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Protein
Submitted name:

Fatty Acid CoA Synthetase family

Gene

acs-4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-CEL-75876. Synthesis of very long-chain fatty acyl-CoAs.

Names & Taxonomyi

Protein namesi
Submitted name:
Fatty Acid CoA Synthetase familyImported
Gene namesi
Name:acs-4Imported
ORF Names:CELE_F37C12.7Imported, F37C12.7Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF37C12.7; CE29312; WBGene00018152; acs-4.

Subcellular locationi

GO - Cellular componenti

  • lipid particle Source: WormBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiQ20121.
PaxDbiQ20121.
PRIDEiQ20121.

Expressioni

Gene expression databases

BgeeiWBGene00018152.

Interactioni

Protein-protein interaction databases

STRINGi6239.F37C12.7.

Structurei

3D structure databases

ProteinModelPortaliQ20121.
SMRiQ20121. Positions 143-685.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini123 – 593471AMP-bindingInterPro annotationAdd
BLAST
Domaini603 – 69189AMP-binding_CInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1256. Eukaryota.
COG1022. LUCA.
GeneTreeiENSGT00820000127049.
HOGENOMiHOG000159459.
InParanoidiQ20121.
KOiK01897.
OMAiACVADIN.
OrthoDBiEOG091G02F4.
PhylomeDBiQ20121.

Family and domain databases

InterProiIPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q20121-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRKVSVYDS SKDKTLGQVV KGESPIWIRV AMAILRVWFF IYDCLNYLPY
60 70 80 90 100
QLFNSPTEKL RKSERVKANW VDDRDGPIRN IQGHASETFP GKDTVDKVWR
110 120 130 140 150
KCVELYDESP CLGTRQLIEV HEDKQPGGRV FEKWHLGEYV WQSYKEVETQ
160 170 180 190 200
VARLAAGIKD LAHEEQNPKV VIFAETRADW LITALACFRA NVTIVTVYAT
210 220 230 240 250
LGEDAIAHAI GETEATILVT SSELLPKIVT LGKKCPTLKT LIYFAPVDQK
260 270 280 290 300
APAPELAPFR DQFKHVLSLS GLLTRNQEQV KESTAVKSDI ALIMYTSGTT
310 320 330 340 350
GQPKGVILLH QNVVAALLGQ GDGVGIICNA DTYIGYLPLA HILELDAELT
360 370 380 390 400
CLTKGAKVGY SSPLTLHDRA SKIQKGTHGD CHALRPTLMA AVPAIMDRIF
410 420 430 440 450
KAVSEEVAAS PRFMQELFKL NYERKRSRYL EGYCSPFLDR IVFKKIRRLL
460 470 480 490 500
GGKLRGVLSG GAPLNAETQR FMNICMCCPV VQGYGLTETC GAACVADIND
510 520 530 540 550
LSTGTVGPPV RCSDIALREW SEGGYSPFND PPQGEILISG ENISPGYYKQ
560 570 580 590 600
PEKTAEDFIT YKGKVYFATG DIGQKRDDGS LLIIDRKKDL VKLQHGEYVS
610 620 630 640 650
LAKVECALLN CPIVDNICVY GSGMEDSVVA LVVPNQKHLE KIAEAEGVST
660 670 680 690 700
SEMKTMCEDK KVIAAYKKQL EEHAKKSKLS RSEIPAAIHL CPEIWTPDTG
710 720 730
LLTEALKLKR KPIQMAYQKT LDDLYKQLKK N
Length:731
Mass (Da):81,253
Last modified:October 1, 2001 - v2
Checksum:i1F317B9D899C5FC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD70738.1.
PIRiT28829.
RefSeqiNP_498568.1. NM_066167.5.
UniGeneiCel.5646.

Genome annotation databases

EnsemblMetazoaiF37C12.7; F37C12.7; WBGene00018152.
GeneIDi176005.
KEGGicel:CELE_F37C12.7.
UCSCiF37C12.7. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD70738.1.
PIRiT28829.
RefSeqiNP_498568.1. NM_066167.5.
UniGeneiCel.5646.

3D structure databases

ProteinModelPortaliQ20121.
SMRiQ20121. Positions 143-685.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F37C12.7.

Proteomic databases

EPDiQ20121.
PaxDbiQ20121.
PRIDEiQ20121.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF37C12.7; F37C12.7; WBGene00018152.
GeneIDi176005.
KEGGicel:CELE_F37C12.7.
UCSCiF37C12.7. c. elegans.

Organism-specific databases

CTDi176005.
WormBaseiF37C12.7; CE29312; WBGene00018152; acs-4.

Phylogenomic databases

eggNOGiKOG1256. Eukaryota.
COG1022. LUCA.
GeneTreeiENSGT00820000127049.
HOGENOMiHOG000159459.
InParanoidiQ20121.
KOiK01897.
OMAiACVADIN.
OrthoDBiEOG091G02F4.
PhylomeDBiQ20121.

Enzyme and pathway databases

ReactomeiR-CEL-75876. Synthesis of very long-chain fatty acyl-CoAs.

Gene expression databases

BgeeiWBGene00018152.

Family and domain databases

InterProiIPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ20121_CAEEL
AccessioniPrimary (citable) accession number: Q20121
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: October 1, 2001
Last modified: September 7, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.