Q1RKH3 (TRUA_RICBR) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 43.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: tRNA pseudouridine synthase A EC=5.4.99.12 Alternative name(s): tRNA pseudouridine(38-40) synthase tRNA pseudouridylate synthase I tRNA-uridine isomerase I | ||||
| Gene names |
| ||||
| Organism | Rickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 336407 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia |
Protein attributes
| Sequence length | 245 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs By similarity. HAMAP MF_00171 |
| Catalytic activity | tRNA uridine(38-40) = tRNA pseudouridine(38-40). HAMAP MF_00171 |
| Subunit structure | Homodimer By similarity. HAMAP MF_00171 |
| Sequence similarities | Belongs to the tRNA pseudouridine synthase TruA family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | tRNA processing |
| Molecular function | Isomerase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | pseudouridine synthesis Inferred from electronic annotation. Source: InterPro tRNA processingInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | RNA binding Inferred from electronic annotation. Source: InterPro pseudouridine synthase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 245 | 245 | tRNA pseudouridine synthase A HAMAP MF_00171 | PRO_0000278055 | |||||
Sites | |||||||||
| Active site | 52 | 1 | Nucleophile By similarity | ||||||
| Binding site | 111 | 1 | Substrate By similarity | ||||||
Sequences
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References
| [1] | "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens." Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D. PLoS Genet. 2:733-744(2006) [PubMed: 16703114] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RML369-C. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000087 Genomic DNA. Translation: ABE04141.1. |
| RefSeq | YP_537230.1. NC_007940.1. |
3D structure databases | |
| ProteinModelPortal | Q1RKH3. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q1RKH3. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 3995024. |
| GenomeReviews | Gene locus RBE_0060 in contig CP000087_GR. |
| KEGG | rbe:RBE_0060. |
| PATRIC | 17881363. VBIRicBel102610_0066. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0101. |
| HOGENOM | HBG621020. |
| OMA | RHYRYRI. |
| ProtClustDB | PRK00021. |
Enzyme and pathway databases | |
| BioCyc | RBEL336407:RBE_0060-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00171. TruA. [Tree] |
| InterPro | IPR020103. PsdUridine_synth_cat_dom. IPR001406. PsdUridine_synth_TruA. IPR020097. PsdUridine_synth_TruA_a/b_dom. IPR020095. PsdUridine_synth_TruA_C. IPR020094. PsdUridine_synth_TruA_N. [Graphical view] |
| Gene3D | G3DSA:3.30.70.580. PseudoU_synth_1. 1 hit. G3DSA:3.30.70.660. PseudoU_synth_1. 1 hit. |
| KO | K06173. |
| PANTHER | PTHR11142. PseudoU_synth_1. 1 hit. |
| Pfam | PF01416. PseudoU_synth_1. 2 hits. [Graphical view] |
| PIRSF | PIRSF001430. tRNA_psdUrid_synth. 1 hit. |
| SUPFAM | SSF55120. PsdUridine_synth_cat_dom. 1 hit. |
| TIGRFAMs | TIGR00071. HisT_truA. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | TRUA_RICBR | ||||||||
| Accession | Primary (citable) accession number: Q1RKH3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Rickettsia bellii strain RML369-C Rickettsia bellii (strain RML369-C): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

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