Q1ZXI6 (PROSC_DICDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Proline synthase co-transcribed bacterial homolog protein

Gene names

Name:	prosc
ORF Names:	DDB_G0278713

Organism

Dictyostelium discoideum (Slime mold)

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the UPF0001 family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from sequence or structural similarity. Source: dictyBase
Molecular function	pyridoxal phosphate binding Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	Proline synthase co-transcribed bacterial homolog protein		PRO_0000328898
Regions
	Compositional bias	122 – 139	18	Asn-rich
Amino acid modifications
	Modified residue	40	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1ZXI6 [UniParc]. Last modified January 19, 2010. Version 2. Checksum: 8B59463EAC93B4B6	FASTA	255	28,985
	10 20 30 40 50 60 MMDENDVKEL ISSYKNIKDR VEIISNKFDR HNVKLVAVSK TKPTEMIRIL YDKGHRHFGE 70 80 90 100 110 120 NYIQELVSKS EELSELNEIK WHFIGSIQSN KSKILTSVKN LYVVETVENK KILDKLAKSL 130 140 150 160 170 180 LNNEENNNNN NNNNNKKLNI MIQVNTSGEE SKSGCKPEEC LDLVKHCLED NNCKNSLNFL 190 200 210 220 230 240 GLMTIGNPNA TPDQPDFKCL VDCKNNISKQ LNIPLDSIEL SMGMSHDFEP AIEFGSTSVR 250 VGSAIFGERD YSNKK

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAFI02000023 Genomic DNA. Translation: EAS66901.2.
RefSeq	XP_001134585.2. XM_001134585.2.
3D structure databases
ProteinModelPortal	Q1ZXI6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1ZXI6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0305032; DDB0305032; DDB_G0278713.
GeneID	8621656.
GenomeReviews	Gene locus prosc in contig CM000152_GR.
KEGG	ddi:DDB_G0278713.
Organism-specific databases
dictyBase	DDB_G0278713. prosc.
Phylogenomic databases
eggNOG	KOG3157.
GeneTree	EPrGT00050000005974.
HOGENOM	HBG289671.
OMA	AVSKTFE.
ProtClustDB	CLSZ2428919.
Family and domain databases
InterPro	IPR001608. Ala_racemase_N. IPR011078. UPF0001. [Graphical view]
PANTHER	PTHR10146. PP_YBL036C. 1 hit.
Pfam	PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PIRSF	PIRSF004848. YBL036c_PLPDEIII. 1 hit.
TIGRFAMs	TIGR00044. TIGR00044. 1 hit.
PROSITE	PS01211. UPF0001. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PROSC_DICDI

Accession

Primary (citable) accession number: Q1ZXI6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	January 19, 2010
Last modified:	December 14, 2011
This is version 35 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)