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Protein

Calsequestrin

Gene

csq-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.UniRule annotation

GO - Molecular functioni

  • calcium ion binding Source: WormBase

GO - Biological processi

  • calcium ion homeostasis Source: WormBase

Keywordsi

LigandCalciumUniRule annotation

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.
R-CEL-5578775. Ion homeostasis.

Names & Taxonomyi

Protein namesi
Recommended name:
CalsequestrinUniRule annotation
Gene namesi
Name:csq-1Imported
ORF Names:CELE_F40E10.3Imported, F40E10.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiF40E10.3; CE05839; WBGene00000822; csq-1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500419924819 – 417CalsequestrinSequence analysisAdd BLAST399

Proteomic databases

EPDiQ20203.
PaxDbiQ20203.
PeptideAtlasiQ20203.

Expressioni

Gene expression databases

BgeeiWBGene00000822.

Interactioni

Protein-protein interaction databases

IntActiQ20203. 1 interactor.
STRINGi6239.F40E10.3.2.

Structurei

3D structure databases

ProteinModelPortaliQ20203.
SMRiQ20203.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the calsequestrin family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IGY5. Eukaryota.
ENOG4111R2M. LUCA.
GeneTreeiENSGT00390000019377.
HOGENOMiHOG000018341.
InParanoidiQ20203.
OMAiTWEDDLN.
OrthoDBiEOG091G08VX.
PhylomeDBiQ20203.

Family and domain databases

InterProiView protein in InterPro
IPR001393. Calsequestrin.
IPR036249. Thioredoxin-like_sf.
PANTHERiPTHR10033. PTHR10033. 1 hit.
PfamiView protein in Pfam
PF01216. Calsequestrin. 1 hit.
SUPFAMiSSF52833. SSF52833. 3 hits.

Sequencei

Sequence statusi: Complete.

Q20203-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTWIKLASLA LVVVLASAGI SKNEDLECMF LGYPDLEYDG FDRTEVLTEK
60 70 80 90 100
NFNRTVFAED TKSVVFFNDV EEDDSELDQY ECFLQLSAQI MTKRGYNFYT
110 120 130 140 150
VNTTKEHRLR KQEEVEKGED TIHVYKDGYK IEYNGVRDPE TFVSWLMDIP
160 170 180 190 200
DDPVTIINDE HDLEEFENMD DECVRIIGYF EPGSVALKEF EEAAEDFMGE
210 220 230 240 250
IEFFAVVTSK WARKVGLKRV GEVQMRRPFE EDPLFAPTSA DTEEEFEDWV
260 270 280 290 300
EKNKEPVMQK LTLDNYFNLW RDPEEEERMI LAFVDEETRE GRAMKRLLDK
310 320 330 340 350
IADENSEHAG TLEIILVDPD EFPLMVDVWE DMFGIDIEEG PQIGLIDISE
360 370 380 390 400
KEGIWFDMSQ VNLDDPKKHS DSNFEALQSW IDQILSGSIS LDDDDDDEPE
410
PPAPPPTPKG KKSRKEL
Length:417
Mass (Da):48,327
Last modified:November 1, 1996 - v1
Checksum:i02B52D4CDBC92BA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAA93667.1.
PIRiT22024.
RefSeqiNP_510438.1. NM_078037.4.
UniGeneiCel.5077.

Genome annotation databases

EnsemblMetazoaiF40E10.3; F40E10.3; WBGene00000822.
GeneIDi181563.
KEGGicel:CELE_F40E10.3.
UCSCiF40E10.3.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ20203_CAEEL
AccessioniPrimary (citable) accession number: Q20203
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 25, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported