ARHGAP12 protein - Homo sapiens (Human)

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Unreviewed, UniProtKB/TrEMBL Q1RLN5 (Q1RLN5_HUMAN)

Last modified November 25, 2008. Version 20. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
ARHGAP12 protein EMBL AAI15364.1

Gene names

Name:

ARHGAP12 EMBL AAI15364.1

Organism

Homo sapiens (Human) EMBL AAI15364.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	799 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 PH domain. RuleBase RU003350V0

Contains 1 Rho-GAP domain. Spearmint SPM000198

Contains 1 SH3 domain. RuleBase RU003338V3

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338V3
Gene Ontology (GO)
Biological process	signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q1RLN5-1 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: A043F115200F2A11
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799

90,874

        10         20         30         40         50         60 
MKMADRSGKI IPGQVYIEVE YDYEYEAKDR KIVIKQGERY ILVKKTNDDW WQVKPDENSK 

        70         80         90        100        110        120 
AFYVPAQYVK EVTRKALMPP VKQVAGLPNN STKIMQSLHL QRSTENVNKL PELSSFGKPS 

       130        140        150        160        170        180 
SSVQGTGLIR DANQNFGPSY NQGQTVNLSL DLTHNNGKFN NDSHSPKVSS QNRTRSFGHF 

       190        200        210        220        230        240 
PGPEFLDVEK TSFSQEQSCD SAGEGSERIH QDSESGDELS SSSTEQIRAT TPPNQGRPDS 

       250        260        270        280        290        300 
PVYANLQELK ISQSALPPLP GSPAIQINGE WETHKDSSGR CYYYNRGTQE RTWKPPRWTR 

       310        320        330        340        350        360 
DASISKGDFQ NPGDQEWLKH VDDQGRQYYY SADGSRSEWE LPKYNASSQQ QREIIKSRSL 

       370        380        390        400        410        420 
DRRLQEPIVL TKWRHSTIVL DTNDKESPTA SKPCFPENES SPSSPKHQDT ASSPKDQEKY 

       430        440        450        460        470        480 
GLLNVTKIAE NGKKVRKNWL SSWAVLQGSS LLFTKTQGSS TSWFGSNQSK PEFTVDLKGA 

       490        500        510        520        530        540 
TIEMASKDKS SKKNVFELKT RQGTELLIQS DNDTVINDWF KVLSSTINNQ AVETDEGIEE 

       550        560        570        580        590        600 
EIPDSPGIEK HDKEKEQKDP KKLRSFKVSS IDSSEQKKTK KNLKKFLTRR PTLQAVREKG 

       610        620        630        640        650        660 
YIKDQVFGSN LANLCQRENG TVPKFVKLCI EHVEEHGLDI DGIYRVSGNL AVIQKLRFAV 

       670        680        690        700        710        720 
NHDEKLDLND SKWEDIHVIT GALKMFFREL PEPLFTFNHF NDFVNAIKQE PRQRVAAVKD 

       730        740        750        760        770        780 
LIRQLPKPNQ DTMQILFRHL RRVIENGEKN RMTYQSIAIV FGPTLLKPEK ETGNIAVHTV 

       790 
YQNQIVELIL LELSSIFGR

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI15364.1.

Cross-references

Sequence databases
	BC115362 mRNA. Translation: AAI15363.1. BC115363 mRNA. Translation: AAI15364.1.
UniGene	Hs.499264
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000165322. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:16348. ARHGAP12.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q1RLN5.
Gene expression databases
ArrayExpress	Q1RLN5.
Family and domain databases
InterPro	IPR011993. PH_type. IPR001849. Pleckstrin_homology. IPR015767. Rho_GTPase_activating. IPR000198. RhoGAP. IPR001452. SH3_domain. IPR001202. WW_Rsp5_WWP. [Graphical view]
Gene3D	G3DSA:2.30.29.30. PH_type. 1 hit. G3DSA:1.10.555.10. RhoGAP. 1 hit.
PANTHER	PTHR23181. Rho_GTPase_activating. 1 hit.
Pfam	PF00169. PH. 1 hit. PF00620. RhoGAP. 1 hit. PF00018. SH3_1. 1 hit. PF00397. WW. 2 hits. [Graphical view]
SMART	SM00233. PH. 1 hit. SM00324. RhoGAP. 1 hit. SM00326. SH3. 1 hit. SM00456. WW. 2 hits. [Graphical view]
PROSITE	PS50003. PH_DOMAIN. 1 hit. PS50238. RHOGAP. 1 hit. PS50002. SH3. 1 hit. PS50020. WW_DOMAIN_2. 2 hits. [Graphical view]

Entry information

Entry name

Q1RLN5_HUMAN

Accession

Primary (citable) accession number: Q1RLN5

Entry history

Integrated into UniProtKB/TrEMBL:	May 16, 2006
Last sequence update:	May 16, 2006
Last modified:	November 25, 2008
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information