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Q1W376

- PMM_SOYBN

UniProt

Q1W376 - PMM_SOYBN

Protein

Phosphomannomutase

Gene
N/A
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (02 May 2006)
      Previous versions | rss
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    Functioni

    Involved in ascorbic acid biosynthesis and in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.By similarity

    Catalytic activityi

    Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei13 – 131NucleophileBy similarity
    Active sitei15 – 151Proton donor/acceptorSequence Analysis
    Binding sitei22 – 221SubstrateBy similarity
    Binding sitei124 – 1241SubstrateBy similarity
    Binding sitei135 – 1351SubstrateBy similarity
    Binding sitei142 – 1421SubstrateBy similarity
    Binding sitei180 – 1801SubstrateBy similarity
    Binding sitei182 – 1821SubstrateBy similarity

    GO - Molecular functioni

    1. phosphomannomutase activity Source: UniProtKB-EC

    GO - Biological processi

    1. GDP-mannose biosynthetic process Source: UniProtKB-UniPathway
    2. L-ascorbic acid biosynthetic process Source: EnsemblPlants/Gramene
    3. mannose biosynthetic process Source: InterPro
    4. response to salt stress Source: EnsemblPlants/Gramene

    Keywords - Molecular functioni

    Isomerase

    Enzyme and pathway databases

    UniPathwayiUPA00126; UER00424.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphomannomutase (EC:5.4.2.8)
    Alternative name(s):
    GmPMM
    OrganismiGlycine max (Soybean) (Glycine hispida)
    Taxonomic identifieri3847 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
    ProteomesiUP000008827: Chromosome 18

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytosol Source: EnsemblPlants/Gramene

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 247247PhosphomannomutasePRO_0000326495Add
    BLAST

    Proteomic databases

    PRIDEiQ1W376.

    Expressioni

    Gene expression databases

    GenevestigatoriQ1W376.

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ1W376.
    SMRiQ1W376. Positions 6-244.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the eukaryotic PMM family.Curated

    Phylogenomic databases

    KOiK17497.
    OMAiTYCLQHV.

    Family and domain databases

    Gene3Di3.40.50.1000. 2 hits.
    InterProiIPR023214. HAD-like_dom.
    IPR006379. HAD-SF_hydro_IIB.
    IPR005002. PMM.
    [Graphical view]
    PANTHERiPTHR10466. PTHR10466. 1 hit.
    PfamiPF03332. PMM. 1 hit.
    [Graphical view]
    SUPFAMiSSF56784. SSF56784. 1 hit.
    TIGRFAMsiTIGR01484. HAD-SF-IIB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q1W376-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAARRPGLIA LFDVDGTLTA PRKVVTPEML TFMQELRKVV TVGVVGGSDL    50
    IKISEQLGST VTNDYDYVFS ENGLVAHKEG KLIGTQSLKS FLGEEKLKEF 100
    INFTLHYIAD LDIPIKRGTF IEFRSGMLNV SPIGRNCSQE ERDEFEKYDK 150
    VHNIRPKMVS VLREKFAHLN LTFSIGGQIS FDVFPQGWDK TYCLRYLDGF 200
    NEIHFFGDKT YKGGNDHEIY ESERTVGHTV TSPDDTVKQC KSLFLEN 247
    Length:247
    Mass (Da):28,019
    Last modified:May 2, 2006 - v1
    Checksum:i7FF516DFA51220A1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ442994 mRNA. Translation: ABD97873.1.
    RefSeqiNP_001237668.1. NM_001250739.1.
    XP_006601866.1. XM_006601803.1.
    UniGeneiGma.3992.

    Genome annotation databases

    EnsemblPlantsiGLYMA18G46390.1; GLYMA18G46390.1; GLYMA18G46390.
    GeneIDi732605.
    KEGGigmx:732605.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ442994 mRNA. Translation: ABD97873.1 .
    RefSeqi NP_001237668.1. NM_001250739.1.
    XP_006601866.1. XM_006601803.1.
    UniGenei Gma.3992.

    3D structure databases

    ProteinModelPortali Q1W376.
    SMRi Q1W376. Positions 6-244.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q1W376.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi GLYMA18G46390.1 ; GLYMA18G46390.1 ; GLYMA18G46390 .
    GeneIDi 732605.
    KEGGi gmx:732605.

    Phylogenomic databases

    KOi K17497.
    OMAi TYCLQHV.

    Enzyme and pathway databases

    UniPathwayi UPA00126 ; UER00424 .

    Gene expression databases

    Genevestigatori Q1W376.

    Family and domain databases

    Gene3Di 3.40.50.1000. 2 hits.
    InterProi IPR023214. HAD-like_dom.
    IPR006379. HAD-SF_hydro_IIB.
    IPR005002. PMM.
    [Graphical view ]
    PANTHERi PTHR10466. PTHR10466. 1 hit.
    Pfami PF03332. PMM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56784. SSF56784. 1 hit.
    TIGRFAMsi TIGR01484. HAD-SF-IIB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Molecular and functional analysis of phosphomannomutase (PMM) from higher plants and genetic evidence for the involvement of PMM in ascorbic acid biosynthesis in Arabidopsis and Nicotiana benthamiana."
      Qian W., Yu C., Qin H., Liu X., Zhang A., Johansen I.E., Wang D.
      Plant J. 49:399-413(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiPMM_SOYBN
    AccessioniPrimary (citable) accession number: Q1W376
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: May 2, 2006
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3