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Q1RKL2 (SAM_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
S-adenosylmethionine uptake transporter
Gene names
Name:sam
Ordered Locus Names:RBE_0021
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length291 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transports S-adenosylmethionine By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family. [View classification]

Contains 2 EamA domains.

Ontologies

Keywords
   Biological processAmino-acid transport
Transport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainRepeat
Transmembrane
Transmembrane helix
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processamino acid transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 291291S-adenosylmethionine uptake transporter
PRO_0000280994

Regions

Transmembrane4 – 2421Helical; Potential
Transmembrane41 – 6121Helical; Potential
Transmembrane74 – 9118Helical; Potential
Transmembrane98 – 11821Helical; Potential
Transmembrane121 – 14121Helical; Potential
Transmembrane148 – 16821Helical; Potential
Transmembrane178 – 19821Helical; Potential
Transmembrane206 – 22621Helical; Potential
Transmembrane237 – 25721Helical; Potential
Transmembrane260 – 28021Helical; Potential
Domain21 – 141121EamA 1
Domain160 – 280121EamA 2

Sequences

Sequence LengthMass (Da)Tools
Q1RKL2 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 88DDA7CFB46BF997

FASTA29132,591
        10         20         30         40         50         60 
MNDALKTYSI GIGWFLLSLV SSSANDVMSK YLGTRLHSFE VAFFRFFFSS IVLLPFVVYY 

        70         80         90        100        110        120 
GKNTLKTSRP FVHILRGLLL FFGMTSWTYG LSIAPVTTAT VISFSIPLFT LILAVFFLNE 

       130        140        150        160        170        180 
NIIWQRWVVT IVGFVGLVIT LKPHAEDFNP EMLYFVLAAI SFAMLDIINK KFVVKESMIS 

       190        200        210        220        230        240 
MLFYSAIVTA VVSIPAAANY WLTPTLFELA LLFILGSSGS LILFLLLKAF SMVDATATAP 

       250        260        270        280        290 
YRYLELVISA IAAYFIFNEF PDKSTLHGAV IIIPATLFII YSEKKAMSKK I 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE04102.1.
RefSeqYP_537191.1. NC_007940.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING336407.RBE_0021.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE04102; ABE04102; RBE_0021.
GeneID3996098.
KEGGrbe:RBE_0021.
PATRIC17881281. VBIRicBel102610_0025.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0697.
HOGENOMHOG000264283.
KOK15270.
OMAPFFWEVP.
OrthoDBEOG6DG2QT.
ProtClustDBCLSK870734.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-22-MONOMER.

Family and domain databases

InterProIPR000620. DMT.
[Graphical view]
PfamPF00892. EamA. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSAM_RICBR
AccessionPrimary (citable) accession number: Q1RKL2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: May 16, 2006
Last modified: February 19, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names