Q1WUJ1 (Q1WUJ1_LACS1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Exodeoxyribonuclease 7 small subunit HAMAP-Rule MF_00337
EC=3.1.11.6 HAMAP-Rule MF_00337

Alternative name(s):
Exodeoxyribonuclease VII small subunit HAMAP-Rule MF_00337

Gene names

Name:	xseB HAMAP-Rule MF_00337 EMBL ABD99344.1
Ordered Locus Names:	LSL_0535 EMBL ABD99344.1

Organism

Lactobacillus salivarius (strain UCC118) [Complete proteome] [HAMAP] EMBL ABD99344.1

Taxonomic identifier

362948 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus salivarius

Protein attributes

Sequence length	75 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity. HAMAP-Rule MF_00337
Catalytic activity	Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_00337
Subunit structure	Heterooligomer composed of large and small subunits By similarity. HAMAP-Rule MF_00337
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00337.
Sequence similarities	Belongs to the XseB family. HAMAP-Rule MF_00337

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP-Rule MF_00337
Molecular function	Exonuclease HAMAP-Rule MF_00337 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA catabolic process Inferred from electronic annotation. Source: HAMAP nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell exodeoxyribonuclease VII complex Inferred from electronic annotation. Source: InterPro
Molecular_function	exodeoxyribonuclease VII activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1WUJ1 [UniParc]. Last modified May 2, 2006. Version 1. Checksum: F38FC14B9206E8A1	FASTA	75	8,743
	10 20 30 40 50 60 MAEKVTFEQD MKNLEEIVKR LEQGDIPLEE AIEKFKQGMD LSKKLQNTLL QAEETLTKVI 70 DDNGDEQLFE KENED

References

[1]

"Multireplicon genome architecture of Lactobacillus salivarius." Claesson M.J., Li Y., Leahy S., Canchaya C., van Pijkeren J.P., Cerdeno-Tarraga A.M., Parkhill J., Flynn S., O'Sullivan G.C., Collins J.K., Higgins D., Shanahan F., Fitzgerald G.F., van Sinderen D., O'Toole P.W. Proc. Natl. Acad. Sci. U.S.A. 103:6718-6723(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: UCC118 EMBL ABD99344.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000233 Genomic DNA. Translation: ABD99344.1.
RefSeq	YP_535427.1. NC_007929.1.
3D structure databases
ProteinModelPortal	Q1WUJ1.
ModBase	Search...
Protein-protein interaction databases
STRING	362948.LSL_0535.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABD99344; ABD99344; LSL_0535.
GeneID	3976493.
KEGG	lsl:LSL_0535.
PATRIC	22277973. VBILacSal43464_0613.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1722.
HOGENOM	HOG000228798.
KO	K03602.
OMA	LCHDKLQ.
Enzyme and pathway databases
BioCyc	LSAL362948:GJDJ-604-MONOMER.
Family and domain databases
Gene3D	1.10.287.1040. 1 hit.
HAMAP	MF_00337. Exonuc_7_S.
InterPro	IPR003761. Exonuc_VII_S. [Graphical view]
Pfam	PF02609. Exonuc_VII_S. 1 hit. [Graphical view]
PIRSF	PIRSF006488. Exonuc_VII_S. 1 hit.
ProDom	PD028235. Exonuc_VII_S. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF116842. SSF116842. 1 hit.
TIGRFAMs	TIGR01280. xseB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1WUJ1_LACS1

Accession

Primary (citable) accession number: Q1WUJ1

Entry history

Integrated into UniProtKB/TrEMBL:	May 2, 2006
Last sequence update:	May 2, 2006
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)