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Protein

Protein PB1-F2

Gene

PB1

Organism
Influenza A virus (strain A/USSR/90/1977 H1N1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May play an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.UniRule annotation

Miscellaneous

Is not encoded in all strains, and seems to be dispensable for replication.

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PB1-F2UniRule annotation
Gene namesi
Name:PB1UniRule annotation
OrganismiInfluenza A virus (strain A/USSR/90/1977 H1N1)
Taxonomic identifieri381516 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A
Virus hostiAves [TaxID: 8782]
Homo sapiens (Human) [TaxID: 9606]
Sus scrofa (Pig) [TaxID: 9823]
Proteomesi
  • UP000007793 Componenti: Genome
  • UP000121508 Componenti: Genome

Subcellular locationi

  • Host nucleus UniRule annotation
  • Host cytoplasmhost cytosol UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm, Host nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002787271 – 57Protein PB1-F2Add BLAST57

Family & Domainsi

Sequence similaritiesi

Belongs to the influenza viruses PB1-F2 family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG090001GF.

Family and domain databases

HAMAPiMF_04064. INFV_PB1F2. 1 hit.
InterProiView protein in InterPro
IPR021045. Flu_proapoptotic_PB1-F2.
PfamiView protein in Pfam
PF11986. PB1-F2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1WP00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQEQGTPWI QSTGHISTQK GEDGQKTPKL EHRNSTRLMG HYQKTMNQVV

MPKQIVY
Length:57
Mass (Da):6,540
Last modified:May 2, 2006 - v1
Checksum:iF640088800E69BA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CY010378 Genomic RNA. Translation: ABD95359.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CY010378 Genomic RNA. Translation: ABD95359.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

OrthoDBiVOG090001GF.

Family and domain databases

HAMAPiMF_04064. INFV_PB1F2. 1 hit.
InterProiView protein in InterPro
IPR021045. Flu_proapoptotic_PB1-F2.
PfamiView protein in Pfam
PF11986. PB1-F2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPB1F2_I77AB
AccessioniPrimary (citable) accession number: Q1WP00
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: May 2, 2006
Last modified: June 7, 2017
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.