Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cell proliferation-inducing protein 23

Gene

PIAS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cell proliferation-inducing protein 23Imported
Submitted name:
Protein inhibitor of activated STAT, 1, isoform CRA_bImported
Gene namesi
Name:PIAS1Imported
ORF Names:hCG_23811Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Expressioni

Gene expression databases

BgeeiENSG00000033800.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000249636.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 3635SAPInterPro annotationAdd
BLAST
Domaini115 – 279165PINITInterPro annotationAdd
BLAST
Domaini311 – 38878SP-RING-typeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2169. Eukaryota.
ENOG410XQ2E. LUCA.
HOVERGENiHBG053598.

Family and domain databases

Gene3Di1.10.720.30. 1 hit.
InterProiIPR027227. PIAS1.
IPR023321. PINIT.
IPR003034. SAP_dom.
IPR004181. Znf_MIZ.
[Graphical view]
PANTHERiPTHR10782:SF11. PTHR10782:SF11. 1 hit.
PfamiPF14324. PINIT. 1 hit.
PF02891. zf-MIZ. 1 hit.
[Graphical view]
SMARTiSM00513. SAP. 1 hit.
[Graphical view]
PROSITEiPS51466. PINIT. 1 hit.
PS50800. SAP. 1 hit.
PS51044. ZF_SP_RING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1XBU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVMSLRVSEL QVLLGYAGRN KHGRKHELLT KALHLLKAGC SPAVQMKIKE
60 70 80 90 100
LYRRRFPQKI MTPADLSIPN VHSSPMPATL SPSTIPQLTY DGHPASSPLL
110 120 130 140 150
PVSLLGPKHE LELPHLTSAL HPVHPDIKLQ KLPFYDLLDE LIKPTSLASD
160 170 180 190 200
NSQRFRETCF AFALTPQQVQ QISSSMDISG TKCDFTVQVQ LRFCLSETSC
210 220 230 240 250
PQEDHFPPNL CVKVNTKPCS LPGYLPPTKN GVEPKRPSRP INITSLVRLS
260 270 280 290 300
TTVPNTIVVS WTAEIGRNYS MAVYLVKQLS STVLLQRLRA KGIRNPDHSR
310 320 330 340 350
ALIKEKLTAD PDSEIATTSL RVSLLCPLGK MRLTIPCRAL TCSHLQCFDA
360 370 380 390 400
TLYIQMNEKK PTWVCPVCDK KAPYEHLIID GLFMEILKYC TDCDEIQFKE
410 420 430 440 450
DGTWAPMRSK KEVQEVSASY NGVDGCLSST LEHQVASHHQ SSNKNKKVEV
460 470 480 490 500
IDLTIDSSSD EEEEEPSAKR TCPSLSPTSP LNNKGILSLP HQASPVSRTP
510 520 530 540 550
SLPAVDTSYI NTSLIQDYRH PFHMTPMPYD LQGLDFFPFL SGDNQHYNTS
560 570 580 590 600
LLAAAAAAVS DDQDLLHSSR FFPYTSSQMF LDQLSAGGST SLPTTNGSSS
610 620 630 640
GSNSSLVSSN SLRESHSHTV TNRSSTDTAS IFGIIPDIIS LD
Length:642
Mass (Da):70,862
Last modified:May 2, 2006 - v1
Checksum:i62B7AA377E03D427
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY826819 mRNA. Translation: AAX18639.1.
CH471082 Genomic DNA. Translation: EAW77805.1.
UniGeneiHs.162458.
Hs.694796.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY826819 mRNA. Translation: AAX18639.1.
CH471082 Genomic DNA. Translation: EAW77805.1.
UniGeneiHs.162458.
Hs.694796.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000249636.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

CTDi8554.

Phylogenomic databases

eggNOGiKOG2169. Eukaryota.
ENOG410XQ2E. LUCA.
HOVERGENiHBG053598.

Miscellaneous databases

ChiTaRSiPIAS1. human.
GenomeRNAii8554.

Gene expression databases

BgeeiENSG00000033800.

Family and domain databases

Gene3Di1.10.720.30. 1 hit.
InterProiIPR027227. PIAS1.
IPR023321. PINIT.
IPR003034. SAP_dom.
IPR004181. Znf_MIZ.
[Graphical view]
PANTHERiPTHR10782:SF11. PTHR10782:SF11. 1 hit.
PfamiPF14324. PINIT. 1 hit.
PF02891. zf-MIZ. 1 hit.
[Graphical view]
SMARTiSM00513. SAP. 1 hit.
[Graphical view]
PROSITEiPS51466. PINIT. 1 hit.
PS50800. SAP. 1 hit.
PS51044. ZF_SP_RING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ1XBU8_HUMAN
AccessioniPrimary (citable) accession number: Q1XBU8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 2, 2006
Last sequence update: May 2, 2006
Last modified: September 7, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.