ID   MSRB_LACS1              Reviewed;         144 AA.
AC   Q1WVT3;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Peptide methionine sulfoxide reductase msrB;
DE            EC=1.8.4.12;
DE   AltName: Full=Peptide-methionine (R)-S-oxide reductase;
GN   Name=msrB; OrderedLocusNames=LSL_0029;
OS   Lactobacillus salivarius subsp. salivarius (strain UCC118).
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=362948;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16617113; DOI=10.1073/pnas.0511060103;
RA   Claesson M.J., Li Y., Leahy S., Canchaya C., van Pijkeren J.P.,
RA   Cerdeno-Tarraga A.M., Parkhill J., Flynn S., O'Sullivan G.C.,
RA   Collins J.K., Higgins D., Shanahan F., Fitzgerald G.F.,
RA   van Sinderen D., O'Toole P.W.;
RT   "Multireplicon genome architecture of Lactobacillus salivarius.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:6718-6723(2006).
CC   -!- CATALYTIC ACTIVITY: Peptide-L-methionine + thioredoxin disulfide +
CC       H(2)O = peptide-L-methionine (R)-S-oxide + thioredoxin.
CC   -!- SIMILARITY: Belongs to the msrB Met sulfoxide reductase family.
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DR   EMBL; CP000233; ABD98852.1; -; Genomic_DNA.
DR   RefSeq; YP_534935.1; -.
DR   GeneID; 3978236; -.
DR   GenomeReviews; CP000233_GR; LSL_0029.
DR   KEGG; lsl:LSL_0029; -.
DR   HOGENOM; Q1WVT3; -.
DR   OMA; Q1WVT3; KYESGCG.
DR   BioCyc; LSAL362948:LSL_0029-MON; -.
DR   GO; GO:0033743; F:peptide-methionine (R)-S-oxide reductase ac...; IEA:EC.
DR   GO; GO:0008113; F:peptide-methionine-(S)-S-oxide reductase ac...; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_01400; -; 1.
DR   InterPro; IPR002579; Methionine_sulphoxide_MsrB.
DR   Gene3D; G3DSA:2.170.150.20; MsrB; 1.
DR   Pfam; PF01641; SelR; 1.
DR   ProDom; PD004057; DUF25; 1.
DR   TIGRFAMs; TIGR00357; MsrB; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Oxidoreductase.
FT   CHAIN         1    144       Peptide methionine sulfoxide reductase
FT                                msrB.
FT                                /FTId=PRO_1000068276.
FT   ACT_SITE    117    117       Nucleophile (By similarity).
SQ   SEQUENCE   144 AA;  16452 MW;  2EDC7614E42CD591 CRC64;
     MKETKEELRQ RIGEEAYQVT QNAATERAFT GKYDEFFEDG IYVDVVSGEP LFSSKDKYNS
     GCGWPAFTQP INNRMVTNHE DNSFGMHRVE VRSRQAQSHL GHVFNDGPQD RGGLRYCINS
     AALQFIPVAE LDEKGYGEYK KLFD
//