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Q20605 (AMT2_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified September 21, 2011. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative ammonium transporter 2
Gene names
Name:amt-2
ORF Names:F49E11.3
OrganismCaenorhabditis elegans
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length505 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Involved in the uptake of ammonia Probable.

Subcellular location

Membrane; Multi-pass membrane protein Probable.

Sequence similarities

Belongs to the ammonia transporter channel (TC 1.A.11.2) family. [View classification]

Ontologies

Keywords
   Biological processAmmonia transport
Transport
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processdetermination of adult lifespan

Inferred from mutant phenotype. Source: WormBase

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionammonium transmembrane transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 505505Putative ammonium transporter 2
PRO_0000139752

Regions

Transmembrane24 – 4421Helical; Potential
Transmembrane62 – 8221Helical; Potential
Transmembrane114 – 13421Helical; Potential
Transmembrane146 – 16621Helical; Potential
Transmembrane181 – 20121Helical; Potential
Transmembrane216 – 23621Helical; Potential
Transmembrane256 – 27621Helical; Potential
Transmembrane281 – 30121Helical; Potential
Transmembrane311 – 32717Helical; Potential
Transmembrane336 – 35621Helical; Potential
Transmembrane371 – 39121Helical; Potential
Transmembrane394 – 41421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q20605 [UniParc].

Last modified July 10, 2007. Version 2.
Checksum: 6E68B94966A8C57C

FASTA50555,683
        10         20         30         40         50         60 
MDRQPTIRMK PDKQLDCSLS QDDGVWMMAS SFIIFTMTAG FGLLESGRVS SKDEVNCMVK 

        70         80         90        100        110        120 
NVFDVIFGGL AYWMFGYGLT FGDSKHQLGR YVGFGDFFFD PERVSDDDST DEKGISYSLF 

       130        140        150        160        170        180 
IFQMSFATTT STIVSAGMSE RIHLKSHCFI SFFITLVHSV AGHWVWDQEG VFRMMGVVDS 

       190        200        210        220        230        240 
AGCSAVHLVG GVSGLVATLY LKPRRNRFAK NGIRTVSDPT KAILGFLMIW WGWLAFNTSS 

       250        260        270        280        290        300 
NYAVTHGQWT EGMRSAVGTI LASAGGGVVT VIITRLSTKK IQMDMLIDGM LASLVASTGG 

       310        320        330        340        350        360 
CLYFTPWQAT LVGAIGSSLA LAAYPVTEWL KIDDPVGVFP VHVVGSIWGM IAPAIFVYRR 

       370        380        390        400        410        420 
PMNFGPPECD FQTSDEINGL LYGGGFYLLF LQSFVILVIG TYSAICAFII LFLIHHSPVG 

       430        440        450        460        470        480 
LRVDKYTEEL GADLIEHGLA GFNVMTYTIE KKLDTKTLSA VLMIIVRWRA KAKLGAQRRK 

       490        500 
KIHDSGSVAP QQAESVEMNV IHRRH

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Z70308 Genomic DNA. Translation: CAA94345.2.
PIRT22433.
RefSeqNP_502496.2. NM_070095.2.
UniGeneCel.2458.

3D structure databases

ProteinModelPortalQ20605.
SMRQ20605. Positions 19-443.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaF49E11.3; F49E11.3; F49E11.3.
GeneID186047.
KEGGcel:F49E11.3.
UCSCF49E11.3. c. elegans.

Organism-specific databases

CTD186047.
WormBaseF49E11.3; CE40457; WBGene00000134; amt-2.

Phylogenomic databases

eggNOGmeNOG07036.
GeneTreeEMGT00050000009536.
HOGENOMHBG677626.
InParanoidQ20605.
OMAYSAICAF.
PhylomeDBQ20605.

Gene expression databases

ArrayExpressQ20605.

Family and domain databases

InterProIPR001905. Ammonium_transpt.
IPR018047. Ammonium_transpt_CS.
IPR024041. NH4_transpt_AmtB-like.
[Graphical view]
Gene3DG3DSA:1.10.3430.10. G3DSA:1.10.3430.10. 1 hit.
PANTHERPTHR11730. Ammonium_transpt. 1 hit.
PfamPF00909. Ammonium_transp. 1 hit.
[Graphical view]
SUPFAMSSF111352. RH_like_transpt. 1 hit.
TIGRFAMsTIGR00836. Amt. 1 hit.
PROSITEPS01219. AMMONIUM_TRANSP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio930450.

Entry information

Entry nameAMT2_CAEEL
AccessionPrimary (citable) accession number: Q20605
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 10, 2007
Last modified: September 21, 2011
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormPep

SIMILARITY comments

Index of protein domains and families

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