Q1RKB6 (RECA_RICBR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein RecA

Alternative name(s):
Recombinase A

Gene names

Name:	recA
Ordered Locus Names:	RBE_0117

Organism

Rickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]

Taxonomic identifier

336407 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage By similarity. HAMAP MF_00268
Subcellular location	Cytoplasm By similarity HAMAP MF_00268.
Sequence similarities	Belongs to the RecA family.

Ontologies

Keywords
Biological process	DNA damage DNA recombination DNA repair SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA repair Inferred from electronic annotation. Source: UniProtKB-KW SOS response Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA-dependent ATPase activity Inferred from electronic annotation. Source: InterPro single-stranded DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Protein RecA HAMAP MF_00268		PRO_0000278024
Regions
	Nucleotide binding	66 – 73	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1RKB6 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 64F6725A9944B921	FASTA	343	37,151
	10 20 30 40 50 60 MSNIDKEKAV AAALAQIEKS YGKGSVMKLG QRPNVDIESV STGSLGLDIA LGIGGIPKGR 70 80 90 100 110 120 IIEIFGPESS GKTTLTLHLI AEAQKKGGTC AFIDAEHALD PAYAKKLGVN IDELIISQPD 130 140 150 160 170 180 TGEQALEIAD TLIRSGGIDM IIIDSVAALV PKSEIEGEMG DAQMASQARL MSQALRKLTA 190 200 210 220 230 240 SINRTNCITV FINQIRMKIG VMFGSPETTT GGNALKFYAS VRIDIRRIGS IKDKEEVIGS 250 260 270 280 290 300 QTKVKVVKNK VSPPFKTADF DIMYGSGISK EGEIIDLGVK LDIIEKSGSW FSYNSVRIGQ 310 320 330 340 GRENVKQYLK DNPKISNEIE KLVREKSSKV TNINFEQEEE VND

References

[1]

"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens." Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D. PLoS Genet. 2:733-744(2006) [PubMed: 16703114] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RML369-C.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000087 Genomic DNA. Translation: ABE04198.1.
RefSeq	YP_537287.1. NC_007940.1.
3D structure databases
ProteinModelPortal	Q1RKB6.
SMR	Q1RKB6. Positions 6-325.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1RKB6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3994992.
GenomeReviews	Gene locus RBE_0117 in contig CP000087_GR.
KEGG	rbe:RBE_0117.
PATRIC	17881500. VBIRicBel102610_0134.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0468.
HOGENOM	HBG339889.
OMA	TRKGAWY.
ProtClustDB	PRK09354.
Enzyme and pathway databases
BioCyc	RBEL336407:RBE_0117-MONOMER.
Family and domain databases
HAMAP	MF_00268. RecA. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR013765. DNA_recomb/repair_RecA. IPR020584. DNA_recomb/repair_RecA_CS. IPR020588. DNA_recomb_RecA/RadB_ATP-bd. IPR023400. RecA_C. IPR020587. RecA_monomer-monomer_interface. [Graphical view]
Gene3D	G3DSA:3.30.250.10. G3DSA:3.30.250.10. 1 hit.
KO	K03553.
PANTHER	PTHR22942:SF1. RecA. 1 hit.
Pfam	PF00154. RecA. 1 hit. [Graphical view]
PRINTS	PR00142. RECA.
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF54752. SSF54752. 1 hit.
TIGRFAMs	TIGR02012. Tigrfam_recA. 1 hit.
PROSITE	PS00321. RECA_1. 1 hit. PS50162. RECA_2. 1 hit. PS50163. RECA_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECA_RICBR

Accession

Primary (citable) accession number: Q1RKB6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 20, 2007
Last sequence update:	May 16, 2006
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program