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Protein

Phosphomannomutase

Gene
N/A
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in ascorbic acid biosynthesis and in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.By similarity

Catalytic activityi

Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

Pathwayi: GDP-alpha-D-mannose biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes alpha-D-mannose 1-phosphate from D-fructose 6-phosphate.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphomannomutase (GLYMA_18G229800), Phosphomannomutase, Phosphomannomutase, Phosphomannomutase (100819768)
This subpathway is part of the pathway GDP-alpha-D-mannose biosynthesis, which is itself part of Nucleotide-sugar biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes alpha-D-mannose 1-phosphate from D-fructose 6-phosphate, the pathway GDP-alpha-D-mannose biosynthesis and in Nucleotide-sugar biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei13NucleophileBy similarity1
Active sitei15Proton donor/acceptorSequence analysis1
Binding sitei22SubstrateBy similarity1
Binding sitei124SubstrateBy similarity1
Binding sitei135SubstrateBy similarity1
Binding sitei142SubstrateBy similarity1
Binding sitei180SubstrateBy similarity1
Binding sitei182SubstrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase

Enzyme and pathway databases

UniPathwayiUPA00126; UER00424

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphomannomutase (EC:5.4.2.8)
Alternative name(s):
GmPMM
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
Proteomesi
  • UP000008827 Componenti: Chromosome 18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003264951 – 247PhosphomannomutaseAdd BLAST247

Proteomic databases

PRIDEiQ1W376

Expressioni

Gene expression databases

GenevisibleiQ1W376 GM

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi3847.GLYMA18G46390.1

Structurei

3D structure databases

ProteinModelPortaliQ1W376
SMRiQ1W376
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic PMM family.Curated

Phylogenomic databases

eggNOGiKOG3189 Eukaryota
COG0561 LUCA
InParanoidiQ1W376
KOiK17497
OMAiTYCLQHL
OrthoDBiEOG09370QAB

Family and domain databases

CDDicd02585 HAD_PMM, 1 hit
Gene3Di3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR006379 HAD-SF_hydro_IIB
IPR023214 HAD_sf
IPR005002 PMM
PANTHERiPTHR10466 PTHR10466, 1 hit
PfamiView protein in Pfam
PF03332 PMM, 1 hit
SFLDiSFLDG01143 C2.B.3:_Phosphomannomutase_Lik, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01484 HAD-SF-IIB, 1 hit

Sequencei

Sequence statusi: Complete.

Q1W376-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARRPGLIA LFDVDGTLTA PRKVVTPEML TFMQELRKVV TVGVVGGSDL
60 70 80 90 100
IKISEQLGST VTNDYDYVFS ENGLVAHKEG KLIGTQSLKS FLGEEKLKEF
110 120 130 140 150
INFTLHYIAD LDIPIKRGTF IEFRSGMLNV SPIGRNCSQE ERDEFEKYDK
160 170 180 190 200
VHNIRPKMVS VLREKFAHLN LTFSIGGQIS FDVFPQGWDK TYCLRYLDGF
210 220 230 240
NEIHFFGDKT YKGGNDHEIY ESERTVGHTV TSPDDTVKQC KSLFLEN
Length:247
Mass (Da):28,019
Last modified:May 2, 2006 - v1
Checksum:i7FF516DFA51220A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ442994 mRNA Translation: ABD97873.1
RefSeqiNP_001237668.1, NM_001250739.1
XP_006601866.1, XM_006601803.2
UniGeneiGma.3992

Genome annotation databases

EnsemblPlantsiKRH00697; KRH00697; GLYMA_18G229800
GeneIDi732605
GrameneiKRH00697; KRH00697; GLYMA_18G229800
KEGGigmx:732605

Similar proteinsi

Entry informationi

Entry nameiPMM_SOYBN
AccessioniPrimary (citable) accession number: Q1W376
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 2, 2006
Last modified: April 25, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health