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Q1RKF8

- UDG_RICBR

UniProt

Q1RKF8 - UDG_RICBR

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Protein

UDP-glucose 6-dehydrogenase

Gene

udg

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei260 – 2601By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi2 – 1918NADSequence AnalysisAdd
BLAST

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. UDP-glucose 6-dehydrogenase activity Source: UniProtKB-EC

GO - Biological processi

  1. polysaccharide biosynthetic process Source: InterPro
  2. UDP-glucuronate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-77-MONOMER.
UniPathwayiUPA00038; UER00491.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucose 6-dehydrogenase (EC:1.1.1.22)
Short name:
UDP-Glc dehydrogenase
Short name:
UDP-GlcDH
Short name:
UDPGDH
Gene namesi
Name:udg
Ordered Locus Names:RBE_0075
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 434434UDP-glucose 6-dehydrogenasePRO_0000281044Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi336407.RBE_0075.

Structurei

3D structure databases

ProteinModelPortaliQ1RKF8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1004.
HOGENOMiHOG000153773.
KOiK00012.
OMAiRETNPTA.
OrthoDBiEOG6ZSP7N.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR017476. UDP-Glc/GDP-Man.
IPR014027. UDP-Glc/GDP-Man_DH_C.
IPR014026. UDP-Glc/GDP-Man_DH_dimer.
IPR001732. UDP-Glc/GDP-Man_DH_N.
IPR028357. UDPglc_DH_bac.
[Graphical view]
PANTHERiPTHR11374. PTHR11374. 1 hit.
PfamiPF00984. UDPG_MGDP_dh. 1 hit.
PF03720. UDPG_MGDP_dh_C. 1 hit.
PF03721. UDPG_MGDP_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF500134. UDPglc_DH_bac. 1 hit.
PIRSF000124. UDPglc_GDPman_dh. 1 hit.
SMARTiSM00984. UDPG_MGDP_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF52413. SSF52413. 1 hit.
TIGRFAMsiTIGR03026. NDP-sugDHase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1RKF8-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MNITFIGSGY VGLVSGVMMS YLGHNVTCLD NDEAKISKLN KRILPIYETK
60 70 80 90 100
LDKYFTQALE HERLKFTSFY NEELKNTEAV FITVGTPSKA SGEADLSYVY
110 120 130 140 150
EAIDKISLHI NKDCLIVIKS TVPPNSCNNI INYLKEKGFS FNVASNPEFL
160 170 180 190 200
REGNAVEDFL YPDRIVIGVN NKESEDILRK IYMPLTDNGA ELVITDLVTA
210 220 230 240 250
ELIKYGSNSF LATKIAFINE MANLCEKIGA DIKNLSKGIG LDKRIGTAFL
260 270 280 290 300
NAGPGFGGSC FPKDILALNS IIKNNYIDSK ILEAVIRSNK ERPSLMVDKI
310 320 330 340 350
ATLLDEDLKG KNIAVLGLTY KAGTDDVRAS PAIEIIKNLL DKGTYVKAFD
360 370 380 390 400
PMGLENSQKT FQNENLLYLD SAIKVCDSSD AIIITTEWSE FQALDWQKIY
410 420 430
SLVKTPIIID LRNILKADEV ESIGFRYYTV GSKI
Length:434
Mass (Da):48,268
Last modified:May 16, 2006 - v1
Checksum:i53410C577FA28771
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000087 Genomic DNA. Translation: ABE04156.1.
RefSeqiYP_537245.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE04156; ABE04156; RBE_0075.
GeneIDi3994979.
KEGGirbe:RBE_0075.
PATRICi17881395. VBIRicBel102610_0082.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000087 Genomic DNA. Translation: ABE04156.1 .
RefSeqi YP_537245.1. NC_007940.1.

3D structure databases

ProteinModelPortali Q1RKF8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 336407.RBE_0075.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE04156 ; ABE04156 ; RBE_0075 .
GeneIDi 3994979.
KEGGi rbe:RBE_0075.
PATRICi 17881395. VBIRicBel102610_0082.

Phylogenomic databases

eggNOGi COG1004.
HOGENOMi HOG000153773.
KOi K00012.
OMAi RETNPTA.
OrthoDBi EOG6ZSP7N.

Enzyme and pathway databases

UniPathwayi UPA00038 ; UER00491 .
BioCyci RBEL336407:GJCY-77-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 2 hits.
InterProi IPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR017476. UDP-Glc/GDP-Man.
IPR014027. UDP-Glc/GDP-Man_DH_C.
IPR014026. UDP-Glc/GDP-Man_DH_dimer.
IPR001732. UDP-Glc/GDP-Man_DH_N.
IPR028357. UDPglc_DH_bac.
[Graphical view ]
PANTHERi PTHR11374. PTHR11374. 1 hit.
Pfami PF00984. UDPG_MGDP_dh. 1 hit.
PF03720. UDPG_MGDP_dh_C. 1 hit.
PF03721. UDPG_MGDP_dh_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF500134. UDPglc_DH_bac. 1 hit.
PIRSF000124. UDPglc_GDPman_dh. 1 hit.
SMARTi SM00984. UDPG_MGDP_dh_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48179. SSF48179. 1 hit.
SSF52413. SSF52413. 1 hit.
TIGRFAMsi TIGR03026. NDP-sugDHase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiUDG_RICBR
AccessioniPrimary (citable) accession number: Q1RKF8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: May 16, 2006
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3