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Q20086 (UGT58_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative UDP-glucuronosyltransferase ugt-58

Short name=UDPGT 58
EC=2.4.1.17
Gene names
Name:ugt-58
Synonyms:ugt5
ORF Names:F35H8.6
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length533 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the UDP-glycosyltransferase family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal
Transmembrane
Transmembrane helix
   Molecular functionGlycosyltransferase
Transferase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionglucuronosyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1616 Potential
Chain17 – 533517Putative UDP-glucuronosyltransferase ugt-58
PRO_0000036050

Regions

Transmembrane481 – 50121Helical; Potential

Amino acid modifications

Glycosylation881N-linked (GlcNAc...) Potential
Glycosylation2431N-linked (GlcNAc...) Potential
Glycosylation3361N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q20086 [UniParc].

Last modified December 6, 2002. Version 2.
Checksum: B094511E73D55D46

FASTA53361,143
        10         20         30         40         50         60 
MKSWLLLLGT IGWVTAGDVL FIPSTLYPVH AQTMSVLARE LAERGHKVTW LEIGPERSDI 

        70         80         90        100        110        120 
VLHQQVSREF WPAQFGDRTL QEIYQFKNHT SHSELWNPQY TNENEQTTGW LASIRLCDSV 

       130        140        150        160        170        180 
LSRSKSKFDK MVEKQFSTVI VDDLYNSCGV LMAGLKKSVY IYWSMTGLRT ESAWANQSPS 

       190        200        210        220        230        240 
PPSYLPVAGT GLTDDLTFSQ RLYNVASYFK QLYIHQHIVQ PRIDAVFQKY YPGVESTFEI 

       250        260        270        280        290        300 
ERNASINFVN TPPIFDFSRP YMPRVNFIGA IQCRKPKELP KEFTSWISAY PDGFVVLSTG 

       310        320        330        340        350        360 
FTVQWNKSPE HIRQAYLDTF KYLPNLLFIW QTGLPNSSNL PSNLLVKPWL PLQDLLGHQK 

       370        380        390        400        410        420 
CRCHVSHGGL NSVIESVYHG VPVVGVPLTS RGYDNLLRIT ARDSGVMVEK SEFSGEILTA 

       430        440        450        460        470        480 
AINEVIENEK YKKEMLIFQD MVIDVPYTEL YHAAFWVEFI ERHQEVPHAR SGADHLNFLQ 

       490        500        510        520        530 
YFLVDVIAFF FFVIFCTLSI IYYTIRTVFR TIRSVVNGVR GVPKIVSRGK KNN 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z36752 Genomic DNA. Translation: CAA85328.2.
PIRT21823.
RefSeqNP_496059.2. NM_063658.6.
UniGeneCel.17672.

3D structure databases

ProteinModelPortalQ20086.
SMRQ20086. Positions 328-433.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6239.F35H8.6.

Protein family/group databases

CAZyGT1. Glycosyltransferase Family 1.

Proteomic databases

PaxDbQ20086.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaF35H8.6; F35H8.6; WBGene00009450.
GeneID174507.
KEGGcel:CELE_F35H8.6.
UCSCF35H8.6. c. elegans.

Organism-specific databases

CTD174507.
WormBaseF35H8.6; CE00984; WBGene00009450; ugt-58.

Phylogenomic databases

eggNOGNOG247080.
GeneTreeENSGT00560000076760.
HOGENOMHOG000016218.
InParanoidQ20086.
KOK00699.
OMAHIVQPRI.
PhylomeDBQ20086.

Family and domain databases

InterProIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERPTHR11926. PTHR11926. 1 hit.
PfamPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio884324.

Entry information

Entry nameUGT58_CAEEL
AccessionPrimary (citable) accession number: Q20086
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 6, 2002
Last modified: June 11, 2014
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase