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Q1RKN2

- PDRP_RICBR

UniProt

Q1RKN2 - PDRP_RICBR

Protein

Putative pyruvate, phosphate dikinase regulatory protein

Gene

RBE_0001

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (16 May 2006)
      Previous versions | rss
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    Functioni

    Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.UniRule annotation

    Catalytic activityi

    ADP + [pyruvate, phosphate dikinase] = AMP + [pyruvate, phosphate dikinase] phosphate.UniRule annotation
    [Pyruvate, phosphate dikinase] phosphate + phosphate = [pyruvate, phosphate dikinase] + diphosphate.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi149 – 1568ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRBEL336407:GJCY-1-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative pyruvate, phosphate dikinase regulatory proteinUniRule annotation (EC:2.7.11.32UniRule annotation, EC:2.7.4.27UniRule annotation)
    Short name:
    PPDK regulatory proteinUniRule annotation
    Gene namesi
    Ordered Locus Names:RBE_0001
    OrganismiRickettsia bellii (strain RML369-C)
    Taxonomic identifieri336407 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
    ProteomesiUP000001951: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 273273Putative pyruvate, phosphate dikinase regulatory proteinPRO_0000277932Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi336407.RBE_0001.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1806.
    HOGENOMiHOG000218052.
    KOiK09773.
    OMAiSFFHLHL.
    OrthoDBiEOG6KHG2N.

    Family and domain databases

    HAMAPiMF_00921. PDRP.
    InterProiIPR005177. Kinase-pyrophosphorylase.
    IPR026565. PPDK_reg.
    [Graphical view]
    PfamiPF03618. Kinase-PPPase. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1RKN2-1 [UniParc]FASTAAdd to Basket

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    MTKLIIHLVS DSSVQTAKSA AHSALAQFTS LKPKLYHWPM IRNSELLKEV    50
    LSKIESKHGI VLYTIADQEL RKTLTKFCYE LKIPCISVIS KIIKEMSVFS 100
    GIEIEKEQNY NYKFDKTYFD TLNAIDYAIR HDDGQLLNEL QFADIILIGP 150
    SRTSKTPTSV FLAYNGLKTA NIPYVYNCPF PDFIEKDIDQ LVVGLVINPN 200
    RLIEIRETRL NLLQINENRN YTDFNIVQKE CLEVKKICEL RNWPVIDVST 250
    KSIEETAALI MRIYYNKKNK YKK 273
    Length:273
    Mass (Da):31,638
    Last modified:May 16, 2006 - v1
    Checksum:iAC8401E0FF49DB15
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE04082.1.
    RefSeqiWP_011476697.1. NC_007940.1.
    YP_537171.1. NC_007940.1.

    Genome annotation databases

    EnsemblBacteriaiABE04082; ABE04082; RBE_0001.
    GeneIDi3996153.
    KEGGirbe:RBE_0001.
    PATRICi17881231. VBIRicBel102610_0001.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE04082.1 .
    RefSeqi WP_011476697.1. NC_007940.1.
    YP_537171.1. NC_007940.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 336407.RBE_0001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE04082 ; ABE04082 ; RBE_0001 .
    GeneIDi 3996153.
    KEGGi rbe:RBE_0001.
    PATRICi 17881231. VBIRicBel102610_0001.

    Phylogenomic databases

    eggNOGi COG1806.
    HOGENOMi HOG000218052.
    KOi K09773.
    OMAi SFFHLHL.
    OrthoDBi EOG6KHG2N.

    Enzyme and pathway databases

    BioCyci RBEL336407:GJCY-1-MONOMER.

    Family and domain databases

    HAMAPi MF_00921. PDRP.
    InterProi IPR005177. Kinase-pyrophosphorylase.
    IPR026565. PPDK_reg.
    [Graphical view ]
    Pfami PF03618. Kinase-PPPase. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
      Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
      PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RML369-C.

    Entry informationi

    Entry nameiPDRP_RICBR
    AccessioniPrimary (citable) accession number: Q1RKN2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 20, 2007
    Last sequence update: May 16, 2006
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia bellii strain RML369-C
      Rickettsia bellii (strain RML369-C): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3