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Protein
Submitted name:

Liver receptor-like protein 1 variant 2

Gene

Nr5a2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorUniRule annotationImported

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Liver receptor-like protein 1 variant 2Imported
Submitted name:
Nuclear receptor subfamily 5 group A member 2Imported
Gene namesi
Name:Nr5a2Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1346834. Nr5a2.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027649.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini43 – 11876Nuclear receptor DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation
Contains nuclear receptor DNA-binding domain.SAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4218. Eukaryota.
ENOG410YWC2. LUCA.
GeneTreeiENSGT00760000118887.
HOVERGENiHBG106677.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR016355. NR5_fam.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PANTHERiPTHR24086. PTHR24086. 1 hit.
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PIRSFiPIRSF002530. Nuc_orph_FTZ-F1. 1 hit.
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 2 hits.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1WLP7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPKVETEAP GLVRSHGEQG QMPENMQVSQ FKMVNYSYDE DLEELCPVCG
60 70 80 90 100
DKVSGYHYGL LTCESCKGFF KRTVQNQKRY TCIENQNCQI DKTQRKRCPY
110 120 130 140 150
CRFKKCIDVG MKLEAVRADR MRGGRNKFGP MYKRDRALKQ QKKALIRANG
160 170 180 190 200
LKLEAMSQVI QAMPSDLTSA IQNIHSASKG LPLSHVALPP TDYDRSPFVT
210 220 230 240 250
SPISMTMPPH SSLHGYQPYG HFPSRAIKSE YPDPYSSSPE SMMGYSYMDG
260 270 280 290 300
YQTNSPASIP HLILELLKCE PDEPQVQAKI MAYLQQEQSN RNRQEKLSAF
310 320 330 340 350
GLLCKMADQT LFSIVEWARS SIFFRELKVD DQMKLLQNCW SELLILDHIY
360 370 380 390 400
RQVAHGKEGT IFLVTGEHVD YSTIISHTEV AFNNLLSLAQ ELVVRLRSLQ
410 420 430 440 450
FDQREFVCLK FLVLFSSDVK NLENLQLVEG VQEQVNAALL DYTVCNYPQQ
460 470 480 490
TEKFGQLLLR LPEIRAISKQ AEDYLYYKHV NGDVPYNNLL IEMLHAKRA
Length:499
Mass (Da):57,176
Last modified:May 2, 2006 - v1
Checksum:i889F76EF792B2307
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120182 Genomic DNA. No translation available.
AC124814 Genomic DNA. No translation available.
DQ133942 mRNA. Translation: AAZ99450.1.
RefSeqiNP_001153241.1. NM_001159769.2.
XP_006529685.1. XM_006529622.2.
UniGeneiMm.16794.

Genome annotation databases

EnsembliENSMUST00000168126; ENSMUSP00000129071; ENSMUSG00000026398.
ENSMUST00000192929; ENSMUSP00000141495; ENSMUSG00000026398.
GeneIDi26424.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120182 Genomic DNA. No translation available.
AC124814 Genomic DNA. No translation available.
DQ133942 mRNA. Translation: AAZ99450.1.
RefSeqiNP_001153241.1. NM_001159769.2.
XP_006529685.1. XM_006529622.2.
UniGeneiMm.16794.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027649.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000168126; ENSMUSP00000129071; ENSMUSG00000026398.
ENSMUST00000192929; ENSMUSP00000141495; ENSMUSG00000026398.
GeneIDi26424.

Organism-specific databases

CTDi2494.
MGIiMGI:1346834. Nr5a2.

Phylogenomic databases

eggNOGiKOG4218. Eukaryota.
ENOG410YWC2. LUCA.
GeneTreeiENSGT00760000118887.
HOVERGENiHBG106677.

Miscellaneous databases

NextBioi304453.
SOURCEiSearch...

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR016355. NR5_fam.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PANTHERiPTHR24086. PTHR24086. 1 hit.
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PIRSFiPIRSF002530. Nuc_orph_FTZ-F1. 1 hit.
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 2 hits.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Gao D.-M., Wang L.-F., Liu J., Kong Y.-Y., Wang Y., Xie Y.-H.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
  2. "Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter."
    Gao D.M., Wang L.F., Liu J., Kong Y.Y., Wang Y., Xie Y.H.
    FEBS Lett. 580:1702-1708(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (DEC-2014) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ1WLP7_MOUSE
AccessioniPrimary (citable) accession number: Q1WLP7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 2, 2006
Last sequence update: May 2, 2006
Last modified: May 11, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.