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Q1XDM0 (ODPA_PYRYE) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyruvate dehydrogenase E1 component subunit alpha

EC=1.2.4.1
Gene names
Name:pdhA
Synonyms:odpA
Encoded onPlastid; Chloroplast
OrganismPyropia yezoensis (Red alga) (Porphyra yezoensis)
Taxonomic identifier2788 [NCBI]
Taxonomic lineageEukaryotaRhodophytaBangiophyceaeBangialesBangiaceaePyropia

Protein attributes

Sequence length346 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activity

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactor

Thiamine pyrophosphate.

Subunit structure

Heterodimer of an alpha and a beta chain By similarity.

Subcellular location

Plastidchloroplast.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentChloroplast
Plastid
   LigandPyruvate
Thiamine pyrophosphate
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionpyruvate dehydrogenase (acetyl-transferring) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 346346Pyruvate dehydrogenase E1 component subunit alpha
PRO_0000277253

Sequences

Sequence LengthMass (Da)Tools
Q1XDM0 [UniParc].

Last modified May 2, 2006. Version 1.
Checksum: F5562613F29D9496

FASTA34638,637
        10         20         30         40         50         60 
MSYPKKVQLP LTNYNSTGLN LNKSNLLVLY EDMLLGRNFE DMCAQMYYKG KMFGFVHLYN 

        70         80         90        100        110        120 
GQEAVSTGVI KLLNPTDYVC STYRDHVHAL SKGVPSKNVM AELFGKETGC SKGRGGSMHI 

       130        140        150        160        170        180 
FSAPHNFLGG FAFIAEGIPV ATGAAFQSIY RQQVLKETED LRVTACFFGD GTTNNGQFFE 

       190        200        210        220        230        240 
CLNMAVLWKL PIIFVVENNQ WAIGMAHHRS SSIPEIHKKA EAFGLPGIEV DGMDVLAVRQ 

       250        260        270        280        290        300 
AAKQAVQRAR QGDGPTLIEA LTYRFRGHSL ADPDELRSRQ EKEAWVARDP IKKLKKYILD 

       310        320        330        340 
NEIANIGELN EIQNAVKTEL EQAVKFAISS PEPNMSELKR YLFADN 

« Hide

References

[1]"Whole genome sequence of Porphyra yezoensis chloroplast."
Kunimoto M., Morishima K., Yoshikawa M., Fukuda S., Kobayashi T., Kobayashi M., Okazaki T., Ohara I., Nakayama I.
Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: U-51.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006715 Genomic DNA. Translation: BAE92391.1.
RefSeqYP_536948.1. NC_007932.1.

3D structure databases

ProteinModelPortalQ1XDM0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3978893.

Phylogenomic databases

ProtClustDBCHL00149.

Family and domain databases

InterProIPR001017. DH_E1.
IPR017597. Pyrv_DH_E1_asu_subgrp-y.
[Graphical view]
PfamPF00676. E1_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR03182. PDH_E1_alph_y. 1 hit.
ProtoNetSearch...

Entry information

Entry nameODPA_PYRYE
AccessionPrimary (citable) accession number: Q1XDM0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: May 2, 2006
Last modified: October 16, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)