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Protein

Putative UDP-glucuronosyltransferase ugt-58

Gene

ugt-58

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

GO - Molecular functioni

  1. glucuronosyltransferase activity Source: GO_Central

GO - Biological processi

  1. flavonoid biosynthetic process Source: GO_Central
  2. flavonoid glucuronidation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative UDP-glucuronosyltransferase ugt-58 (EC:2.4.1.17)
Short name:
UDPGT 58
Gene namesi
Name:ugt-58
Synonyms:ugt5
ORF Names:F35H8.6
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome II

Organism-specific databases

WormBaseiF35H8.6; CE00984; WBGene00009450; ugt-58.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei481 – 50121HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. intracellular membrane-bounded organelle Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence AnalysisAdd
BLAST
Chaini17 – 533517Putative UDP-glucuronosyltransferase ugt-58PRO_0000036050Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi88 – 881N-linked (GlcNAc...)Sequence Analysis
Glycosylationi243 – 2431N-linked (GlcNAc...)Sequence Analysis
Glycosylationi336 – 3361N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ20086.

Interactioni

Protein-protein interaction databases

STRINGi6239.F35H8.6.

Structurei

3D structure databases

ProteinModelPortaliQ20086.
SMRiQ20086. Positions 328-433.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG247080.
GeneTreeiENSGT00760000118949.
HOGENOMiHOG000016218.
InParanoidiQ20086.
KOiK00699.
OMAiHIVQPRI.
PhylomeDBiQ20086.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q20086-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKSWLLLLGT IGWVTAGDVL FIPSTLYPVH AQTMSVLARE LAERGHKVTW
60 70 80 90 100
LEIGPERSDI VLHQQVSREF WPAQFGDRTL QEIYQFKNHT SHSELWNPQY
110 120 130 140 150
TNENEQTTGW LASIRLCDSV LSRSKSKFDK MVEKQFSTVI VDDLYNSCGV
160 170 180 190 200
LMAGLKKSVY IYWSMTGLRT ESAWANQSPS PPSYLPVAGT GLTDDLTFSQ
210 220 230 240 250
RLYNVASYFK QLYIHQHIVQ PRIDAVFQKY YPGVESTFEI ERNASINFVN
260 270 280 290 300
TPPIFDFSRP YMPRVNFIGA IQCRKPKELP KEFTSWISAY PDGFVVLSTG
310 320 330 340 350
FTVQWNKSPE HIRQAYLDTF KYLPNLLFIW QTGLPNSSNL PSNLLVKPWL
360 370 380 390 400
PLQDLLGHQK CRCHVSHGGL NSVIESVYHG VPVVGVPLTS RGYDNLLRIT
410 420 430 440 450
ARDSGVMVEK SEFSGEILTA AINEVIENEK YKKEMLIFQD MVIDVPYTEL
460 470 480 490 500
YHAAFWVEFI ERHQEVPHAR SGADHLNFLQ YFLVDVIAFF FFVIFCTLSI
510 520 530
IYYTIRTVFR TIRSVVNGVR GVPKIVSRGK KNN
Length:533
Mass (Da):61,143
Last modified:December 6, 2002 - v2
Checksum:iB094511E73D55D46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z36752 Genomic DNA. Translation: CAA85328.2.
PIRiT21823.
RefSeqiNP_496059.2. NM_063658.6.
UniGeneiCel.17672.

Genome annotation databases

EnsemblMetazoaiF35H8.6; F35H8.6; WBGene00009450.
GeneIDi174507.
KEGGicel:CELE_F35H8.6.
UCSCiF35H8.6. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z36752 Genomic DNA. Translation: CAA85328.2.
PIRiT21823.
RefSeqiNP_496059.2. NM_063658.6.
UniGeneiCel.17672.

3D structure databases

ProteinModelPortaliQ20086.
SMRiQ20086. Positions 328-433.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F35H8.6.

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Proteomic databases

PaxDbiQ20086.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF35H8.6; F35H8.6; WBGene00009450.
GeneIDi174507.
KEGGicel:CELE_F35H8.6.
UCSCiF35H8.6. c. elegans.

Organism-specific databases

CTDi174507.
WormBaseiF35H8.6; CE00984; WBGene00009450; ugt-58.

Phylogenomic databases

eggNOGiNOG247080.
GeneTreeiENSGT00760000118949.
HOGENOMiHOG000016218.
InParanoidiQ20086.
KOiK00699.
OMAiHIVQPRI.
PhylomeDBiQ20086.

Miscellaneous databases

NextBioi884324.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiUGT58_CAEEL
AccessioniPrimary (citable) accession number: Q20086
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 6, 2002
Last modified: February 4, 2015
This is version 95 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.