ID   Q1WSN3_LIGS1            Unreviewed;       607 AA.
AC   Q1WSN3;
DT   02-MAY-2006, integrated into UniProtKB/TrEMBL.
DT   02-MAY-2006, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Alpha-amylase {ECO:0000313|EMBL:ABE00096.1};
DE            EC=3.2.1.1 {ECO:0000313|EMBL:ABE00096.1};
GN   Name=amyA {ECO:0000313|EMBL:ABE00096.1};
GN   OrderedLocusNames=LSL_1289 {ECO:0000313|EMBL:ABE00096.1};
OS   Ligilactobacillus salivarius (strain UCC118) (Lactobacillus salivarius).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Ligilactobacillus.
OX   NCBI_TaxID=362948 {ECO:0000313|EMBL:ABE00096.1, ECO:0000313|Proteomes:UP000006559};
RN   [1] {ECO:0000313|EMBL:ABE00096.1, ECO:0000313|Proteomes:UP000006559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCC118 {ECO:0000313|EMBL:ABE00096.1,
RC   ECO:0000313|Proteomes:UP000006559};
RX   PubMed=16617113; DOI=10.1073/pnas.0511060103;
RA   Claesson M.J., Li Y., Leahy S., Canchaya C., van Pijkeren J.P.,
RA   Cerdeno-Tarraga A.M., Parkhill J., Flynn S., O'Sullivan G.C., Collins J.K.,
RA   Higgins D., Shanahan F., Fitzgerald G.F., van Sinderen D., O'Toole P.W.;
RT   "Multireplicon genome architecture of Lactobacillus salivarius.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:6718-6723(2006).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC       {ECO:0000256|ARBA:ARBA00008061}.
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DR   EMBL; CP000233; ABE00096.1; -; Genomic_DNA.
DR   RefSeq; WP_011476255.1; NC_007929.1.
DR   RefSeq; YP_536179.1; NC_007929.1.
DR   AlphaFoldDB; Q1WSN3; -.
DR   SMR; Q1WSN3; -.
DR   STRING; 362948.LSL_1289; -.
DR   CAZy; GH13; Glycoside Hydrolase Family 13.
DR   KEGG; lsl:LSL_1289; -.
DR   PATRIC; fig|362948.14.peg.1363; -.
DR   HOGENOM; CLU_006462_6_4_9; -.
DR   OrthoDB; 9805159at2; -.
DR   Proteomes; UP000006559; Chromosome.
DR   GO; GO:0004556; F:alpha-amylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd11338; AmyAc_CMD; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR045857; O16G_dom_2.
DR   PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR10357:SF210; MALTODEXTRIN GLUCOSIDASE; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000313|EMBL:ABE00096.1};
KW   Hydrolase {ECO:0000313|EMBL:ABE00096.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006559}.
FT   DOMAIN          137..526
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
SQ   SEQUENCE   607 AA;  70867 MW;  DD1CB722C0B3A6BD CRC64;
     MAHILYNAWD SLYKEPFGAV KIDHEVVWRL QVFPDENEEI HYVNLILTKD GEEDVPYALE
     NLNHDGLYQV KLQIGTAGLY FYHFEIETSH GRSYLEKRQG GMAQQVSSQS DLLRFQLTCF
     DEEVPSPKWY RQGVVYQIFP DRFANGLPNG EVQGRKPNSF IYGTTADKPY YIRDKNNEIV
     RWDFYGGNLK GILKKLPYLE ELGVTTIYLN PIFLSRSNHH YDTADFLKID PMIGNEDDLK
     ELITEMHKKN MHLILDGVFN HVGKESIYFN ASGSYGKNVG AAQSKESPYY SWFDFIHYPD
     DYKSWWGIKD LPVIDKDNPE YQKFIYGDSN RSVLSKWNNF GIDGWRLDVA DELPMNFLRG
     IRKNLDSHHK QVMIGEVWED ASNKIAYDER RQYTVGDNLT GVMGYPTRIF VMDLLESVKS
     SQDIKKYCNE YLQLQENYPR DFWLNTLNNI GTHDTQRIKT VLHNDDNKVI QAFRILFNLP
     GVPCIYYGDE VGVEGDADPD NRRFFPWGQE KNSRIIQEVK QLVDKRKKNI LLQEGRLGFV
     IARGSHCPAL AIVRYDDQGN SVYNWLNLTQ YKQIISPENG EYLCLPQNIQ QKFQHELTLD
     SWEYKVI
//