Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q1RKH3 (TRUA_RICBR)

Last modified December 15, 2009. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    tRNA pseudouridine synthase A
    EC=5.4.99.12
Alternative name(s):
    tRNA-uridine isomerase I
    tRNA pseudouridylate synthase I
Gene names
Name: truA
Ordered Locus Names: RBE_0060
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsia

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs By similarity.

Catalytic activity

tRNA uridine = tRNA pseudouridine. HAMAP MF_00171

Sequence similarities

Belongs to the tRNA pseudouridine synthase truA family.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtRNA pseudouridine synthesis

Inferred from electronic annotation. Source: HAMAP

   Molecular functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 245245tRNA pseudouridine synthase A HAMAP MF_00171
PRO_0000278055

Sites

Active site521Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1RKH3-1 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: BDECC4BB92801A49

FASTA24527,982
        10         20         30         40         50         60 
MYRYKISVEY LGTNLAGWQR QSGVMSVQQI LEEAIYKFSG EQVTLFGSGR TDAGVHAIGQ 

        70         80         90        100        110        120 
IAHFDLSKYF EPYKIIRAIN YFTRPYIVGV CNCELVDNNF HARFSAIARH YVYRILNRPY 

       130        140        150        160        170        180 
PSVIDFDRVW WISVPLDVSA MQKSSLYLLG KHNFTSFRAS SCQSKSPIKT LTKLDIIKEN 

       190        200        210        220        230        240 
EEIKLYFSAP SFLHHMVRNI VGSLVLVGKN IWQAEQMQQV LEVADRKAAG PTAPACGLYF 


IKADY 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed: 16703114] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000087 Genomic DNA. Translation: ABE04141.1.
RefSeqYP_537230.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ1RKH3.

Genome annotation databases

GeneID3995024.
GenomeReviewsGene locus RBE_0060 in contig CP000087_GR.
KEGGrbe:RBE_0060.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG621020.
OMAQSKTPFR.

Enzyme and pathway databases

BioCycRBEL336407:RBE_0060-MON.

Family and domain databases

HAMAPMF_00171.
[Tree]
InterProIPR020103. PsdUridine_synth_cat_dom.
IPR001406. PsdUridine_synth_TruA.
IPR020097. PsdUridine_synth_TruA_a/b_dom.
IPR020095. PsdUridine_synth_TruA_C.
IPR020094. PsdUridine_synth_TruA_N.
[Graphical view]
Gene3DG3DSA:3.30.70.580. PseudoU_synth_1. 1 hit.
G3DSA:3.30.70.660. PseudoU_synth_1. 1 hit.
PANTHERPTHR11142. PseudoU_synth_1. 1 hit.
PfamPF01416. PseudoU_synth_1. 2 hits.
[Graphical view]
PIRSFPIRSF001430. tRNA_psdUrid_synth. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRUA_RICBR
AccessionPrimary (citable) accession number: Q1RKH3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: May 16, 2006
Last modified: December 15, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents