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Q20086

- UGT58_CAEEL

UniProt

Q20086 - UGT58_CAEEL

Protein

Putative UDP-glucuronosyltransferase ugt-58

Gene

ugt-58

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 2 (06 Dec 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

    GO - Molecular functioni

    1. glucuronosyltransferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Protein family/group databases

    CAZyiGT1. Glycosyltransferase Family 1.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative UDP-glucuronosyltransferase ugt-58 (EC:2.4.1.17)
    Short name:
    UDPGT 58
    Gene namesi
    Name:ugt-58
    Synonyms:ugt5
    ORF Names:F35H8.6
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome II

    Organism-specific databases

    WormBaseiF35H8.6; CE00984; WBGene00009450; ugt-58.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1616Sequence AnalysisAdd
    BLAST
    Chaini17 – 533517Putative UDP-glucuronosyltransferase ugt-58PRO_0000036050Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi88 – 881N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi243 – 2431N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi336 – 3361N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ20086.

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.F35H8.6.

    Structurei

    3D structure databases

    ProteinModelPortaliQ20086.
    SMRiQ20086. Positions 328-433.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei481 – 50121HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UDP-glycosyltransferase family.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG247080.
    GeneTreeiENSGT00560000076760.
    HOGENOMiHOG000016218.
    InParanoidiQ20086.
    KOiK00699.
    OMAiHIVQPRI.
    PhylomeDBiQ20086.

    Family and domain databases

    InterProiIPR002213. UDP_glucos_trans.
    [Graphical view]
    PANTHERiPTHR11926. PTHR11926. 1 hit.
    PfamiPF00201. UDPGT. 1 hit.
    [Graphical view]
    PROSITEiPS00375. UDPGT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q20086-1 [UniParc]FASTAAdd to Basket

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    MKSWLLLLGT IGWVTAGDVL FIPSTLYPVH AQTMSVLARE LAERGHKVTW    50
    LEIGPERSDI VLHQQVSREF WPAQFGDRTL QEIYQFKNHT SHSELWNPQY 100
    TNENEQTTGW LASIRLCDSV LSRSKSKFDK MVEKQFSTVI VDDLYNSCGV 150
    LMAGLKKSVY IYWSMTGLRT ESAWANQSPS PPSYLPVAGT GLTDDLTFSQ 200
    RLYNVASYFK QLYIHQHIVQ PRIDAVFQKY YPGVESTFEI ERNASINFVN 250
    TPPIFDFSRP YMPRVNFIGA IQCRKPKELP KEFTSWISAY PDGFVVLSTG 300
    FTVQWNKSPE HIRQAYLDTF KYLPNLLFIW QTGLPNSSNL PSNLLVKPWL 350
    PLQDLLGHQK CRCHVSHGGL NSVIESVYHG VPVVGVPLTS RGYDNLLRIT 400
    ARDSGVMVEK SEFSGEILTA AINEVIENEK YKKEMLIFQD MVIDVPYTEL 450
    YHAAFWVEFI ERHQEVPHAR SGADHLNFLQ YFLVDVIAFF FFVIFCTLSI 500
    IYYTIRTVFR TIRSVVNGVR GVPKIVSRGK KNN 533
    Length:533
    Mass (Da):61,143
    Last modified:December 6, 2002 - v2
    Checksum:iB094511E73D55D46
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z36752 Genomic DNA. Translation: CAA85328.2.
    PIRiT21823.
    RefSeqiNP_496059.2. NM_063658.6.
    UniGeneiCel.17672.

    Genome annotation databases

    EnsemblMetazoaiF35H8.6; F35H8.6; WBGene00009450.
    GeneIDi174507.
    KEGGicel:CELE_F35H8.6.
    UCSCiF35H8.6. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z36752 Genomic DNA. Translation: CAA85328.2 .
    PIRi T21823.
    RefSeqi NP_496059.2. NM_063658.6.
    UniGenei Cel.17672.

    3D structure databases

    ProteinModelPortali Q20086.
    SMRi Q20086. Positions 328-433.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.F35H8.6.

    Protein family/group databases

    CAZyi GT1. Glycosyltransferase Family 1.

    Proteomic databases

    PaxDbi Q20086.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai F35H8.6 ; F35H8.6 ; WBGene00009450 .
    GeneIDi 174507.
    KEGGi cel:CELE_F35H8.6.
    UCSCi F35H8.6. c. elegans.

    Organism-specific databases

    CTDi 174507.
    WormBasei F35H8.6 ; CE00984 ; WBGene00009450 ; ugt-58.

    Phylogenomic databases

    eggNOGi NOG247080.
    GeneTreei ENSGT00560000076760.
    HOGENOMi HOG000016218.
    InParanoidi Q20086.
    KOi K00699.
    OMAi HIVQPRI.
    PhylomeDBi Q20086.

    Miscellaneous databases

    NextBioi 884324.

    Family and domain databases

    InterProi IPR002213. UDP_glucos_trans.
    [Graphical view ]
    PANTHERi PTHR11926. PTHR11926. 1 hit.
    Pfami PF00201. UDPGT. 1 hit.
    [Graphical view ]
    PROSITEi PS00375. UDPGT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiUGT58_CAEEL
    AccessioniPrimary (citable) accession number: Q20086
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: December 6, 2002
    Last modified: October 1, 2014
    This is version 92 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3