Q20507 (ACBP3_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acyl-CoA-binding protein homolog 3
Short name=ACBP-3

Gene names

Name:	acbp-3
ORF Names:	F47B10.7

Organism

Caenorhabditis elegans [Reference proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	116 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters By similarity.
Sequence similarities	Belongs to the ACBP family. Contains 1 ACB (acyl-CoA-binding) domain.

Ontologies

Keywords
Biological process	Transport
Ligand	Lipid-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	lipid storage Inferred from mutant phenotype PubMed 21539519. Source: WormBase transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	fatty-acyl-CoA binding Inferred from electronic annotation. Source: InterPro lipid binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 116	116	Acyl-CoA-binding protein homolog 3		PRO_0000214026
Regions
	Domain	3 – 92	90	ACB
	Region	34 – 38	5	Acyl-CoA binding By similarity
Sites
	Binding site	60	1	Acyl-CoA By similarity
	Binding site	79	1	Acyl-CoA By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q20507 [UniParc]. Last modified April 11, 2003. Version 2. Checksum: D2BDE14AC1784FF2	FASTA	116	13,174
	10 20 30 40 50 60 MSLQEKFDAA VEIIQKLPKT GPVATSNDQK LTFYSLFKQA SIGDVNTDRP GIFSIIERKK 70 80 90 100 110 WDSWKELEGV SQDEAKERYI KALNDMFDKI AEELDVAAWL EQIDPVIKTN LALIGK

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z68004 Genomic DNA. Translation: CAA91987.2.
PIR	T22338.
RefSeq	NP_509822.2. NM_077421.5.
3D structure databases
ProteinModelPortal	Q20507.
SMR	Q20507. Positions 4-93.
ModBase	Search...
Protein-protein interaction databases
STRING	6239.F47B10.7.
Proteomic databases
PaxDb	Q20507.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	F47B10.7; F47B10.7; F47B10.7.
GeneID	181281.
KEGG	cel:CELE_F47B10.7.
UCSC	F47B10.7. c. elegans.
Organism-specific databases
CTD	181281.
WormBase	F47B10.7; CE32423; WBGene00009818; acbp-3.
Phylogenomic databases
eggNOG	COG4281.
GeneTree	ENSGT00680000099745.
HOGENOM	HOG000261845.
InParanoid	Q20507.
OMA	EAKERYI.
Family and domain databases
Gene3D	1.20.80.10. 1 hit.
InterPro	IPR022408. Acyl-CoA-binding_prot_CS. IPR000582. Acyl-CoA-binding_protein. IPR014352. FERM/acyl-CoA-bd_prot_3-hlx. [Graphical view]
Pfam	PF00887. ACBP. 1 hit. [Graphical view]
PRINTS	PR00689. ACOABINDINGP.
SUPFAM	SSF47027. ACBP. 1 hit.
PROSITE	PS00880. ACB_1. 1 hit. PS51228. ACB_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	913264.

Entry information

Entry name

ACBP3_CAEEL

Accession

Primary (citable) accession number: Q20507

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	April 11, 2003
Last modified:	May 1, 2013
This is version 84 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Caenorhabditis annotation project