ID   DULRD_BOVIN             Reviewed;         244 AA.
AC   Q1RMV9;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 19.
DE   RecName: Full=Serine/threonine-protein phosphatase dullard;
DE            EC=3.1.3.16;
GN   Name=DULLARD;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Uterus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Serine/threonine phosphatase which may be required for
CC       proper nuclear membrane morphology. Involved in LPIN1
CC       dephosphorylation. May antagonize BMP signaling (By similarity).
CC   -!- CATALYTIC ACTIVITY: A phosphoprotein + H(2)O = a protein +
CC       phosphate.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass
CC       membrane protein (By similarity). Nucleus membrane; Single-pass
CC       membrane protein (By similarity).
CC   -!- SIMILARITY: Belongs to the dullard family.
CC   -!- SIMILARITY: Contains 1 FCP1 homology domain.
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DR   EMBL; BC114677; AAI14678.1; -; mRNA.
DR   IPI; IPI00688950; -.
DR   RefSeq; NP_001039491.1; -.
DR   UniGene; Bt.27121; -.
DR   Ensembl; ENSBTAG00000019443; Bos taurus.
DR   GeneID; 509192; -.
DR   KEGG; bta:509192; -.
DR   HOVERGEN; Q1RMV9; -.
DR   OMA; Q1RMV9; DKLDNNR.
DR   BRENDA; 3.1.3.16; 251.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.
DR   InterPro; IPR011948; Dullard.
DR   InterPro; IPR004274; NIF.
DR   Pfam; PF03031; NIF; 1.
DR   SMART; SM00577; CPDc; 1.
DR   TIGRFAMs; TIGR02251; HIF-SF_euk; 1.
DR   PROSITE; PS50969; FCP1; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Hydrolase; Membrane; Nucleus;
KW   Protein phosphatase; Transmembrane.
FT   CHAIN         1    244       Serine/threonine-protein phosphatase
FT                                dullard.
FT                                /FTId=PRO_0000297966.
FT   TRANSMEM      7     29       Potential.
FT   DOMAIN       57    224       FCP1 homology.
SQ   SEQUENCE   244 AA;  28393 MW;  44494AC37D7E2F30 CRC64;
     MMRTQCLLGL RTFVAFAAKL WSFFIYLLRR QIRTVIQYQT VRYDILPLSP VSRNRLSQVK
     RKILVLDLDE TLIHSHHDGV LRPTVRPGTP PDFILKVVID KHPVRFFVHK RPHVDFFLEV
     VSQWYELVVF TASMEIYGSA VADKLDNSRS ILKRRYYRQH CTLELGSYIK DLSVVHSDLS
     SIVILDNSPG AYRSHPDNAI PIKSWFSDPS DTALLNLLPM LDALRFTADV RSVLSRNLHQ
     HRLW
//