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Q1RKI0

- GREA_RICBR

UniProt

Q1RKI0 - GREA_RICBR

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Protein
Transcription elongation factor GreA
Gene
greA, RBE_0053
Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides By similarity.UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. regulation of DNA-templated transcription, elongation Source: InterPro
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-55-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription elongation factor GreA
Alternative name(s):
Transcript cleavage factor GreA
Gene namesi
Name:greA
Ordered Locus Names:RBE_0053
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 162162Transcription elongation factor GreAUniRule annotation
PRO_0000277900Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi336407.RBE_0053.

Structurei

3D structure databases

ProteinModelPortaliQ1RKI0.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili44 – 6926 Reviewed prediction
Add
BLAST

Sequence similaritiesi

Belongs to the GreA/GreB family.

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiCOG0782.
HOGENOMiHOG000241145.
KOiK03624.
OMAiHAQIIDV.
OrthoDBiEOG686NQ9.

Family and domain databases

Gene3Di1.10.287.180. 1 hit.
3.10.50.30. 1 hit.
HAMAPiMF_00105. GreA_GreB.
InterProiIPR018151. TF_GreA/GreB_CS.
IPR006359. Tscrpt_elong_fac_GreA.
IPR028624. Tscrpt_elong_fac_GreA/B.
IPR001437. Tscrpt_elong_fac_GreA/B_C.
IPR023459. Tscrpt_elong_fac_GreA/B_fam.
IPR022691. Tscrpt_elong_fac_GreA/B_N.
[Graphical view]
PfamiPF01272. GreA_GreB. 1 hit.
PF03449. GreA_GreB_N. 1 hit.
[Graphical view]
PIRSFiPIRSF006092. GreA_GreB. 1 hit.
SUPFAMiSSF46557. SSF46557. 1 hit.
TIGRFAMsiTIGR01462. greA. 1 hit.
PROSITEiPS00829. GREAB_1. 1 hit.
PS00830. GREAB_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1RKI0-1 [UniParc]FASTAAdd to Basket

« Hide

MMAKFPITDQ GFEKLEHELK HLKHVERKKV SEDIAEARAH GDLSENAEYE    50
AAREKQAFVE ARIKHLEDIT ARAEIINVAK LSGDSIKFGA TVVLIDDETE 100
EEVMYHIVGE YEADITKKRV SIASPIAKAL IGKSVGDIVE VMTPGGVKSY 150
EVVTIKYEEL VF 162
Length:162
Mass (Da):18,115
Last modified:May 16, 2006 - v1
Checksum:i2D90AA76DC96BC8A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000087 Genomic DNA. Translation: ABE04134.1.
RefSeqiYP_537223.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE04134; ABE04134; RBE_0053.
GeneIDi3995017.
KEGGirbe:RBE_0053.
PATRICi17881349. VBIRicBel102610_0059.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000087 Genomic DNA. Translation: ABE04134.1 .
RefSeqi YP_537223.1. NC_007940.1.

3D structure databases

ProteinModelPortali Q1RKI0.
ModBasei Search...

Protein-protein interaction databases

STRINGi 336407.RBE_0053.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE04134 ; ABE04134 ; RBE_0053 .
GeneIDi 3995017.
KEGGi rbe:RBE_0053.
PATRICi 17881349. VBIRicBel102610_0059.

Phylogenomic databases

eggNOGi COG0782.
HOGENOMi HOG000241145.
KOi K03624.
OMAi HAQIIDV.
OrthoDBi EOG686NQ9.

Enzyme and pathway databases

BioCyci RBEL336407:GJCY-55-MONOMER.

Family and domain databases

Gene3Di 1.10.287.180. 1 hit.
3.10.50.30. 1 hit.
HAMAPi MF_00105. GreA_GreB.
InterProi IPR018151. TF_GreA/GreB_CS.
IPR006359. Tscrpt_elong_fac_GreA.
IPR028624. Tscrpt_elong_fac_GreA/B.
IPR001437. Tscrpt_elong_fac_GreA/B_C.
IPR023459. Tscrpt_elong_fac_GreA/B_fam.
IPR022691. Tscrpt_elong_fac_GreA/B_N.
[Graphical view ]
Pfami PF01272. GreA_GreB. 1 hit.
PF03449. GreA_GreB_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF006092. GreA_GreB. 1 hit.
SUPFAMi SSF46557. SSF46557. 1 hit.
TIGRFAMsi TIGR01462. greA. 1 hit.
PROSITEi PS00829. GREAB_1. 1 hit.
PS00830. GREAB_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiGREA_RICBR
AccessioniPrimary (citable) accession number: Q1RKI0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: May 16, 2006
Last modified: May 14, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi