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Protein

Glycogen synthase

Gene

glgA

Organism
Lactobacillus salivarius (strain UCC118)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciLSAL362948:GJDJ-1379-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:LSL_1291
OrganismiLactobacillus salivarius (strain UCC118)
Taxonomic identifieri362948 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000006559 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 476476Glycogen synthasePRO_1000014368Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi362948.LSL_1291.

Structurei

3D structure databases

ProteinModelPortaliQ1WSN1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1WSN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLLFAGSEC APFFKTGGLG DVMGALPKTI AKTTDNDVRV VLPFFTGMAE
60 70 80 90 100
EYKSQLSFVT SFYVKVGWRD QYCGVLKLEM DNVTYYFIDN LYYFDRPGLY
110 120 130 140 150
GYYDEGERWA FFQQAIIEML EKIGFIPDIL HVNDYHTAFI PFLLKEKYGW
160 170 180 190 200
INAYQSIKTV LTIHNLQFQG EYGREVLGEL FNLDASYYDD GTVRFDTAVN
210 220 230 240 250
FMKTGILYAD KVNTVSPTYA SEIQTEAFGQ GLDEILRMHN WKLRGILNGI
260 270 280 290 300
DYERNNPATD KNLVANYSAK KLKGKVKDKL ALQKEFGLPQ RKDVPVIAMV
310 320 330 340 350
SRLTAQKGFQ LVVSEMQNLV QFDVQVIVLG TGDANFEHDF RYFADTYPDK
360 370 380 390 400
VGAAITFDVG LAQRIYAGAD MFLMPSAFEP CGLSQMISMR YGTLPIVHQI
410 420 430 440 450
GGLQDSVQPF NPVTGEGTGF GFHDFSGFYM MQEIQEALRL YAESVAWTKV
460 470
VKQAMSQDFS WETASQEYLN MYNELV
Length:476
Mass (Da):54,096
Last modified:May 2, 2006 - v1
Checksum:i3926E6BDAE8F3185
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000233 Genomic DNA. Translation: ABE00098.1.
RefSeqiWP_011476257.1. NC_007929.1.
YP_536181.1. NC_007929.1.

Genome annotation databases

EnsemblBacteriaiABE00098; ABE00098; LSL_1291.
GeneIDi3976543.
KEGGilsl:LSL_1291.
PATRICi22279505. VBILacSal43464_1365.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000233 Genomic DNA. Translation: ABE00098.1.
RefSeqiWP_011476257.1. NC_007929.1.
YP_536181.1. NC_007929.1.

3D structure databases

ProteinModelPortaliQ1WSN1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi362948.LSL_1291.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE00098; ABE00098; LSL_1291.
GeneIDi3976543.
KEGGilsl:LSL_1291.
PATRICi22279505. VBILacSal43464_1365.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciLSAL362948:GJDJ-1379-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UCC118.

Entry informationi

Entry nameiGLGA_LACS1
AccessioniPrimary (citable) accession number: Q1WSN1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 2, 2006
Last modified: April 29, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.