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Q1RKI0

- GREA_RICBR

UniProt

Q1RKI0 - GREA_RICBR

Protein

Transcription elongation factor GreA

Gene

greA

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (16 May 2006)
      Previous versions | rss
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    Functioni

    Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.UniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of DNA-templated transcription, elongation Source: InterPro
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciRBEL336407:GJCY-55-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcription elongation factor GreAUniRule annotation
    Alternative name(s):
    Transcript cleavage factor GreAUniRule annotation
    Gene namesi
    Name:greAUniRule annotation
    Ordered Locus Names:RBE_0053
    OrganismiRickettsia bellii (strain RML369-C)
    Taxonomic identifieri336407 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
    ProteomesiUP000001951: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 162162Transcription elongation factor GreAPRO_0000277900Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi336407.RBE_0053.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1RKI0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili44 – 6926UniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the GreA/GreB family.UniRule annotation

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiCOG0782.
    HOGENOMiHOG000241145.
    KOiK03624.
    OMAiHAQIIDV.
    OrthoDBiEOG686NQ9.

    Family and domain databases

    Gene3Di1.10.287.180. 1 hit.
    3.10.50.30. 1 hit.
    HAMAPiMF_00105. GreA_GreB.
    InterProiIPR018151. TF_GreA/GreB_CS.
    IPR006359. Tscrpt_elong_fac_GreA.
    IPR028624. Tscrpt_elong_fac_GreA/B.
    IPR001437. Tscrpt_elong_fac_GreA/B_C.
    IPR023459. Tscrpt_elong_fac_GreA/B_fam.
    IPR022691. Tscrpt_elong_fac_GreA/B_N.
    [Graphical view]
    PfamiPF01272. GreA_GreB. 1 hit.
    PF03449. GreA_GreB_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006092. GreA_GreB. 1 hit.
    SUPFAMiSSF46557. SSF46557. 1 hit.
    TIGRFAMsiTIGR01462. greA. 1 hit.
    PROSITEiPS00829. GREAB_1. 1 hit.
    PS00830. GREAB_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1RKI0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMAKFPITDQ GFEKLEHELK HLKHVERKKV SEDIAEARAH GDLSENAEYE    50
    AAREKQAFVE ARIKHLEDIT ARAEIINVAK LSGDSIKFGA TVVLIDDETE 100
    EEVMYHIVGE YEADITKKRV SIASPIAKAL IGKSVGDIVE VMTPGGVKSY 150
    EVVTIKYEEL VF 162
    Length:162
    Mass (Da):18,115
    Last modified:May 16, 2006 - v1
    Checksum:i2D90AA76DC96BC8A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE04134.1.
    RefSeqiYP_537223.1. NC_007940.1.

    Genome annotation databases

    EnsemblBacteriaiABE04134; ABE04134; RBE_0053.
    GeneIDi3995017.
    KEGGirbe:RBE_0053.
    PATRICi17881349. VBIRicBel102610_0059.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE04134.1 .
    RefSeqi YP_537223.1. NC_007940.1.

    3D structure databases

    ProteinModelPortali Q1RKI0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 336407.RBE_0053.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE04134 ; ABE04134 ; RBE_0053 .
    GeneIDi 3995017.
    KEGGi rbe:RBE_0053.
    PATRICi 17881349. VBIRicBel102610_0059.

    Phylogenomic databases

    eggNOGi COG0782.
    HOGENOMi HOG000241145.
    KOi K03624.
    OMAi HAQIIDV.
    OrthoDBi EOG686NQ9.

    Enzyme and pathway databases

    BioCyci RBEL336407:GJCY-55-MONOMER.

    Family and domain databases

    Gene3Di 1.10.287.180. 1 hit.
    3.10.50.30. 1 hit.
    HAMAPi MF_00105. GreA_GreB.
    InterProi IPR018151. TF_GreA/GreB_CS.
    IPR006359. Tscrpt_elong_fac_GreA.
    IPR028624. Tscrpt_elong_fac_GreA/B.
    IPR001437. Tscrpt_elong_fac_GreA/B_C.
    IPR023459. Tscrpt_elong_fac_GreA/B_fam.
    IPR022691. Tscrpt_elong_fac_GreA/B_N.
    [Graphical view ]
    Pfami PF01272. GreA_GreB. 1 hit.
    PF03449. GreA_GreB_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006092. GreA_GreB. 1 hit.
    SUPFAMi SSF46557. SSF46557. 1 hit.
    TIGRFAMsi TIGR01462. greA. 1 hit.
    PROSITEi PS00829. GREAB_1. 1 hit.
    PS00830. GREAB_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
      Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
      PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RML369-C.

    Entry informationi

    Entry nameiGREA_RICBR
    AccessioniPrimary (citable) accession number: Q1RKI0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 20, 2007
    Last sequence update: May 16, 2006
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia bellii strain RML369-C
      Rickettsia bellii (strain RML369-C): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3