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Protein

Acyl-CoA-binding protein homolog 3

Gene

acbp-3

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei60Acyl-CoABy similarity1
Binding sitei79Acyl-CoABy similarity1

GO - Molecular functioni

GO - Biological processi

  • lipid storage Source: WormBase
  • transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Lipid-binding

Enzyme and pathway databases

ReactomeiR-CEL-390918. Peroxisomal lipid metabolism.

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl-CoA-binding protein homolog 3
Short name:
ACBP-3
Gene namesi
Name:acbp-3
ORF Names:F47B10.7
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiF47B10.7; CE32423; WBGene00009818; acbp-3.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002140261 – 116Acyl-CoA-binding protein homolog 3Add BLAST116

Proteomic databases

EPDiQ20507.
PaxDbiQ20507.
PeptideAtlasiQ20507.
PRIDEiQ20507.

Expressioni

Gene expression databases

BgeeiWBGene00009818.

Interactioni

Protein-protein interaction databases

STRINGi6239.F47B10.7.

Structurei

3D structure databases

ProteinModelPortaliQ20507.
SMRiQ20507.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 92ACBPROSITE-ProRule annotationAdd BLAST90

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni34 – 38Acyl-CoA bindingBy similarity5

Sequence similaritiesi

Belongs to the ACBP family.Curated
Contains 1 ACB (acyl-CoA-binding) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0817. Eukaryota.
COG4281. LUCA.
GeneTreeiENSGT00840000129776.
HOGENOMiHOG000261845.
InParanoidiQ20507.
OMAiALNDMFD.
OrthoDBiEOG091G0NXJ.
PhylomeDBiQ20507.

Family and domain databases

Gene3Di1.20.80.10. 1 hit.
InterProiIPR022408. Acyl-CoA-binding_prot_CS.
IPR000582. Acyl-CoA-binding_protein.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
[Graphical view]
PfamiPF00887. ACBP. 1 hit.
[Graphical view]
PRINTSiPR00689. ACOABINDINGP.
SUPFAMiSSF47027. SSF47027. 1 hit.
PROSITEiPS00880. ACB_1. 1 hit.
PS51228. ACB_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q20507-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLQEKFDAA VEIIQKLPKT GPVATSNDQK LTFYSLFKQA SIGDVNTDRP
60 70 80 90 100
GIFSIIERKK WDSWKELEGV SQDEAKERYI KALNDMFDKI AEELDVAAWL
110
EQIDPVIKTN LALIGK
Length:116
Mass (Da):13,174
Last modified:April 11, 2003 - v2
Checksum:iD2BDE14AC1784FF2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68004 Genomic DNA. Translation: CAA91987.2.
PIRiT22338.
RefSeqiNP_509822.2. NM_077421.5.
UniGeneiCel.975.

Genome annotation databases

EnsemblMetazoaiF47B10.7; F47B10.7; WBGene00009818.
GeneIDi181281.
KEGGicel:CELE_F47B10.7.
UCSCiF47B10.7. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68004 Genomic DNA. Translation: CAA91987.2.
PIRiT22338.
RefSeqiNP_509822.2. NM_077421.5.
UniGeneiCel.975.

3D structure databases

ProteinModelPortaliQ20507.
SMRiQ20507.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F47B10.7.

Proteomic databases

EPDiQ20507.
PaxDbiQ20507.
PeptideAtlasiQ20507.
PRIDEiQ20507.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF47B10.7; F47B10.7; WBGene00009818.
GeneIDi181281.
KEGGicel:CELE_F47B10.7.
UCSCiF47B10.7. c. elegans.

Organism-specific databases

CTDi181281.
WormBaseiF47B10.7; CE32423; WBGene00009818; acbp-3.

Phylogenomic databases

eggNOGiKOG0817. Eukaryota.
COG4281. LUCA.
GeneTreeiENSGT00840000129776.
HOGENOMiHOG000261845.
InParanoidiQ20507.
OMAiALNDMFD.
OrthoDBiEOG091G0NXJ.
PhylomeDBiQ20507.

Enzyme and pathway databases

ReactomeiR-CEL-390918. Peroxisomal lipid metabolism.

Miscellaneous databases

PROiQ20507.

Gene expression databases

BgeeiWBGene00009818.

Family and domain databases

Gene3Di1.20.80.10. 1 hit.
InterProiIPR022408. Acyl-CoA-binding_prot_CS.
IPR000582. Acyl-CoA-binding_protein.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
[Graphical view]
PfamiPF00887. ACBP. 1 hit.
[Graphical view]
PRINTSiPR00689. ACOABINDINGP.
SUPFAMiSSF47027. SSF47027. 1 hit.
PROSITEiPS00880. ACB_1. 1 hit.
PS51228. ACB_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiACBP3_CAEEL
AccessioniPrimary (citable) accession number: Q20507
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: April 11, 2003
Last modified: November 2, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.