Q1W6G9 (Q1W6G9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hemoglobin zeta subunit EMBL ABD95908.1

Gene names

Name:

HBZ EMBL ABD95908.1

Organism

Homo sapiens (Human) EMBL ABD95908.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	142 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the globin family. RuleBase RU000356

Ontologies

Keywords
Biological process	Oxygen transport RuleBase RU000356 SAAS SAAS002338 Transport
Ligand	Heme RuleBase RU000356 SAAS SAAS002338 Iron Metal-binding
Gene Ontology (GO)
Cellular_component	hemoglobin complex Inferred from electronic annotation. Source: InterPro
Molecular_function	heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro oxygen binding Inferred from electronic annotation. Source: InterPro oxygen transporter activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1W6G9 [UniParc]. Last modified May 2, 2006. Version 1. Checksum: 162A9B97021960E3	FASTA	142	15,621
	10 20 30 40 50 60 MSLTKTERTI IVSMWAKIST QADTIGTETL ERPFLSHPQT KTYFPHFDLH PGSAQLRAHG 70 80 90 100 110 120 SKVVAAVGDA VKSIDDIGGA LSKLSELHAY ILRVDPVNFK LLSHCLLVTL AARFPADFTA 130 140 EAHAAWDKFL SVVSSVLTEK YR

References

[1]	Cheng J.-F., Hamilton M., Peng Y., Hosseini R., Peng Z., Malinov I., Hughes J.R., Gray N.E., Higgs D.R., Rubin E.M. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"A remote gain of function regulatory SNP illustrating a novel mechanism for human genetic disease." De Gobbi M., Viprakasit V., Hughes J.R., Fisher C., Buckle V.J., Ayyub H., Gibbons R.J., Vernimmen D., Yoshinaga Y., de Jong P., Chen J.-F., Rubin E.M., Wood W.G., Bowden D., Higgs D.R. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ431198 Genomic DNA. Translation: ABD95908.1.
IPI	IPI00217473.
UniGene	Hs.585357.
3D structure databases
ProteinModelPortal	Q1W6G9.
SMR	Q1W6G9. Positions 2-142.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1W6G9.
Proteomic databases
PRIDE	Q1W6G9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG009709.
Gene expression databases
ArrayExpress	Q1W6G9.
Family and domain databases
Gene3D	1.10.490.10. 1 hit.
InterPro	IPR000971. Globin. IPR009050. Globin-like. IPR012292. Globin_dom. IPR002338. Haemoglobin_a. IPR002340. Haemoglobin_zeta. [Graphical view]
Pfam	PF00042. Globin. 1 hit. [Graphical view]
PRINTS	PR00612. ALPHAHAEM. PR00816. ZETAHAEM.
SUPFAM	SSF46458. Globin_like. 1 hit.
PROSITE	PS01033. GLOBIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1W6G9_HUMAN

Accession

Primary (citable) accession number: Q1W6G9

Entry history

Integrated into UniProtKB/TrEMBL:	May 2, 2006
Last sequence update:	May 2, 2006
Last modified:	March 6, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.