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Protein
Submitted name:

Uncharacterized protein

Gene

CELE_F53H8.3

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Enzyme and pathway databases

ReactomeiR-CEL-189200. Hexose transport.
R-CEL-196836. Vitamin C (ascorbate) metabolism.
R-CEL-422356. Regulation of insulin secretion.
R-CEL-428790. Facilitative Na+-independent glucose transporters.
R-CEL-5653890. Lactose synthesis.
R-CEL-70153. Glucose transport.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:CELE_F53H8.3Imported, F53H8.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiF53H8.3; CE04656; WBGene00018779.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei57 – 7923HelicalSequence analysisAdd
BLAST
Transmembranei91 – 11121HelicalSequence analysisAdd
BLAST
Transmembranei117 – 13822HelicalSequence analysisAdd
BLAST
Transmembranei150 – 17021HelicalSequence analysisAdd
BLAST
Transmembranei182 – 20120HelicalSequence analysisAdd
BLAST
Transmembranei322 – 34625HelicalSequence analysisAdd
BLAST
Transmembranei358 – 38225HelicalSequence analysisAdd
BLAST
Transmembranei389 – 41123HelicalSequence analysisAdd
BLAST
Transmembranei423 – 44624HelicalSequence analysisAdd
BLAST
Transmembranei458 – 47821HelicalSequence analysisAdd
BLAST
Transmembranei490 – 50819HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiQ20734.
PaxDbiQ20734.
PRIDEiQ20734.

Interactioni

Protein-protein interaction databases

STRINGi6239.F53H8.3.

Structurei

3D structure databases

ProteinModelPortaliQ20734.
SMRiQ20734. Positions 2-527.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 512504MFSInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the major facilitator superfamily.SAAS annotation
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0569. Eukaryota.
COG0477. LUCA.
GeneTreeiENSGT00760000119022.
HOGENOMiHOG000018458.
InParanoidiQ20734.
OMAiGILNVFA.
OrthoDBiEOG7B31NC.
PhylomeDBiQ20734.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 2 hits.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q20734-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTSRYLITV TTVVLGGSAQ FYSYGVVNPA QVVITDWINQ TYIDRYKAPL
60 70 80 90 100
SLTVSNVIWS FVVSSIAIGA ILGASFTRII GEKYGRRNGM FFNGILNVFA
110 120 130 140 150
ALFELVAKRF SSPELLIFGR FVYGINMGLS SGLVPMYLME ITPYKYRGPA
160 170 180 190 200
GTLHQIAVAF SDWFSLLIGL PEVLGDQNNW PLAFALPGLP ALALVCILPF
210 220 230 240 250
CPESPKYTLG TKHDRDKALK DVELLIGKEQ APHMFESIVR EVALDEVSFF
260 270 280 290 300
CVYLYTRISL LGLYLNFANH LATTKFWKKN VIHTALKLKL LSSKLRGNAK
310 320 330 340 350
LHGYFQGDGT FRELFTRPDL RIPLAVSIIV MIAQQFTGCT AVFAFSTDMF
360 370 380 390 400
LNAGLTPVIA RFSTLAIGIV YFLFACTSPF LIHKVGRRWL SLFQLASCMV
410 420 430 440 450
ALMLLSLFTF LQNYENIEWA RYGTIFSLVF YMCVYGVGSP IPWIIASELF
460 470 480 490 500
TQQFRATAVT VSVFVAWTFA FIVSTSYLPF QQLVGITFSY FPFIIGLAVF
510 520 530 540 550
GIFIYVLLPE TRDRPMVEIV TEVHHRTASL SAGRPWDASR PPSRQEVQRL
560
LDTMDPRSYS SYDNSTLED
Length:569
Mass (Da):63,909
Last modified:November 1, 1996 - v1
Checksum:i05CE093D1E316709
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CCD67243.1.
PIRiT34295.
RefSeqiNP_508181.1. NM_075780.5.
UniGeneiCel.896.

Genome annotation databases

EnsemblMetazoaiF53H8.3; F53H8.3; WBGene00018779.
GeneIDi186195.
KEGGicel:CELE_F53H8.3.
UCSCiF53H8.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CCD67243.1.
PIRiT34295.
RefSeqiNP_508181.1. NM_075780.5.
UniGeneiCel.896.

3D structure databases

ProteinModelPortaliQ20734.
SMRiQ20734. Positions 2-527.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F53H8.3.

Proteomic databases

EPDiQ20734.
PaxDbiQ20734.
PRIDEiQ20734.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF53H8.3; F53H8.3; WBGene00018779.
GeneIDi186195.
KEGGicel:CELE_F53H8.3.
UCSCiF53H8.3. c. elegans.

Organism-specific databases

CTDi186195.
WormBaseiF53H8.3; CE04656; WBGene00018779.

Phylogenomic databases

eggNOGiKOG0569. Eukaryota.
COG0477. LUCA.
GeneTreeiENSGT00760000119022.
HOGENOMiHOG000018458.
InParanoidiQ20734.
OMAiGILNVFA.
OrthoDBiEOG7B31NC.
PhylomeDBiQ20734.

Enzyme and pathway databases

ReactomeiR-CEL-189200. Hexose transport.
R-CEL-196836. Vitamin C (ascorbate) metabolism.
R-CEL-422356. Regulation of insulin secretion.
R-CEL-428790. Facilitative Na+-independent glucose transporters.
R-CEL-5653890. Lactose synthesis.
R-CEL-70153. Glucose transport.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 2 hits.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ20734_CAEEL
AccessioniPrimary (citable) accession number: Q20734
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 8, 2016
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.