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Q1ZXG8

- D1060_DICDI

UniProt

Q1ZXG8 - D1060_DICDI

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Protein
Probable tyrosine-protein phosphatase DG1060
Gene
DG1060, DDB_G0281953
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011Phosphocysteine intermediate Reviewed prediction

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable tyrosine-protein phosphatase DG1060 (EC:3.1.3.48)
    Alternative name(s):
    Developmental gene 1060 protein
    Gene namesi
    Name:DG1060
    ORF Names:DDB_G0281953
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 3, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0281953.

    Subcellular locationi

    Cytoplasm Reviewed prediction

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 166166Probable tyrosine-protein phosphatase DG1060
    PRO_0000368208Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi44689.DDB_0232939.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1ZXG8.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG2365.
    InParanoidiQ1ZXG8.
    KOiK18043.
    OMAiKLQRWNL.
    PhylomeDBiQ1ZXG8.

    Family and domain databases

    Gene3Di3.90.190.10. 1 hit.
    InterProiIPR029021. Prot-tyrosine_phosphatase-like.
    IPR020428. Tyr_Pase_dualsp-Pase_euk.
    IPR004861. Tyr_Pase_SIW14-like.
    [Graphical view]
    PfamiPF03162. Y_phosphatase2. 1 hit.
    [Graphical view]
    PRINTSiPR01911. PFDSPHPHTASE.
    SUPFAMiSSF52799. SSF52799. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q1ZXG8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAHHIPPLNF GMVADDLYRS GQPNELNFPF LEKLQLKKII FLAPDDPSQQ    50
    FQNFVEDQDI ELIHLGMDTH QNPWNPISEE IVISALKIIL NPDNYPLHIM 100
    CNLGRHRTGT VVGCLRKLQR WNLTSIFEEY RRFAGSKVKL LNEQFIELFD 150
    TDLVTYNNAP QWLYLS 166
    Length:166
    Mass (Da):19,380
    Last modified:May 2, 2006 - v1
    Checksum:i632F2F84E8D17050
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000044 Genomic DNA. Translation: EAS66873.1.
    AF020278 Genomic DNA. Translation: AAB70846.1.
    RefSeqiXP_001134556.1. XM_001134556.1.

    Genome annotation databases

    EnsemblProtistsiDDB0232939; DDB0232939; DDB_G0281953.
    GeneIDi8623336.
    KEGGiddi:DDB_G0281953.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000044 Genomic DNA. Translation: EAS66873.1 .
    AF020278 Genomic DNA. Translation: AAB70846.1 .
    RefSeqi XP_001134556.1. XM_001134556.1.

    3D structure databases

    ProteinModelPortali Q1ZXG8.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 44689.DDB_0232939.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0232939 ; DDB0232939 ; DDB_G0281953 .
    GeneIDi 8623336.
    KEGGi ddi:DDB_G0281953.

    Organism-specific databases

    dictyBasei DDB_G0281953.

    Phylogenomic databases

    eggNOGi COG2365.
    InParanoidi Q1ZXG8.
    KOi K18043.
    OMAi KLQRWNL.
    PhylomeDBi Q1ZXG8.

    Family and domain databases

    Gene3Di 3.90.190.10. 1 hit.
    InterProi IPR029021. Prot-tyrosine_phosphatase-like.
    IPR020428. Tyr_Pase_dualsp-Pase_euk.
    IPR004861. Tyr_Pase_SIW14-like.
    [Graphical view ]
    Pfami PF03162. Y_phosphatase2. 1 hit.
    [Graphical view ]
    PRINTSi PR01911. PFDSPHPHTASE.
    SUPFAMi SSF52799. SSF52799. 1 hit.
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.
    2. Loomis W.F., Iranfar N.
      Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-46.
      Strain: AX4.

    Entry informationi

    Entry nameiD1060_DICDI
    AccessioniPrimary (citable) accession number: Q1ZXG8
    Secondary accession number(s): O15745
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: May 2, 2006
    Last modified: September 3, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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