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Protein

Angiopoietin-related protein 1

Gene

ANGPTL1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Angiopoietin-related protein 1
Alternative name(s):
Angiopoietin-like protein 1
Gene namesi
Name:ANGPTL1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000027883724 – 491Angiopoietin-related protein 1Add BLAST468

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi160N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi188N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi280 ↔ 309PROSITE-ProRule annotation
Disulfide bondi432 ↔ 445PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ1RMR1.
PRIDEiQ1RMR1.

Expressioni

Gene expression databases

BgeeiENSBTAG00000010719.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000014193.

Structurei

3D structure databases

ProteinModelPortaliQ1RMR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini271 – 491Fibrinogen C-terminalPROSITE-ProRule annotationAdd BLAST221

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili80 – 168Sequence analysisAdd BLAST89

Keywords - Domaini

Coiled coil, Signal

Phylogenomic databases

eggNOGiKOG2579. Eukaryota.
ENOG410ZYS4. LUCA.
GeneTreeiENSGT00760000118809.
HOGENOMiHOG000037129.
HOVERGENiHBG103336.
InParanoidiQ1RMR1.
OMAiLWCENSL.
OrthoDBiEOG091G03M1.
TreeFamiTF336658.

Family and domain databases

CDDicd00087. FReD. 1 hit.
Gene3Di3.90.215.10. 1 hit.
4.10.530.10. 1 hit.
InterProiView protein in InterPro
IPR036056. Fibrinogen-like_C.
IPR014716. Fibrinogen_a/b/g_C_1.
IPR014715. Fibrinogen_a/b/g_C_2.
IPR002181. Fibrinogen_a/b/g_C_dom.
IPR020837. Fibrinogen_CS.
PfamiView protein in Pfam
PF00147. Fibrinogen_C. 1 hit.
SMARTiView protein in SMART
SM00186. FBG. 1 hit.
SUPFAMiSSF56496. SSF56496. 1 hit.
PROSITEiView protein in PROSITE
PS00514. FIBRINOGEN_C_1. 1 hit.
PS51406. FIBRINOGEN_C_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q1RMR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAFIWTLSV LFFLLMGIGH GRGRQFKIKK ITQRRYPRAT DGKEDAKKCS
60 70 80 90 100
YTFLVPEQKI TGPICVNTKG QDAGTIKDMI TRMDLENLKD VLSKQKREID
110 120 130 140 150
VLQLVVDVDG NIVNEVKLLR KESRNMNSRV TQLYMQLLHE IIRKRDNSLE
160 170 180 190 200
LSQLENKILN VTTEMLKMAT RYRELEVKYA SLTDLVNNQS VMITLLEEQC
210 220 230 240 250
LRIFSRQDPH VSPPLVQVVP QHIPNSHQYT PGLLGGNEIQ RDPGYPRDLM
260 270 280 290 300
PPPDLVTSPT KSPLKIPPVT FINEGPYKDC QHAKDAGHSV SGIYMIKPEN
310 320 330 340 350
SNGPMQLWCE NSLDPGGWTV IQKRTDGSVN FFRNWENYKK GFGNIDGEYW
360 370 380 390 400
LGLENIYLLS NQDNYKLLIE LEDWSDKKVY AEYSSFRLEP ESEFYRLRLG
410 420 430 440 450
TYQGNAGDSM MWHNGKQFTT LDRDKDMYAG NCAHFHKGGW WYNACAHSNL
460 470 480 490
NGVWYRGGHY RSKYQDGIFW AEYRGGSYSL RAVQMLIKPI D
Length:491
Mass (Da):56,674
Last modified:May 16, 2006 - v1
Checksum:i5275247C15D3FB2F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU599224 mRNA. Translation: ACD50900.1.
EU599231 Genomic DNA. Translation: ACD50907.1.
BC114763 mRNA. Translation: AAI14764.1.
RefSeqiNP_001068894.1. NM_001075426.1.
XP_015330623.1. XM_015475137.1.
UniGeneiBt.16731.

Genome annotation databases

EnsembliENSBTAT00000014193; ENSBTAP00000014193; ENSBTAG00000010719.
GeneIDi509971.
KEGGibta:509971.

Similar proteinsi

Entry informationi

Entry nameiANGL1_BOVIN
AccessioniPrimary (citable) accession number: Q1RMR1
Secondary accession number(s): B2Z4A9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: May 16, 2006
Last modified: October 25, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome