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Q1RS89 (LFTR_VIBVU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Leucyl/phenylalanyl-tRNA--protein transferase

EC=2.3.2.6
Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase
Gene names
Name:aat
Ordered Locus Names:VV1_3222
OrganismVibrio vulnificus (strain CMCP6) [Complete proteome] [HAMAP]
Taxonomic identifier216895 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity. HAMAP-Rule MF_00688

Catalytic activity

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein]. HAMAP-Rule MF_00688

L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein]. HAMAP-Rule MF_00688

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00688.

Sequence similarities

Belongs to the L/F-transferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionleucyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 237237Leucyl/phenylalanyl-tRNA--protein transferase HAMAP-Rule MF_00688
PRO_0000289976

Sequences

Sequence LengthMass (Da)Tools
Q1RS89 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 15FF256E64595096

FASTA23726,776
        10         20         30         40         50         60 
MAIYLTELDS KSLDFPPAEN ALADPNGLLA FGGDLTPERL IAAYHHGIFP WYGPGEPILW 

        70         80         90        100        110        120 
WSPSTRAVFD PNTFLPAKSL KKFQRKAQYQ VSINHATPEV IKLCGNTRPA EETWLNEEMQ 

       130        140        150        160        170        180 
AAYISLALQG VCHSVEVWQD QRLIGGFYGL SIGELFCGES MFSLETNASK IALWYFCRHF 

       190        200        210        220        230 
SEHGGKLIDC QVMNSHLHSL GAFTLPREEF LQRLLCLKQQ RVTSGCFSPQ WLKRHNA 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Vibrio vulnificus CMCP6."
Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.
Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CMCP6.
[2]Rhee J.H., Kim S.Y., Chung S.S., Lee S.E., Choy H.E.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: SEQUENCE REVISION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016795 Genomic DNA. Translation: ABE68813.1.
RefSeqYP_004300165.1. NC_004459.3.

3D structure databases

ProteinModelPortalQ1RS89.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING216895.VV1_3222.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE68813; ABE68813; VV1_3222.
GeneID4484204.
KEGGvvu:VV1_3222.
PATRIC20161019. VBIVibVul94426_1989.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2360.
HOGENOMHOG000102325.
KOK00684.
OMAYRQGIFP.
ProtClustDBPRK00301.

Enzyme and pathway databases

BioCycVVUL216895:GIYM-1889-MONOMER.

Family and domain databases

HAMAPMF_00688. Leu_Phe_trans.
InterProIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMSSF55729. SSF55729. 1 hit.
TIGRFAMsTIGR00667. aat. 1 hit.
ProtoNetSearch...

Entry information

Entry nameLFTR_VIBVU
AccessionPrimary (citable) accession number: Q1RS89
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: May 16, 2006
Last modified: February 19, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families