLYLNFANH LATTKFWKKN VIHTALKLKL LSSKLRGNAK
310 320 330 340 350
LHGYFQGDGT FRELFTRPDL RIPLAVSIIV MIAQQFTGCT AVFAFSTDMF
360 370 380 390 400
LNAGLTPVIA RFSTLAIGIV YFLFACTSPF LIHKVGRRWL SLFQLASCMV
410 420 430 440 450
ALMLLSLFTF LQNYENIEWA RYGTIFSLVF YMCVYGVGSP IPWIIASELF
460 470 480 490 500
TQQFRATAVT VSVFVAWTFA FIVSTSYLPF QQLVGITFSY FPFIIGLAVF
510 520 530 540 550
GIFIYVLLPE TRDRPMVEIV TEVHHRTASL SAGRPWDASR PPSRQEVQRL
560
LDTMDPRSYS SYDNSTLED
Length:569
Mass (Da):63,909
Last modified:November 1, 1996 - v1
Checksum:i05CE093D1E316709
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CCD67243.1.
PIRiT34295.
RefSeqiNP_508181.1. NM_075780.5.
UniGeneiCel.896.

Genome annotation databases

EnsemblMetazoaiF53H8.3; F53H8.3; WBGene00018779.
GeneIDi186195.
KEGGicel:CELE_F53H8.3.
UCSCiF53H8.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CCD67243.1.
PIRiT34295.
RefSeqiNP_508181.1. NM_075780.5.
UniGeneiCel.896.

3D structure databases

ProteinModelPortaliQ20734.
SMRiQ20734.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F53H8.3.

Proteomic databases

EPDiQ20734.
PaxDbiQ20734.
PeptideAtlasiQ20734.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF53H8.3; F53H8.3; WBGene00018779.
GeneIDi186195.
KEGGicel:CELE_F53H8.3.
UCSCiF53H8.3. c. elegans.

Organism-specific databases

CTDi186195.
WormBaseiF53H8.3; CE04656; WBGene00018779.

Phylogenomic databases

eggNOGiKOG0569. Eukaryota.
COG0477. LUCA.
GeneTreeiENSGT00760000119022.
HOGENOMiHOG000018458.
InParanoidiQ20734.
OMAiGILNVFA.
OrthoDBiEOG091G05QZ.
PhylomeDBiQ20734.

Enzyme and pathway databases

ReactomeiR-CEL-189200. Hexose transport.
R-CEL-196836. Vitamin C (ascorbate) metabolism.
R-CEL-422356. Regulation of insulin secretion.
R-CEL-428790. Facilitative Na+-independent glucose transporters.
R-CEL-5653890. Lactose synthesis.
R-CEL-6798695. Neutrophil degranulation.
R-CEL-70153. Glucose transport.

Gene expression databases

BgeeiWBGene00018779.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 2 hits.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ20734_CAEEL
AccessioniPrimary (citable) accession number: Q20734
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 133 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.