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Q1XDM0

- ODPA_PYRYE

UniProt

Q1XDM0 - ODPA_PYRYE

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Protein

Pyruvate dehydrogenase E1 component subunit alpha

Gene

pdhA

Organism
Pyropia yezoensis (Red alga) (Porphyra yezoensis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).By similarity

Catalytic activityi

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactori

Thiamine pyrophosphate.

GO - Molecular functioni

  1. pyruvate dehydrogenase (acetyl-transferring) activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Pyruvate, Thiamine pyrophosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate dehydrogenase E1 component subunit alpha (EC:1.2.4.1)
Gene namesi
Name:pdhA
Synonyms:odpA
Encoded oniPlastid; Chloroplast
OrganismiPyropia yezoensis (Red alga) (Porphyra yezoensis)
Taxonomic identifieri2788 [NCBI]
Taxonomic lineageiEukaryotaRhodophytaBangiophyceaeBangialesBangiaceaePyropia

Subcellular locationi

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 346346Pyruvate dehydrogenase E1 component subunit alphaPRO_0000277253Add
BLAST

Interactioni

Subunit structurei

Heterodimer of an alpha and a beta chain.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ1XDM0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR017597. Pyrv_DH_E1_asu_subgrp-y.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.
TIGRFAMsiTIGR03182. PDH_E1_alph_y. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1XDM0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSYPKKVQLP LTNYNSTGLN LNKSNLLVLY EDMLLGRNFE DMCAQMYYKG
60 70 80 90 100
KMFGFVHLYN GQEAVSTGVI KLLNPTDYVC STYRDHVHAL SKGVPSKNVM
110 120 130 140 150
AELFGKETGC SKGRGGSMHI FSAPHNFLGG FAFIAEGIPV ATGAAFQSIY
160 170 180 190 200
RQQVLKETED LRVTACFFGD GTTNNGQFFE CLNMAVLWKL PIIFVVENNQ
210 220 230 240 250
WAIGMAHHRS SSIPEIHKKA EAFGLPGIEV DGMDVLAVRQ AAKQAVQRAR
260 270 280 290 300
QGDGPTLIEA LTYRFRGHSL ADPDELRSRQ EKEAWVARDP IKKLKKYILD
310 320 330 340
NEIANIGELN EIQNAVKTEL EQAVKFAISS PEPNMSELKR YLFADN
Length:346
Mass (Da):38,637
Last modified:May 2, 2006 - v1
Checksum:iF5562613F29D9496
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006715 Genomic DNA. Translation: BAE92391.1.
RefSeqiYP_536948.1. NC_007932.1.

Genome annotation databases

GeneIDi3978893.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006715 Genomic DNA. Translation: BAE92391.1 .
RefSeqi YP_536948.1. NC_007932.1.

3D structure databases

ProteinModelPortali Q1XDM0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3978893.

Family and domain databases

Gene3Di 3.40.50.970. 1 hit.
InterProi IPR001017. DH_E1.
IPR017597. Pyrv_DH_E1_asu_subgrp-y.
IPR029061. THDP-binding.
[Graphical view ]
Pfami PF00676. E1_dh. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 1 hit.
TIGRFAMsi TIGR03182. PDH_E1_alph_y. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Whole genome sequence of Porphyra yezoensis chloroplast."
    Kunimoto M., Morishima K., Yoshikawa M., Fukuda S., Kobayashi T., Kobayashi M., Okazaki T., Ohara I., Nakayama I.
    Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: U-51.

Entry informationi

Entry nameiODPA_PYRYE
AccessioniPrimary (citable) accession number: Q1XDM0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: May 2, 2006
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)