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Q1XDM0

- ODPA_PYRYE

UniProt

Q1XDM0 - ODPA_PYRYE

Protein

Pyruvate dehydrogenase E1 component subunit alpha

Gene

pdhA

Organism
Pyropia yezoensis (Red alga) (Porphyra yezoensis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (02 May 2006)
      Previous versions | rss
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    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.By similarity

    Catalytic activityi

    Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

    Cofactori

    Thiamine pyrophosphate.

    GO - Molecular functioni

    1. pyruvate dehydrogenase (acetyl-transferring) activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Pyruvate, Thiamine pyrophosphate

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyruvate dehydrogenase E1 component subunit alpha (EC:1.2.4.1)
    Gene namesi
    Name:pdhA
    Synonyms:odpA
    Encoded oniPlastid; Chloroplast
    OrganismiPyropia yezoensis (Red alga) (Porphyra yezoensis)
    Taxonomic identifieri2788 [NCBI]
    Taxonomic lineageiEukaryotaRhodophytaBangiophyceaeBangialesBangiaceaePyropia

    Subcellular locationi

    GO - Cellular componenti

    1. chloroplast Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chloroplast, Plastid

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 346346Pyruvate dehydrogenase E1 component subunit alphaPRO_0000277253Add
    BLAST

    Interactioni

    Subunit structurei

    Heterodimer of an alpha and a beta chain.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ1XDM0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.40.50.970. 1 hit.
    InterProiIPR001017. DH_E1.
    IPR017597. Pyrv_DH_E1_asu_subgrp-y.
    IPR029061. THDP-binding.
    [Graphical view]
    PfamiPF00676. E1_dh. 1 hit.
    [Graphical view]
    SUPFAMiSSF52518. SSF52518. 1 hit.
    TIGRFAMsiTIGR03182. PDH_E1_alph_y. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q1XDM0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSYPKKVQLP LTNYNSTGLN LNKSNLLVLY EDMLLGRNFE DMCAQMYYKG    50
    KMFGFVHLYN GQEAVSTGVI KLLNPTDYVC STYRDHVHAL SKGVPSKNVM 100
    AELFGKETGC SKGRGGSMHI FSAPHNFLGG FAFIAEGIPV ATGAAFQSIY 150
    RQQVLKETED LRVTACFFGD GTTNNGQFFE CLNMAVLWKL PIIFVVENNQ 200
    WAIGMAHHRS SSIPEIHKKA EAFGLPGIEV DGMDVLAVRQ AAKQAVQRAR 250
    QGDGPTLIEA LTYRFRGHSL ADPDELRSRQ EKEAWVARDP IKKLKKYILD 300
    NEIANIGELN EIQNAVKTEL EQAVKFAISS PEPNMSELKR YLFADN 346
    Length:346
    Mass (Da):38,637
    Last modified:May 2, 2006 - v1
    Checksum:iF5562613F29D9496
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006715 Genomic DNA. Translation: BAE92391.1.
    RefSeqiYP_536948.1. NC_007932.1.

    Genome annotation databases

    GeneIDi3978893.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006715 Genomic DNA. Translation: BAE92391.1 .
    RefSeqi YP_536948.1. NC_007932.1.

    3D structure databases

    ProteinModelPortali Q1XDM0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3978893.

    Family and domain databases

    Gene3Di 3.40.50.970. 1 hit.
    InterProi IPR001017. DH_E1.
    IPR017597. Pyrv_DH_E1_asu_subgrp-y.
    IPR029061. THDP-binding.
    [Graphical view ]
    Pfami PF00676. E1_dh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52518. SSF52518. 1 hit.
    TIGRFAMsi TIGR03182. PDH_E1_alph_y. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequence of Porphyra yezoensis chloroplast."
      Kunimoto M., Morishima K., Yoshikawa M., Fukuda S., Kobayashi T., Kobayashi M., Okazaki T., Ohara I., Nakayama I.
      Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: U-51.

    Entry informationi

    Entry nameiODPA_PYRYE
    AccessioniPrimary (citable) accession number: Q1XDM0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 6, 2007
    Last sequence update: May 2, 2006
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)